Patents by Inventor Joel E. Ranier

Joel E. Ranier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multiplex genomic DNA amplification for deletion detection
    Patent number: 5582989
    Abstract: The present invention relates to a method for detecting multiple DNA sequences simultaneously. The method involves amplification of multiple sequences simultaneously by annealing a plurality of paired oligonucleotide primers to single stranded DNA. One member of each pair is complementary to the sense strand of a sequences and the other member is complementary to a different segment of the anti-sense strand of the same sequence. The amplification occurs by alternately annealing and extending the primers. The invention also includes oligonucleotide primer sequences helpful in detecting genetic diseases and/or exogenous DNA sequences.
    Type: Grant
    Filed: September 30, 1994
    Date of Patent: December 10, 1996
    Assignee: Baylor College of Medicine
    Inventors: Charles T. Caskey, Jeffrey S. Chamberlain, Richard A. L. Gibbs, Joel E. Ranier, Phi N. Nguyen