Abstract: The present disclosure relates to compositions, methods, mixtures, and kits for detecting the presence of and for removing, a virus from a product produced in an insect cell. The disclosure also relates to proteins, peptides, polypeptides, drug substances, biological products, vaccine antigens, and virus-like particles that are produced in an insect cell and that are free or substantially free of a virus. The disclosure also relates to compositions, methods, assays, and kits for detecting a rhabdovirus in a sample.

Abstract: A combustor is configured to operate in a rotating detonation mode and a deflagration mode. The combustor includes a housing and at least one initiator. The housing defines at least one combustion chamber and is configured for a deflagration process to occur within the at least one combustion chamber during operation in the deflagration mode and a rotating detonation process to occur within the at least one combustion chamber during operation in the rotating detonation mode. The at least one initiator is configured to initiate the rotating detonation process within the at least one combustion chamber during operation in the rotating detonation mode and to initiate the deflagration process within the at least one combustion chamber during operation in the deflagration mode.

Abstract: A turbine engine includes at least one compressor configured to increase pressure of a fluid flow and a primary combustor coupled in flow communication with the at least one compressor. The primary combustor is configured to receive pressurized fluid flow from the at least one compressor. The primary combustor includes a housing defining at least one combustion chamber. The primary combustor is configured for a rotating detonation process to occur within said at least one combustion chamber. The turbine engine also includes at least one supplemental combustor coupled in flow communication with the primary combustor. The at least one supplemental combustor is configured to receive combustion products and perform a combustion operation. The turbine engine further includes a turbine assembly coupled in flow communication with the at least one supplemental combustor. The turbine assembly is configured to receive combustion products from the at least one supplemental combustor.

Abstract: A combustor is configured to operate in a rotating detonation mode and a deflagration mode. The combustor includes a housing and at least one initiator. The housing defines at least one combustion chamber and is configured for a deflagration process to occur within the at least one combustion chamber during operation in the deflagration mode and a rotating detonation process to occur within the at least one combustion chamber during operation in the rotating detonation mode. The at least one initiator is configured to initiate the rotating detonation process within the at least one combustion chamber during operation in the rotating detonation mode and to initiate the deflagration process within the at least one combustion chamber during operation in the deflagration mode.

Abstract: An apparatus and method for the distillation of ocean and brackish water that includes a means for using the ambient temperatures of seawater and air to continually transfer the heat energy, from the outer perimeters of the system, back into the, centrally located, evaporation chamber and insulation for preventing heat from escaping to the atmosphere. The insulation comprises a first and second wall surrounding the basic assemblies of a desalination system in which the space between the first and second wall is under low partial vacuum and is partially filled with an insulation material for structural support. The system provides a feed through means that prevent heat transfer through the structural connections between the first and second walls. The system provides an evaporation system for flash evaporation by atomizing the input contaminated water, preheated by the heat of condensation into very small liquid droplets, which are then sprayed into a stream of hot dry air.

Abstract: An apparatus and method for the distillation of ocean and brackish water that includes a means for using the ambient temperatures of seawater and air to continually transfer the heat energy, from the outer perimeters of the system, back into the, centrally located, evaporation chamber and insulation for preventing heat from escaping to the atmosphere. The insulation comprises a first and second wall surrounding the basic assemblies of a desalination system in which the space between the first and second wall is under low partial vacuum and is partially filled with an insulation material for structural support. The system provides a feed through means that prevent heat transfer through the structural connections between the first and second walls. The system provides an evaporation system for flash evaporation by atomizing the input contaminated water, preheated by the heat of condensation into very small liquid droplets, which are then sprayed into a stream of hot dry air.

Abstract: The present invention provides polypeptides having a composite amino acid sequence derived from a consensus sequence representing the capsid proteins of two or more circulating strains of a non-enveloped virus. In particular, the invention provides virus-like particles comprising at least one composite polypeptide. Such virus-like particles have antigenic epitopes of two or more circulating strains of a non-enveloped virus and produce an increase in antisera cross-reactivity to one or more circulating strains of the non-enveloped virus. Methods of making composite virus-like particles and vaccine formulations comprising composite virus-like particles are also disclosed.

Abstract: An apparatus and method for the distillation of ocean and brackish water that includes insulation for preventing heat from escaping to the atmosphere is disclosed. The insulation comprises a second wall surrounding the basic assemblies of a desalination system in which the space between the second wall and basic assemblies is under low partial vacuum and is partially or totally filled with an insulation material for structural support. The system allows for flash evaporation of heated input water and condensing the resultant vapors into pure distilled water. The heat of condensation as well as heat from the salt byproduct may be recaptured and used to preheat the input contaminated water.

Abstract: The present disclosure relates to compositions, methods, mixtures, and kits for detecting the presence of and for removing, a virus from a product produced in an insect cell. The disclosure also relates to proteins, peptides, polypeptides, drug substances, biological products, vaccine antigens, and virus-like particles that are produced in an insect cell and that are free or substantially free of a virus. The disclosure also relates to compositions, methods, assays, and kits for detecting a rhabdovirus in a sample.

Abstract: The present invention provides polypeptides having a composite amino acid sequence derived from a consensus sequence representing the capsid proteins of two or more circulating strains of a non-enveloped virus. In particular, the invention provides virus-like particles comprising at least one composite polypeptide. Such virus-like particles have antigenic epitopes of two or more circulating strains of a non-enveloped virus and produce an increase in antisera cross-reactivity to one or more circulating strains of the non-enveloped virus. Methods of making composite virus-like particles and vaccine formulations comprising composite virus-like particles are also disclosed.

Abstract: The present invention provides polypeptides having a composite amino acid sequence derived from a consensus sequence representing the capsid proteins of two or more circulating strains of a non-enveloped virus. In particular, the invention provides virus-like particles comprising at least one composite polypeptide. Such virus-like particles have antigenic epitopes of two or more circulating strains of a non-enveloped virus and produce an increase in antisera cross-reactivity to one or more circulating strains of the non-enveloped virus. Methods of making composite virus-like particles and vaccine formulations comprising composite virus-like particles are also disclosed.

Abstract: The present application provides an optical probe system for use with a combustion flame in a combustion chamber. The optical probe system may include a number of optical probes fixedly attached about the combustion chamber and positioned such that the optical probes collect light generated by the combustion flame in a field of view of each of the optical probes. One or more components external to the combustion chamber may produce and analyze signals indicative of the light generated by the combustion flame in the field of view of each of the optical probes.

Abstract: An apparatus and method for the distillation of ocean and brackish water that includes insulation means for preventing heat from escaping to the atmosphere is disclosed. The insulation means comprises a second wall surrounding the basic assemblies of a desalination system in which the space between the second wall and basic assemblies is under low partial vacuum and is partially or totally filled with an insulation material for structural support. The system provides a means for flash evaporation of heated input water and condensing the resultant vapors into pure distilled water. A means for recapturing and using the heat of condensation as well as heat from the salt byproduct to preheat the input contaminated water is also disclosed.

Abstract: The present invention provides polypeptides having a composite amino acid sequence derived from a consensus sequence representing the capsid proteins of two or more circulating strains of a non-enveloped virus. In particular, the invention provides virus-like particles comprising at least one composite polypeptide. Such virus-like particles have antigenic epitopes of two or more circulating strains of a non-enveloped virus and produce an increase in antisera cross-reactivity to one or more circulating strains of the non-enveloped virus. Methods of making composite virus-like particles and vaccine formulations comprising composite virus-like particles are also disclosed.

Abstract: An improved fluid flow sensor comprising a housing with a fluid inlet and fluid outlet, a valve chamber connected to the fluid inlet, and a movable valve body wherein the valve body moves between a first position, blocking a first outlet in the valve chamber, and a second position blocking a second outlet in the valve chamber; the first outlet of the valve chamber connected to an inlet at the first end of a measuring chamber, and the second outlet of the valve chamber connected to an inlet at the second end of the measuring chamber, with a movable measuring body located in the measuring chamber capable of moving between the first and second ends of the measuring chamber, and the measuring chamber having outlets at the first and second ends, so that the movable bodies switch position in tandem as fluid flows through the system.

Abstract: A premixed partial oxidation (POx) syngas generator is provided. The syngas generator includes a premixing device configured to mix a fuel stream and oxygen in a premixing region to form a gaseous pre-mix. The premixing device includes a fuel inlet configured to introduce the fuel stream within the premixing device and a flow conditioning device configured to pre-condition the fuel stream. The premixing device also includes an oxygen inlet configured to introduce oxygen into the fuel stream to facilitate premixing of the fuel stream and oxygen in the premixing region located downstream of the flow conditioning device. The syngas generator also includes a combustion chamber configured to combust the gaseous pre-mix from the premixing device to produce a synthesis gas enriched with carbon monoxide and hydrogen gas.

Abstract: A combustor nozzle is provided. The combustor nozzle includes a first fuel system configured to introduce a hydrocarbon fuel into a combustion chamber to enable lean premixed combustion within the combustion chamber and a second fuel system configured to introduce a syngas fuel, a hydrocarbon fuel and diluents into the combustion chamber to enable diffusion combustion within the combustion chamber.

Abstract: In accordance with certain embodiments, a system includes a fuel-air injection mechanism having coaxial fuel and air passages leading to fuel and air injection openings. The fuel and air injection openings are configured to reside at an off-axis position of a gas turbine combustor, and the fuel and air injection openings are configured to orient in an injection direction not aligned with a flow direction through the gas turbine combustor to a turbine.

Abstract: In accordance with certain embodiments, a system includes a counterflow injection mechanism. The counterflow injection mechanism includes a fuel-air injection mechanism having fuel and air passages leading to fuel and air injection openings, wherein the fuel and air injection openings are disposed at an off-center position and a generally counterflow direction relative to a generally lengthwise flow axis of a gas turbine combustor.

Abstract: A multi-stage combustion fuel reformer (20) wherein heat energy from a leaner-burning stage (22) is used to accelerate the fuel reforming kinetics of a richer-burning stage (28). The two stages may be axially arranged (36) or radially arranged (50) with respect to each other. Both stages (64, 66) may utilize gas-phase combustion; or both stages (78, 82) may utilized catalytic combustion; or both gas-phase ((90) and catalytic combustion (92) may be used together. The multi-stage reformer (112) may form part of a gas-to-liquid fuel reforming system (110).