Patents by Inventor Joel Crouzet

Joel Crouzet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6171846
    Abstract: The invention concerns mutant microorganisms blocked in a step of Streptogramin biosynthesis and methods for preparing cells blocked in a step of Streptogramin biosynthesis.
    Type: Grant
    Filed: January 15, 1999
    Date of Patent: January 9, 2001
    Assignee: Aventis Pharma S.A.
    Inventors: Veronique Blanc, Francis Blanche, Joel Crouzet, Nathalie Jacques, Patricia LaCroix, Denis Thibaut, Monique Zagorec, Laurent DeBussche, Valerie De Crecy-Lagard
  • Patent number: 6156545
    Abstract: The present invention relates to a biosynthetic process for preparing cobalamines. More precisely, it relates to a process for amplifying the production of cobalamines and, more specifically, of coenzyme B.sub.12 by means of recombinant DNA techniques and/or by means of adding a novel cobalamine precursor.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: December 5, 2000
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Francis Blanche, Beatrice Cameron, Joel Crouzet, Laurent Debussche, Denis Thibaut, Elisabeth Remy
  • Patent number: 6153597
    Abstract: A pharmaceutical composition useful for nucleic acid transfection is disclosed. The composition contains, in addition to a nucleic acid and at least one transfection agent, at least one compound that combines DNA binding properties with a nuclear DNA vectorisation capability, and preferably belongs to the HMG ("High mobility group") protein family. The use of said composition for in vitro, ex vivo and/or in vivo nucleic acid transfer is also disclosed.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: November 28, 2000
    Assignee: Aventis Pharma S.A.
    Inventors: Francis Blanche, Beatrice Cameron, Joel Crouzet, Vincent Thuillier
  • Patent number: 6143518
    Abstract: Expression plasmids comprising a nucleic acid sequence of interest controlled by a T7 bacteriophage promoter and a stabilizing region comprising all or part of the par region of the RP4 plasmid or a derivative thereof. The invention also concerns the use of said plasmids in the production of recombinant products.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: November 7, 2000
    Assignee: Rhone-Poulenc Rorer SA
    Inventors: Beatrice Cameron, Joel Crouzet
  • Patent number: 6143530
    Abstract: Double-stranded DNA molecules characterised in that they are circular and in that they essentially include one or more genes of interest.
    Type: Grant
    Filed: August 19, 1997
    Date of Patent: November 7, 2000
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Joel Crouzet, Daniel Scherman, Beatrice Cameron, Pierre Wils, Anne-Marie Darquet
  • Patent number: 6077699
    Abstract: Disclosed is the nucleic acid sequences for polypeptides and enzymes involved in the biosynthesis of streptogramins from Streptomyces sp. and the corresponding amino acid sequences. Also disclosed are recombinant vectors and cells as well as methods of making the polypeptides, enzymes and streptogramins using the recombinant host cells.
    Type: Grant
    Filed: August 3, 1995
    Date of Patent: June 20, 2000
    Inventors: Veronique Blanc, Francis Blanche, Joel Crouzet, Nathalie Jacques, Patricia Lacroix, Denis Thibaut, Monique Zagorec, Laurent Debussche, Valerie De Crecy-Lagard
  • Patent number: 6001631
    Abstract: A novel topoisomerase IV, nucleotide sequences coding for said enzyme, corresponding vectors, and the use of said enzyme for screening biologically active materials.
    Type: Grant
    Filed: January 24, 1997
    Date of Patent: December 14, 1999
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Francis Blanche, Beatrice Cameron, Joel Crouzet, Alain Famechon, Lucia Ferrero
  • Patent number: 5891695
    Abstract: The invention concerns nucleotide sequences coding for a polypeptide involved in Streptogramin biosynthesis, recombinant cells containing said sequences, and use thereof.
    Type: Grant
    Filed: May 10, 1995
    Date of Patent: April 6, 1999
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Veronique Blanc, Francis Blanche, Joel Crouzet, Nathalie Jacques, Patricia Lacroix, Denis Thibaut, Monique Zagorec, Laurent Debussche, Valerie De Crecy-Lagard
  • Patent number: 5691163
    Abstract: Cells with an alteration at least in the gene involved in betaine catabolism, their preparation and their use, in particular for producing metabolites and/or enzymes, are disclosed.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: November 25, 1997
    Assignee: Rhone-Poulenc Rorer SA
    Inventors: Beatrice Cameron, Joel Crouzet
  • Patent number: 5670343
    Abstract: The present invention relates to new cloning and/or expression vectors having a broad host range in Gram-negative bacteria, in particular, in the production of recombinant proteins or of metabolites, or in bioconversion reactions, as well as to the host cells containing such vectors.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: September 23, 1997
    Assignee: Rhone Poulenc Biochimie
    Inventors: Beatrice Cameron, Joel Crouzet, Sophie Levy-Schil
  • Patent number: 5635391
    Abstract: The present invention relates to novel polypeptides having a nitrilase activity and to the genetic tools for producing them, namely:the DNA sequence coding for a polypeptide having a nitrilase activity and capable of hydrolyzing nitriles to carboxylates,an analog of this sequence resulting from the degeneracy of the genetic code,a DNA sequence hybridizing with one of these sequences or a fragment thereof and coding for a polypeptide having a nitrilase activity,expression cassettes and microorganisms enabling them to be obtained. Application: enzymatic conversion of nitriles to carboxylates.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 3, 1997
    Assignee: Rhone-Poulenc Chimie
    Inventors: Dominique Petre, Edith Cerbeleaud, Sophie Levy-Schil, Joel Crouzet
  • Patent number: 5629190
    Abstract: The present invention relates to novel polypeptides having a nitrilase activity and to the genetic tools for producing them, namely:the DNA sequence coding for a polypeptide having a nitrilase activity and capable of hydrolyzing nitriles to carboxylates,an analog of this sequence resulting from the degeneracy of the genetic code,a DNA sequence hybridizing with one of these sequences or a fragment thereof and coding for a polypeptide having a nitrilase activity,expression cassettes and microorganisms enabling them to be obtained.Application: enzymatic conversion of nitriles to carboxylates.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: May 13, 1997
    Assignee: Rhone-Poulenc Chimie
    Inventors: Dominique Petre, Edith Cerbeleaud, Sophie Levy-Schil, Joel Crouzet