Patents by Inventor Joel Kline

Joel Kline has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8158592
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Grant
    Filed: January 7, 2005
    Date of Patent: April 17, 2012
    Assignees: Coley Pharmaceutical Group, Inc., The United States of America, as represented by the Department of Health and Human Services, University of Iowa Research Foundation
    Inventors: Arthur M. Krieg, Joel Kline, Dennis Klinman, Alfred D. Steinberg
  • Patent number: 8058249
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: November 15, 2011
    Assignees: University of Iowa Research Foundation, United States of America as represented by the Department of Health and Human Services, Coley Pharmaceutical Group, Inc.
    Inventors: Arthur M. Krieg, Joel Kline, Dennis Klinman, Alfred D. Steinberg
  • Patent number: 7723500
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Grant
    Filed: August 11, 2006
    Date of Patent: May 25, 2010
    Assignees: University of Iowa Research Foundation, The United States of America as represented by the Department of Health and Human Services, Coley Pharmaceutical Group, Inc.
    Inventors: Arthur M. Krieg, Joel Kline, Dennis Klinman, Alfred D. Steinberg
  • Publication number: 20080031936
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: November 10, 2006
    Publication date: February 7, 2008
    Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., U.S.A., as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20080026011
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: June 5, 2007
    Publication date: January 31, 2008
    Applicants: University of Iowa Research Foundation, The US, as represented by the Department of Health and Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman
  • Publication number: 20070078104
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: September 22, 2006
    Publication date: April 5, 2007
    Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc.
    Inventors: Arthur Krieg, Joel Kline
  • Publication number: 20070066553
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: August 11, 2006
    Publication date: March 22, 2007
    Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20060089326
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: December 7, 2005
    Publication date: April 27, 2006
    Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20060003955
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: February 25, 2005
    Publication date: January 5, 2006
    Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary Department of Health & Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20050277609
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: January 7, 2005
    Publication date: December 15, 2005
    Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., The USA, as represented by the Secretary, Department of Health & Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20050267064
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: May 23, 2005
    Publication date: December 1, 2005
    Applicants: University of Iowa Research Foundation, United States of America, as represented by the Secretary Department of Health and Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman
  • Publication number: 20050233995
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: April 23, 2004
    Publication date: October 20, 2005
    Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20050215500
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: October 22, 2004
    Publication date: September 29, 2005
    Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Dept. of Health & Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20050123523
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: August 26, 2004
    Publication date: June 9, 2005
    Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20050101557
    Abstract: Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.
    Type: Application
    Filed: August 18, 2004
    Publication date: May 12, 2005
    Applicant: The University of Iowa Research Foundation
    Inventors: Arthur Krieg, Joel Kline
  • Publication number: 20050070491
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: July 3, 2003
    Publication date: March 31, 2005
    Applicants: University of Iowa Research Foundation
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20050059625
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: July 2, 2004
    Publication date: March 17, 2005
    Applicants: University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary Department of Health & Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20050054602
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: July 16, 2004
    Publication date: March 10, 2005
    Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20050049216
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: July 16, 2004
    Publication date: March 3, 2005
    Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as a represented by the Secretary, Department of Health & Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg
  • Publication number: 20050049215
    Abstract: Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.
    Type: Application
    Filed: July 9, 2004
    Publication date: March 3, 2005
    Applicants: The University of Iowa Research Foundation, Coley Pharmaceutical Group, Inc., United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Arthur Krieg, Joel Kline, Dennis Klinman, Alfred Steinberg