Patents by Inventor Joel Kline
Joel Kline has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8158592Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: GrantFiled: January 7, 2005Date of Patent: April 17, 2012Assignees: Coley Pharmaceutical Group, Inc., The United States of America, as represented by the Department of Health and Human Services, University of Iowa Research FoundationInventors: Arthur M. Krieg, Joel Kline, Dennis Klinman, Alfred D. Steinberg
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Patent number: 8058249Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: GrantFiled: July 16, 2004Date of Patent: November 15, 2011Assignees: University of Iowa Research Foundation, United States of America as represented by the Department of Health and Human Services, Coley Pharmaceutical Group, Inc.Inventors: Arthur M. Krieg, Joel Kline, Dennis Klinman, Alfred D. Steinberg
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Patent number: 7723500Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: GrantFiled: August 11, 2006Date of Patent: May 25, 2010Assignees: University of Iowa Research Foundation, The United States of America as represented by the Department of Health and Human Services, Coley Pharmaceutical Group, Inc.Inventors: Arthur M. Krieg, Joel Kline, Dennis Klinman, Alfred D. Steinberg
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Publication number: 20080031936Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: November 10, 2006Publication date: February 7, 2008Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., U.S.A., as represented by the Secretary, Dept. of Health and Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20080026011Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: June 5, 2007Publication date: January 31, 2008Applicants: University of Iowa Research Foundation, The US, as represented by the Department of Health and Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman
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Publication number: 20070078104Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: September 22, 2006Publication date: April 5, 2007Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc.Inventors: Arthur Krieg, Joel Kline
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Publication number: 20070066553Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: August 11, 2006Publication date: March 22, 2007Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20060089326Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: December 7, 2005Publication date: April 27, 2006Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20060003955Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: February 25, 2005Publication date: January 5, 2006Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary Department of Health & Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20050277609Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: January 7, 2005Publication date: December 15, 2005Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., The USA, as represented by the Secretary, Department of Health & Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20050267064Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: May 23, 2005Publication date: December 1, 2005Applicants: University of Iowa Research Foundation, United States of America, as represented by the Secretary Department of Health and Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman
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Publication number: 20050233995Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: April 23, 2004Publication date: October 20, 2005Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health & Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20050215500Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: October 22, 2004Publication date: September 29, 2005Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Dept. of Health & Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20050123523Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: August 26, 2004Publication date: June 9, 2005Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health & Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20050101557Abstract: Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.Type: ApplicationFiled: August 18, 2004Publication date: May 12, 2005Applicant: The University of Iowa Research FoundationInventors: Arthur Krieg, Joel Kline
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Publication number: 20050070491Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: July 3, 2003Publication date: March 31, 2005Applicants: University of Iowa Research FoundationInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20050059625Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: July 2, 2004Publication date: March 17, 2005Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary Department of Health & Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20050054602Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: July 16, 2004Publication date: March 10, 2005Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health & Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20050049215Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: July 9, 2004Publication date: March 3, 2005Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health & Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
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Publication number: 20050049216Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.Type: ApplicationFiled: July 16, 2004Publication date: March 3, 2005Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as a represented by the Secretary, Department of Health & Human ServicesInventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg