Patents by Inventor Joel Enas

Joel Enas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing sterile polynucleotide based medicaments
    Patent number: 8435557
    Abstract: The present invention relates to a novel method for producing formulations comprising a polynucleotide, block copolymer and cationic surfactant. The formulations produced by the current method are suitable for use in polynucleotide based medicaments. A suitable method of production disclosed herein additionally comprises cold filtering a mixture of a polynucleotide, block copolymer and cationic surfactant, thereby sterilizing the formulation. The method of the present invention also eliminates the need for thermal cycling of the formulation, thereby reducing the time and expense required to produce large quantities of a formulation during commercial manufacturing. The present invention also relates to novel cationic lipids.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: May 7, 2013
    Assignee: Vical Incorporated
    Inventors: Joel Enas, Andrew Geall
  • Method for Producing Sterile Polynucleotide Based Medicaments
    Publication number: 20080287387
    Abstract: The present invention relates to a novel method for producing formulations comprising a polynucleotide, block copolymer and cationic surfactant. The formulations produced by the current method are suitable for use in polynucleotide based medicaments. A suitable method of production disclosed herein additionally comprises cold filtering a mixture of a polynucleotide, block copolymer and cationic surfactant, thereby sterilizing the formulation. The method of the present invention also eliminates the need for thermal cycling of the formulation, thereby reducing the time and expense required to produce large quantities of a formulation during commercial manufacturing. The present invention also relates to novel cationic lipids.
    Type: Application
    Filed: April 25, 2008
    Publication date: November 20, 2008
    Applicant: Vical Incorporated
    Inventors: Joel Enas, Andrew Geall
  • Method for producing sterile polynucleotide based medicaments
    Patent number: 7381422
    Abstract: The present invention relates to a novel method for producing formulations comprising a polynucleotide, block copolymer and cationic surfactant. The formulations produced by the current method are suitable for use in polynucleotide based medicaments. A suitable method of production disclosed herein additionally comprises cold filtering a mixture of a polynucleotide, block copolymer and cationic surfactant, thereby sterilizing the formulation. The method of the present invention also eliminates the need for thermal cycling of the formulation, thereby reducing the time and expense required to produce large quantities of a formulation during commercial manufacturing. The present invention also relates to novel cationic lipids.
    Type: Grant
    Filed: December 2, 2003
    Date of Patent: June 3, 2008
    Assignee: Vical Incorporated
    Inventors: Joel Enas, Andrew Geall
  • Method for producing sterile polynucleotide based medicaments
    Publication number: 20040162256
    Abstract: The present invention relates to a novel method for producing formulations comprising a polynucleotide, block copolymer and cationic surfactant. The formulations produced by the current method are suitable for use in polynucleotide based medicaments. A suitable method of production disclosed herein additionally comprises cold filtering a mixture of a polynucleotide, block copolymer and cationic surfactant, thereby sterilizing the formulation. The method of the present invention also eliminates the need for thermal cycling of the formulation, thereby reducing the time and expense required to produce large quantities of a formulation during commercial manufacturing. The present invention also relates to novel cationic lipids.
    Type: Application
    Filed: December 2, 2003
    Publication date: August 19, 2004
    Applicant: Vical Incorporated.
    Inventors: Andrew Geall, Joel Enas