Patents by Inventor JOEL COLLIER

JOEL COLLIER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TABLETIZATION OF PEPTIDE SELF-ASSEMBLIES AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20220362159
    Abstract: The present disclosure provides, in part, peptide self-assemblies that are made into tablet form and methods of making and using the same. In some embodiments, the disclosure provides methods and formulations for a tabletized form of a vaccine, particularly a vaccine comprising self-assembling peptide-polymer nanofibers, an excipient and an adjuvant. Methods of making and using the tablet formulation are also provided.
    Type: Application
    Filed: September 28, 2020
    Publication date: November 17, 2022
    Inventors: Joel COLLIER, Sean KELLY
  • SUPRAMOLECULAR POLYPEPTIDE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20220194989
    Abstract: The present disclosure provides a supramolecular (self-assembling) polypeptide complex that comprises a plurality of randomized polyamino acids that self-assemble into nanofibers and methods of making and using same.
    Type: Application
    Filed: May 4, 2020
    Publication date: June 23, 2022
    Inventors: Joel COLLIER, Nicole VOTAW
  • COMPOSITIONS COMPRISING SUPRAMOLECULAR NANOFIBER HIV ENVELOPES AND METHODS FOR THEIR USE
    Publication number: 20220040290
    Abstract: The technology provides immunogenic compositions comprising HIV-1 envelopes in supramolecular nanofiber complexes, which may also comprise a T-cell helper epitopes, and methods of using these compositions for induction of immune responses.
    Type: Application
    Filed: September 24, 2019
    Publication date: February 10, 2022
    Inventors: Sallie PERMAR, Joel COLLIER, Kevin O. SAUNDERS, Chelsea FRIES, Fouda Amou'ou Genevieve GINY
  • METHODS AND COMPOSITIONS INVOLVING FIBRILLIZING POLYPEPTIDES FOR NANOFIBERS
    Publication number: 20160074488
    Abstract: Embodiments of the invention are directed to fibrillar adjuvants. For example, epitopes assembled by a synthetic peptide domain into nanofibers comprising a ?-fibrillization peptide may elicit high antibody titers in the absence of any adjuvant. In certain embodiments, multiple different antigens may be integrated into polypeptide nanofibers, providing biomaterials with modular and precise composition of bioactive proteins.
    Type: Application
    Filed: November 25, 2015
    Publication date: March 17, 2016
    Inventors: Joel Collier, Gregory Hudalla
  • Methods and compositions involving fibrillizing polypeptides for nanofibers
    Patent number: 9200082
    Abstract: Embodiments of the invention are directed to fibrillar adjuvants. For example, epitopes assembled by a synthetic peptide domain into nanofibers comprising a ?-fibrillization peptide may elicit high antibody titers in the absence of any adjuvant. In certain embodiments, multiple different antigens may be integrated into polypeptide nanofibers, providing biomaterials with modular and precise composition of bioactive proteins.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: December 1, 2015
    Assignee: The University of Chicago
    Inventors: Joel Collier, Gregory Hudalla
  • METHODS AND COMPOSITIONS INVOLVING FIBRILLIZING POLYPEPTIDES FOR NANOFIBERS
    Publication number: 20140273148
    Abstract: Embodiments of the invention are directed to fibrillar adjuvants. For example, epitopes assembled by a synthetic peptide domain into nanofibers comprising a ?-fibrillization peptide may elicit high antibody titers in the absence of any adjuvant. In certain embodiments, multiple different antigens may be integrated into polypeptide nanofibers, providing biomaterials with modular and precise composition of bioactive proteins.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Inventors: JOEL COLLIER, GREGORY HUDALLA