Patents by Inventor Joel Kaar

Joel Kaar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Distributed Ribonucleic Acid Manufacturing Via Enzymatic Reaction And Separation
    Publication number: 20240026408
    Abstract: Systems, comprising: an aqueous medium, the aqueous medium having an amount of DNA disposed therein, the aqueous medium having one or more RNA polymerases disposed therein; and a non-aqueous medium. Methods, the methods comprising operating a system according to the present disclosure, so as to give rise to an RNA product disposed in the non-aqueous medium. Methods, comprising: with an RNA polymerase in an aqueous medium, effecting synthesis of an RNA product from template DNA, and selectively transferring the RNA product to a non-aqueous medium.
    Type: Application
    Filed: July 20, 2023
    Publication date: January 25, 2024
    Inventors: Daeyeon Lee, Masoud Soroush, Joel Kaar, Dimitrios Papavassiliou, Kathleen J Stebe
  • Devices, systems and methods for reducing the concentration of a chemical entity in fluids
    Patent number: 8323379
    Abstract: A method of improving the blood compatibility of a blood-contacting surface includes immobilizing carbonic anhydrase on the surface, wherein the surface exhibits carbonic anhydrase activity of at least 20% of maximum theoretical activity of the surface based on monolayer surface coverage of carbonic anhydrase.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: December 4, 2012
    Assignee: University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: William J. Federspiel, Alan J. Russell, Heung-Il Oh, Joel Kaar
  • Devices, systems and methods for reducing the concentration of a chemical entity in fluids
    Patent number: 8043411
    Abstract: A device for removal of at least a portion of carbon dioxide from an aqueous fluid includes at least one membrane through which carbon dioxide can pass to be removed from the fluid and immobilized carbonic anhydrase on or in the vicinity of a first surface of the membrane to be contacted with the fluid such that the immobilized carbonic anhydrase comes into contact with the fluid. The first surface exhibits carbonic anhydrase activity of at least 20% of maximum theoretical activity of the first surface of the membrane based on monolayer surface coverage of carbonic anhydrase in the case that the carbonic anhydrase is immobilize on the first surface.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: October 25, 2011
    Assignee: University of Pittsburgh - of the Commonwealth System of Higher Education
    Inventors: William J. Federspiel, Allan J. Russell, Heung-Il Oh, Joel Kaar
  • Devices, systems and methods for reducing the concentration of a chemical entity in fluids
    Publication number: 20080014622
    Abstract: A device for removal of at least a portion of carbon dioxide from an aqueous fluid includes at least one membrane through which carbon dioxide can pass to be removed from the fluid and immobilized carbonic anhydrase on or in the vicinity of a first surface of the membrane to be contacted with the fluid such that the immobilized carbonic anhydrase comes into contact with the fluid. The first surface exhibits carbonic anhydrase activity of at least 20% of maximum theoretical activity of the first surface of the membrane based on monolayer surface coverage of carbonic anhydrase in the case that the carbonic anhydrase is immobilize on the first surface.
    Type: Application
    Filed: June 8, 2007
    Publication date: January 17, 2008
    Inventors: William Federspiel, Alan Russell, Heung-II Oh, Joel Kaar