Abstract: The present disclosure relates to orally ingested foamed dosage delivery forms. The present invention employs foamed microtablets to optimize the delivery of nutritional supplements, dietary supplements, functional foods, vitamins, minerals, amino acids, probiotics, herbal extracts and/or pharmaceuticals.

Abstract: The present disclosure provides technologies that allow reduced field of view or fast imaging with reduced image distortion. The first technique capitalizes on the benefit of reduced field of view imaging for full field of view coverage. The second technique allows achieves high resolution 3D images in a focused region. These techniques are expected to have applications for cancer imaging, neuro imaging, and other biomedical imaging areas.

Abstract: A system and method for producing a series of time-resolved magnetic resonance (MR) images is set forth. The system can perform method steps of encoding spatial information into an MRI signal by manipulating a phase of the MRI signal within an MRI system, generating and outputting a phase-encoded MRI signal over time by digitizing a plurality of time points in the MRI signal, repeating the generating and outputting step for a plurality of phase-encoded signals, each phase-encoded signal in synchrony with a trigger, producing a plurality of digitized time points, and reconstructing a series of time resolved MR images, each image of the series of MR images at one specific time point selected from the plurality of digitized time points for each phase-encoded step. Each image in the series of time-resolved MR images corresponding to a specific time point in a cyclic event.

Abstract: Magnetic resonance imaging systems and methods are provided for time-efficiently producing a plurality of image contrasts, the plurality of image contrasts including a first contrast being coupled with a second contrast and acquired over a plurality of key parameters that govern the second contrast to which the first contrast is coupled. In addition, the plurality of image contrasts is used to simultaneously map the first contrast, the second contrast, and additional contrasts.

Abstract: The disclosed apparatus, systems and methods relate to the delivery of personalized nutraceutical products to a subject, comprising a library of actives; a software module; and a dispensing unit. In certain aspects, the system further comprises a packaging unit and a delivery unit. According to certain aspects, the library of actives comprises a plurality of active nutraceutical ingredients formulated for precise dispensing. In further aspects, the software module is constructed and arranged to receive prescription information for the subject and to output dispensing instructions to the dispensing unit. In still further aspects, the dispensing unit is constructed and arranged to receive dispensing instructions from the software module and to dispense one or more actives from the library of actives to form a nutraceutical product, and wherein the dispensing instructions are derived from the prescription information and customized to the nutritional needs of the subject.

Abstract: The disclosed apparatus, systems and methods relate to the delivery of personalized nutraceutical products to a subject, comprising a library of actives; a software module; and a dispensing unit. In certain aspects, the system further comprises a packaging unit and a delivery unit. According to certain aspects, the library of actives comprises a plurality of active nutraceutical ingredients formulated for precise dispensing. In further aspects, the software module is constructed and arranged to receive prescription information for the subject and to output dispensing instructions to the dispensing unit. In still further aspects, the dispensing unit is constructed and arranged to receive dispensing instructions from the software module and to dispense one or more actives from the library of actives to form a nutraceutical product, and wherein the dispensing instructions are derived from the prescription information and customized to the nutritional needs of the subject.

Abstract: A method for deleting or inactivating at least one Satb2 allele or inhibiting expression of a Satb2 gene in one or more starting cells of a subject, to thereby convert the starting cells into small intestine-like cells, and methods of using those cells, is provided.

Abstract: A system and method for producing a series of time-resolved magnetic resonance (MR) images is set forth. The system can perform method steps of encoding spatial information into an MRI signal by manipulating a phase of the MRI signal within an MRI system, generating and outputting a phase-encoded MRI signal over time by digitizing a plurality of time points in the MRI signal, repeating the generating and outputting step for a plurality of phase-encoded signals, each phase-encoded signal in synchrony with a trigger, producing a plurality of digitized time points, and reconstructing a series of time resolved MR images, each image of the series of MR images at one specific time point selected from the plurality of digitized time points for each phase-encoded step. Each image in the series of time-resolved MR images corresponding to a specific time point in a cyclic event.

Abstract: A method for verifying the brake force of an electromagnetic elevator brake includes the steps of closing the brake, supplying electrical current to the brake up to a preset verification level and determining whether there has been any movement of the elevator car being braked.

Abstract: The present disclosure provides a staged-retention method for upstream production of biomacromolecules, a production module used therein, and an application of the method/module in the industrial production of polypeptides, fusion proteins and immunoglobulin molecules. The method of the present disclosure can effectively improve the upstream production efficiency, yield and purity in the large-scale production of a recombinant protein.

Abstract: The disclosed apparatus, systems and methods relate to the delivery of personalized nutraceutical products to a subject, comprising a library of actives; a software module; and a dispensing unit. In certain aspects, the system further comprises a packaging unit and a delivery unit. According to certain aspects, the library of actives comprises a plurality of active nutraceutical ingredients formulated for precise dispensing. In further aspects, the software module is constructed and arranged to receive prescription information for the subject and to output dispensing instructions to the dispensing unit. In still further aspects, the dispensing unit is constructed and arranged to receive dispensing instructions from the software module and to dispense one or more actives from the library of actives to form a nutraceutical product, and wherein the dispensing instructions are derived from the prescription information and customized to the nutritional needs of the subject.

Abstract: A method for survey data processing compensates for visco-acoustic effects in TTI medium in an RTM method. This method employs propagating in conjugate medium to yield correct phase, and acoustic wave propagation to yield correct amplitudes through adaptive matching filtering.

Abstract: Conjugated diene monovinylarene block copolymers containing an internal conjugated diene block and having superior kink resistance properties are disclosed. These copolymers can be used to produce tubing and other end-use articles, and can be a replacement for flexible PVC.

Abstract: The present invention provides an anthropogenic glucagon-like peptide-1 (GLP-1) recombinant protein molecule fused with an anthropogenic immunoglobulin subtype (IgG2) Fc section and a preparation method and purpose thereof. The fusion protein has the biological activity of GLP-1, and also has a significantly prolonged half-life in vivo. The fusion protein can be used to treat type II diabetes, obesity, and other diseases that are treated by decreasing serum glucose, suppressing gastrointestinal motility, and emptying or suppressing food intake.

Abstract: A method for verifying the brake force of an electromagnetic elevator brake includes the steps of closing the brake, supplying electrical current to the brake up to a preset verification level and determining whether there has been any movement of the elevator car being braked.

Abstract: Systems and methods provide real time custom audio in accordance with embodiments of the invention. One method includes selecting a video stream from source multimedia content using a media server; recording a voice-over session audio recording for the video stream using the media server, where the voice-over session audio recording comprises real time custom audio for the video stream; synchronizing the timing of the voice-over session audio recording with the video stream to create a voice-over stream using the media server; and storing the voice-over stream as at least one voice-over audio stream for the source video channel using the media server.

Abstract: Described herein is combination of flocculants for flocculating fines solids in a suspension thereof. The combination includes: (a) an anionic polymer flocculant, and (b) a charged particle-polymer hybrid flocculant that includes charged core particles having an average size between about 150 nm and about 800 nm and each having a polymer polymerized thereon. The anionic polymer flocculant is to be added before, or at substantially the same time as, the charged particle-polymer hybrid flocculant.

Abstract: Conjugated diene monovinylarene block copolymers containing an internal conjugated diene block and having superior kink resistance properties are disclosed. These copolymers can be used to produce tubing and other end-use articles, and can be a replacement for flexible PVC.

Abstract: Representative methods and systems are disclosed for reducing image distortion or increasing spatial resolution in echo planar magnetic resonance imaging. In representative embodiments, a targeted field of view (FOV) image is divided into segments, with each segment having a predetermined overlap region with an adjacent segment, such as in a phase-encoding direction. Image data is acquired for each segment, sequentially or simultaneously, using a reduced phase-encoding FOV with a 2D radiofrequency (RF) excitation pulse, and rotated and scaled magnetic field gradients. The 2D RF excitation pulse may also be modulated, such as onto a plurality of different carrier frequencies, for simultaneous acquisition of multiple segments in the same imaging plane. Using the spatial response of the 2D RF excitation pulse, the acquired image data for each segment of the plurality of segments is combined to generate a combined magnetic resonance image having the targeted field of view.

Abstract: Conjugated diene monovinylarene block copolymers containing an internal conjugated diene block and having superior kink resistance properties are disclosed. These copolymers can be used to produce tubing and other end-use articles, and can be a replacement for flexible PVC.