Patents by Inventor Joel Lazewatsky
Joel Lazewatsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230270412Abstract: Provided herein are methods and devices for identifying and/or distinguishing UCA formulations and specifically activating such formulations to produce UCA suitable for in vivo use.Type: ApplicationFiled: August 3, 2021Publication date: August 31, 2023Applicant: Lantheus Medical Imaging, Inc.Inventor: Joel Lazewatsky
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Publication number: 20220017459Abstract: The present invention generally relates to novel synthetic methods, systems, kits, salts, and precursors useful in medical imaging. In some embodiments, the present invention provides compositions comprising an imaging agent precursor, which may be formed using the synthetic methods described herein. An imaging agent may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18F. In some cases, an imaging agent including salt forms (e.g., ascorbate salt) may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.Type: ApplicationFiled: July 28, 2021Publication date: January 20, 2022Applicant: Lantheus Medical Imaging, Inc.Inventors: Ajay Purohit, Pedro Benites, Heike S. Radeke, Joel Lazewatsky, L. Veronica Lee
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Patent number: 11174223Abstract: The present invention generally relates to novel synthetic methods, systems, kits, salts, and precursors useful in medical imaging. In some embodiments, the present invention provides compositions comprising an imaging agent precursor, which may be formed using the synthetic methods described herein. An imaging agent may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18F. In some cases, an imaging agent including salt forms (e.g., ascorbate salt) may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.Type: GrantFiled: May 12, 2017Date of Patent: November 16, 2021Assignee: Lantheus Medical Imaging, Inc.Inventors: Ajay Purohit, Pedro Benites, Heike S. Radeke, Joel Lazewatsky, L. Veronica Lee
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Publication number: 20200171177Abstract: Provided herein are methods and devices for identifying and/or distinguishing UCA formulations and specifically activating such formulations to produce UCA suitable for in vivo use.Type: ApplicationFiled: February 3, 2020Publication date: June 4, 2020Applicant: Lantheus Medical Imaging, Inc.Inventors: Simon P. Robinson, Carol Walker, David C. Onthank, Joel Lazewatsky, Nhung Tuyet Nguyen
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Patent number: 10588988Abstract: Provided herein are methods and devices for identifying and/or distinguishing UCA formulations and specifically activating such formulations to produce UCA suitable for in vivo use.Type: GrantFiled: September 3, 2019Date of Patent: March 17, 2020Assignee: Lantheus Medical Imaging, Inc.Inventors: Simon P. Robinson, Carol Walker, David C. Onthank, Joel Lazewatsky, Nhung Tuyet Nguyen
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Publication number: 20200000943Abstract: Provided herein are methods and devices for identifying and/or distinguishing UCA formulations and specifically activating such formulations to produce UCA suitable for in vivo use.Type: ApplicationFiled: September 3, 2019Publication date: January 2, 2020Applicant: Lantheus Medical Imaging, Inc.Inventors: Simon P. Robinson, Carol Walker, David C. Onthank, Joel Lazewatsky, Nhung Tuyet Nguyen
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Patent number: 10245332Abstract: The present invention is directed, in part, to compounds and methods for imaging the central nervous system or cancer, comprising administering to a subject a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the subject using diagnostic imaging.Type: GrantFiled: May 12, 2016Date of Patent: April 2, 2019Assignee: Lantheus Medical Imaging, Inc.Inventors: Simon P. Robinson, David S. Casebier, Ming Yu, Mikhail Kagan, Joel Lazewatsky
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Patent number: 10022462Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.Type: GrantFiled: February 15, 2017Date of Patent: July 17, 2018Assignee: Lantheus Medical Imaging, Inc.Inventors: Richard R. Cesati, Edward H. Cheesman, Joel Lazewatsky, Heike S. Radeke, Enrico Mongeau, Dianne D. Zdankiewicz, Marybeth Devine
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Publication number: 20180133347Abstract: The present invention is directed, in part, to compounds and methods for imaging the central nervous system or cancer, comprising administering to a subject a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the subject using diagnostic imaging.Type: ApplicationFiled: May 12, 2016Publication date: May 17, 2018Applicant: Lantheus Medical Imaging, Inc.Inventors: Simon P. Robinson, David S. Casebier, Ming Yu, Mikhail Kagan, Joel Lazewatsky
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Publication number: 20170355669Abstract: The present invention generally relates to novel synthetic methods, systems, kits, salts, and precursors useful in medical imaging. In some embodiments, the present invention provides compositions comprising an imaging agent precursor, which may be formed using the synthetic methods described herein. An imaging agent may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18F. In some cases, an imaging agent including salt forms (e.g., ascorbate salt) may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.Type: ApplicationFiled: May 12, 2017Publication date: December 14, 2017Applicant: Lantheus Medical Imaging, Inc.Inventors: Ajay Purohit, Pedro Benites, Heike S. Radeke, Joel Lazewatsky, L. Veronica Lee
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Publication number: 20170319718Abstract: Provided herein are methods and devices for identifying and/or distinguishing UCA formulations and specifically activating such formulations to produce UCA suitable for in vivo use.Type: ApplicationFiled: May 4, 2017Publication date: November 9, 2017Applicant: Lantheus Medical Imaging, Inc.Inventors: Simon P. Robinson, Carol Walker, David C. Onthank, Joel Lazewatsky, Nhung Tuyet Nguyen
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Publication number: 20170258947Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.Type: ApplicationFiled: February 15, 2017Publication date: September 14, 2017Applicant: Lantheus Medical Imaging, Inc.Inventors: Richard R. Cesati, Edward H. Cheesman, Joel Lazewatsky, Heike S. Radeke, Enrico Mongeau, Dianne D. Zdankiewicz, Marybeth Devine
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Patent number: 9603951Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.Type: GrantFiled: December 5, 2014Date of Patent: March 28, 2017Assignee: Lantheus Medical Imaging, Inc.Inventors: Joel Lazewatsky, Marybeth Devine
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Publication number: 20160361448Abstract: The present invention is directed, in part, to compounds and methods for imaging the central nervous system or cancer, comprising administering to a subject a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the subject using diagnostic imaging.Type: ApplicationFiled: May 12, 2016Publication date: December 15, 2016Applicant: Lantheus Medical Imaging, Inc.Inventors: Simon P. Robinson, David S. Casebier, Ming Yu, Mikhail Kagan, Joel Lazewatsky
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Patent number: 9408927Abstract: The present invention is directed, in part, to compounds and methods for imaging the central nervous system or cancer, comprising administering to a subject a contrast agent which comprises a compound that binds MC-I, and an imaging moiety, and scanning the subject using diagnostic imaging.Type: GrantFiled: February 27, 2009Date of Patent: August 9, 2016Assignee: Lantheus Medical Imaging, Inc.Inventors: Simon P. Robinson, David S. Casebier, Ming Yu, Mikhail Kagan, Joel Lazewatsky
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Patent number: 9388125Abstract: The present invention generally relates to novel synthetic methods, systems, kits, salts, and precursors useful in medical imaging. In some embodiments, the present invention provides compositions comprising an imaging agent precursor, which may be formed using the synthetic methods described herein. An imaging agent may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18F. In some cases, an imaging agent including salt forms (e.g., ascorbate salt) may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.Type: GrantFiled: May 11, 2011Date of Patent: July 12, 2016Assignee: Lantheus Medical Imaging, Inc.Inventors: Ajay Purohit, Pedro Benites, Edward H. Cheesman, Joel Lazewatsky, L. Veronica Lee, Richard R. Cesati, Richard J. Looby, Heike S. Radeke
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Publication number: 20150165074Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.Type: ApplicationFiled: December 5, 2014Publication date: June 18, 2015Applicant: Lantheus Medical Imaging, Inc.Inventors: Joel Lazewatsky, Marybeth Devine
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Patent number: 8936777Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.Type: GrantFiled: February 8, 2011Date of Patent: January 20, 2015Assignee: Lantheus Medical Imaging, Inc.Inventors: Richard R. Cesati, Edward H. Cheesman, Joel Lazewatsky, Heike S. Radeke, Enrico Mongeau, Dianne D. Zdankiewicz, Marybeth Devine
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Publication number: 20130149244Abstract: The present invention generally relates to novel synthetic methods, systems, kits, salts, and precursors useful in medical imaging. In some embodiments, the present invention provides compositions comprising an imaging agent precursor, which may be formed using the synthetic methods described herein. An imaging agent may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18F. In some cases, an imaging agent including salt forms (e.g., ascorbate salt) may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.Type: ApplicationFiled: May 11, 2011Publication date: June 13, 2013Applicant: Lantheus Medical Imaging, Inc.Inventors: Ajay Purohit, Pedro Benites, Edward H. Cheesman, Joel Lazewatsky, L. Veronica Lee, Richard R. Cesati, Richard J. Looby, Heike S. Radeke
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Publication number: 20130064769Abstract: The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.Type: ApplicationFiled: February 8, 2011Publication date: March 14, 2013Applicant: Lantheus Medical Imaging, IncInventors: Richard R. Cesati, Edward H. Cheesman, Joel Lazewatsky, Heike S. Radeke, James F. Castner, Enrico Mongeau, Dianne D. Zdankiewicz, Robert Wilburn Siegler, Marybeth Devine