Patents by Inventor Joe Orlando

Joe Orlando has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11326154
    Abstract: The present invention relates to fusion proteins comprising an N-intein polypeptide and an N-intein solubilization partner, and affinity chromatography matrices comprising such fusion proteins, as well as methods of using same.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: May 10, 2022
    Assignee: Merck Patent GmbH
    Inventors: Martin Zillmann, Joe Orlando
  • Publication number: 20190241609
    Abstract: The present invention relates to fusion proteins comprising an N-intein polypeptide and an N-intein solubilization partner, and affinity chromatography matrices comprising such fusion proteins, as well as methods of using same.
    Type: Application
    Filed: April 18, 2019
    Publication date: August 8, 2019
    Inventors: Martin Zillmann, Joe Orlando
  • Patent number: 10308679
    Abstract: The present invention relates to fusion proteins comprising an N-intein polypeptide and an N-intein solubilization partner, and affinity chromatography matrices comprising such fusion proteins, as well as methods of using same.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: June 4, 2019
    Assignee: Merck Patent GmbH
    Inventors: Martin Zillmann, Joe Orlando
  • Publication number: 20170291919
    Abstract: The present invention relates to fusion proteins comprising an N-intein polypeptide and an N-intein solubilization partner, and affinity chromatography matrices comprising such fusion proteins, as well as methods of using same.
    Type: Application
    Filed: October 23, 2015
    Publication date: October 12, 2017
    Inventors: Martin Zillmann, Joe Orlando
  • Patent number: 9376474
    Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: June 28, 2016
    Assignee: EMD Millipore Corporation
    Inventors: Shari Spector, Robert Smith, Joe Orlando, Nanying Bian
  • Publication number: 20160168194
    Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
    Type: Application
    Filed: December 16, 2015
    Publication date: June 16, 2016
    Inventors: Shari Spector, Robert Smith, Joe Orlando, Nanying Bian
  • Patent number: 9234010
    Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: January 12, 2016
    Assignee: EMD Millipore Corporation
    Inventors: Shari Spector, Robert Smith, Joe Orlando, Nanying Bian
  • Publication number: 20150252085
    Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
    Type: Application
    Filed: April 10, 2015
    Publication date: September 10, 2015
    Inventors: Shari Spector, Robert Smith, Joe Orlando, Nanying Bian
  • Patent number: 9018305
    Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: April 28, 2015
    Assignee: EMD Millipore Corporation
    Inventors: Shari Spector, Robert Smith, Joe Orlando, Nanying Bian
  • Publication number: 20150080558
    Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
    Type: Application
    Filed: November 6, 2014
    Publication date: March 19, 2015
    Inventors: Shari Spector, Robert Smith, Joe Orlando, Nanying Bian
  • Patent number: 8895706
    Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylooccus aureus Protein A (SpA), as well as methods of using the same.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: November 25, 2014
    Assignee: EMD Millipore Corporation
    Inventors: Shari Spector, Robert Smith, Joe Orlando, Nanying Bian
  • Publication number: 20140296434
    Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
    Type: Application
    Filed: June 6, 2014
    Publication date: October 2, 2014
    Inventors: Shari Spector, Robert Smith, Joe Orlando, Nanying Bian
  • Patent number: 8754196
    Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
    Type: Grant
    Filed: June 6, 2012
    Date of Patent: June 17, 2014
    Assignee: EMD Millipore Corporation
    Inventors: Shari Spector, Robert Smith, Joe Orlando, Nanying Bian
  • Publication number: 20130046056
    Abstract: The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, Staphylococcus aureus Protein A (SpA), as well as methods of using the same.
    Type: Application
    Filed: June 6, 2012
    Publication date: February 21, 2013
    Applicant: EMD Millipore Corporation
    Inventors: Shari Spector, Robert Smith, Joe Orlando, Nanying Bian