Abstract: A Metabolic Enhancement Therapy nutritional supplement for treating symptoms and conditions such as acute anxiety, hyperactivity, panic attacks, confusion, involuntary movements, sleep disorders, mood disorders, depression, anger, seizures, obsessive-compulsive behavior, unregulated fear, panic, neuronal disorders, autism, schizophrenia, attention deficit disorder (ADD), attention deficit hyperactive disorder (ADHD) and neuronally based immunologic disorders by administering to a mammal an effective amount of acetyl-L-carnitine, ?-lipoic acid, biotin, vitamin B1, L-glutamine, Vitamin B6, taurine, folinic acid, vitamin B12, trimethylglycine, and L-tryptophan.

Abstract: Compositions and methods are provided for actin regulatory proteins including human severin (H-severin) and H-30; and their uses including the preparation of polyclonal and monoclonal antibodies for use in diagnosing and staging the progression of metastatic tumors and other disorders of cellular growth regulation. Also provided are methods of screening to identify potential drug candidate molecules which modulate the activity of human severin or H-30 and methods of use of such compounds to accelerate wound healing, or to treat a metastasis or growth disorder.

Abstract: Protein compositions and methods of use are provided for human Severin. The uses include the preparation of polyclonal and monoclonal antibodies for diagnosing and staging the progression of metastatic tumors and other disorders of cellular growth regulation. Also provided are methods of screening to identify potential drug candidate molecules which modulate the human Severin activity and methods of use of such compounds to accelerate wound healing, or to treat a metastasis or growth disorder.