Patents by Inventor Joel M. Linden

Joel M. Linden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treating inflammatory response
    Patent number: 6232297
    Abstract: Compounds and methods are provided to treat inflammatory conditions with certain A2A adenosine receptor antagonists.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: May 15, 2001
    Assignee: University of Virginia Patent Foundation
    Inventors: Joel M. Linden, Gail W. Sullivan, Ian J. Sarembock, Timothy MacDonald, Mark Okusa
  • 8-phenyl- or 8-cycloalkyl xanthine antagonists of A2B human adenosine receptors
    Patent number: 6117878
    Abstract: The invention concerns the use of 8-phenylxanthines, 8-cyloalkylxanthines or 8- substituted xanthine derivatives to specifically modulate the physiologic role of the A2B adenosine receptor.
    Type: Grant
    Filed: February 24, 1998
    Date of Patent: September 12, 2000
    Assignees: University of Virginia, University of Virginia Patent Foundation
    Inventor: Joel M. Linden
  • Method for improving insulin sensitivity using an adenosine receptor antagonist
    Patent number: 6060481
    Abstract: Methods for improving insulin sensitivity in a patient using one or more A.sub.2B adenosine receptor antagonists are disclosed. These methods stimulate insulin dependent glucose uptake in muscle.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: May 9, 2000
    Assignee: The Penn State Research Foundation
    Inventors: Kathryn F. LaNoue, George H. Crist, Joel M. Linden
  • Method for treating inflammatory diseases with A.sub.2a adenosine receptor agonists
    Patent number: 5877180
    Abstract: Agonists of A.sub.2a adenosine receptors are effective for the treatment of inflammatory diseases.
    Type: Grant
    Filed: July 11, 1994
    Date of Patent: March 2, 1999
    Assignee: University of Virginia Patent Foundation
    Inventors: Joel M. Linden, Gail W. Sullivan
  • Aminobenzlpropranolol and pharmaceutical preparation thereof
    Patent number: 4376125
    Abstract: 1-(p-Amino-.alpha.,.alpha.-dimethylphenethylamino)-3-(1-naphthoxy)-2-propan ol, 1-(p-hydroxy-.alpha.,.alpha.-dimethylphenethylamino)-3-(1-naphthoxy)-2-pro panol, 1-(p-methyl-.alpha.,.alpha.-dimethylphenethylamino)-3-(1-naphthoxy)-2-prop anol, 1-(p-methoxy-.alpha.,.alpha.-dimethylphenethylamino)-3-(1-naphthoxy)-2-pro panol and the pharmaceutically acceptable acid addition salts thereof are effective, long lasting .beta.-adrenergic blocking agents and areas of indication are hypertension, angina pectoris, cardiac arrythmia, and the like.
    Type: Grant
    Filed: November 5, 1980
    Date of Patent: March 8, 1983
    Assignee: University of Virginia Alumni Patents Foundation
    Inventors: Gary Brooker, Wesley L. Terasaki, Joel M. Linden