Abstract: A combination telephone disinfecting towelette and dispenser for dispensing individual telephone disinfecting towelettes. The combination includes a plurality of telephone disinfecting towelettes each being treated with a disinfectant and in a layered interlocking position with an adjacent one of the plurality of telephone disinfecting towelettes. The plurality of telephone disinfecting towelettes are positioned within the dispenser. The dispenser includes a cylindrical shell including a sealed bottom side and a top side including a recess therein and a device for releasably sealing the recess. The dispenser further includes a device for dividing the dispenser into first and second sections, hermetically sealing the plurality of telephone disinfecting towelettes within the second section whereby a top one of the plurality of telephone disinfecting towelettes extends through the dividing device and into the first section where it may be removed from the dispenser through the recess.