Patents by Inventor Joel Dworkin

Joel Dworkin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of delivering antigens for vaccination with a live vector
    Patent number: 6803231
    Abstract: The present invention provides a mutant C. fetus strain in which one or more sapA homologs are altered by an inserted DNA cassette so that the encoded S-layer proteins represent a chimera between the native S-layer proteins and a heterologous peptide encoded by the inserted cassette. Preferably, the heterologous peptide is an immunogen of a pathogen and the mutant strain can be used to immunize a host to develop mucosal and systemic immune responses to such immunogen.
    Type: Grant
    Filed: September 21, 1999
    Date of Patent: October 12, 2004
    Assignee: Vanderbilt University
    Inventors: Martin Blaser, Joel Dworkin, Stuart A. Thompson