Patents by Inventor Joe R. Wardell

Joe R. Wardell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines
    Patent number: 4340600
    Abstract: 4-Phenyl-1,2,3,4-tetrahydroisoquinolines whose structures have two hydroxy groups substituted at the 3,4-position on the 4-phenyl ring have been found to have renal vasodilating activity upon internal administration. The active ingredients are prepared by cyclizing N-(2-substituted benzyl)-1-(3,4-dimethoxyphenyl)-aminoethanol using either a Lewis acid or an acid cyclizing agent followed by demethylation at the 3,4-dimethoxyphenyl moiety.
    Type: Grant
    Filed: May 22, 1980
    Date of Patent: July 20, 1982
    Assignee: SmithKline Corporation
    Inventors: L. Martin Brenner, Joe R. Wardell, Jr.
  • .alpha.-AMINOALKYL-3-(1,2-DIHYDROXYETHYL)-4-HYDROXY-BENZYL ALCOHOLS HAVING .beta.-ADRENERGIC STIMULANT ACTIVITY
    Patent number: 4012528
    Abstract: .alpha.-Aminoalkyl-3-(1,2-dihydroxyethyl)-4-hydroxy-benzyl alcohols having .beta.-adrenergic stimulant activity, particularly as selective bronchodilators, are disclosed.
    Type: Grant
    Filed: June 13, 1975
    Date of Patent: March 15, 1977
    Assignee: SmithKline Corporation
    Inventors: Timothy Yu-Wen Jen, Carl Kaiser, Joe R. Wardell
  • 3-Substituted-4-hydroxyphenyl-2-piperidylcarbinols as .beta.-adrenergic stimulants
    Patent number: 3985887
    Abstract: 3-Substituted-3-hydroxyphenyl-2-piperidylcarbinols are prepared. These compounds are .beta.-adrenergic stimulants and are useful in particular as bronchodilators.
    Type: Grant
    Filed: June 11, 1975
    Date of Patent: October 12, 1976
    Assignee: SmithKline Corporation
    Inventors: Carl Kaiser, Joe R. Wardell, Jr.