Abstract: The present invention concerns a new gene therapy approach to increase light-sensitivity in degenerating cones in advanced stages of rod-cone dystrophy (RCD) mediated by G-protein-gated-K+ channel (GIRK), in particular GIRK2, activated by G proteins recruited by cone opsin expressed in degenerating cones for use in the treatment of patients with RCD.

Abstract: The present invention concerns a new gene therapy approach to increase light-sensitivity in degenerating cones in advanced stages of rod-cone dystrophy (RCD) mediated by G-protein-gated-K+ channel (GIRK), in particular GIRK2, activated by G proteins recruited by cone opsin expressed in degenerating cones.

Abstract: A start-up plating process for a flow cell battery is disclosed. Upon start-up of the flow-cell stack, catalysts may have deplated from the electrodes. The catalyst is replated to the electrode by application of currents to the stack prior to circulating electrolyte fluids.

Abstract: A start-up plating process for a flow cell battery is disclosed. Upon start-up of the flow-cell stack, catalysts may have deplated from the electrodes. The catalyst is replated to the electrode by application of currents to the stack prior to circulating electrolyte fluids.

Abstract: A start-up plating process for a flow cell battery is disclosed. Upon start-up of the flow-cell stack, catalysts may have deplated from the electrodes. The catalyst is replated to the electrode by application of currents to the stack prior to circulating electrolyte fluids.

Abstract: Under the present invention an audit log for the server environment is obtained and parsed to remove any extraneous information. The parsing operation will typically leave only the previous operations processed by the server environment in the audit log. Thereafter, the parsed audit log is fed back to the server environment. Specifically, each operation in the audit log is fed back to the server environment as a request. Each request will typically have its own thread to simulate concurrent thread activity in the server environment. After the requests have been fed, statistics corresponding to the resulting performance of the server environment will be generated.

Abstract: A polishing apparatus includes a rotatable head assembly including a substrate retainer that incorporates a cavity in the face surface of the substrate retainer for temporarily holding polishing slurry during operation of the polishing apparatus. The cavity resides in the face surface of the substrate retainer at a location adjacent the perimeter surface of the retainer. During operation of the polishing apparatus, slurry flowing along the surface of the polishing pad flows into the cavity where a portion of the slurry is temporarily held. As the head assembly of the polishing apparatus rotates against the polishing pad, slurry continuously flows from the cavity across the polishing pad and is uniformly distributed across the exposed surface of the substrate being polished. An offset in the cavity wall permits used slurry to flow away from the substrate retainer during rotation of the head assembly.