Abstract: The present disclosure pertains to assemblies, devices and systems for shockwave generation and to methods of using the same.

Abstract: Guide extension catheters and methods of manufacturing and using guide extension catheters are disclosed. An example guide extension catheter may include a distal sheath having a proximal opening, a distal opening, and a central lumen extending therebetween. The guide extension catheter may also include a proximal shaft having an outer diameter smaller than an outer diameter of the distal sheath, the proximal shaft including a distal opening. The guide extension catheter may also include a coupling member for securing the distal sheath to the proximal shaft. The coupling member may include a distal portion attached to the distal sheath and a proximal portion disposed within the distal opening of the proximal shaft.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a proximal shaft having a first outer diameter. A distal sheath may be attached to the proximal shaft and may have a second outer diameter greater than the first outer diameter. A trackable tip member may be attached to the distal sheath and extending distally therefrom. The trackable tip member may define a guidewire lumen therein.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter. The catheter may include an elongate shaft having a proximal end, a distal end, and a lumen extending at least partially between the proximal end and the distal end. The shaft may include an inner layer, a reinforcing member, and an outer layer. The outer layer may include a first section positioned adjacent to the proximal end, a second section disposed distally of the first section, a third section positioned distally of the second section, and a fourth section positioned distally of the third section.

Abstract: An embolic protection system may include a guidewire having a length, at least a portion of the guidewire having a non-circular cross-sectional shape, and an embolic protection device including a mounting sleeve configured to attach the embolic protection device to the portion of the guidewire having the non-circular cross-sectional shape. The mounting sleeve may include a non-circular interior cross-sectional shape and a non-circular exterior cross-sectional shape.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a proximal tubular member having a lumen defined therein. A distal tubular member may be attached to the proximal tubular member. The proximal tubular member may have an outer diameter. The distal tubular member may have an inner diameter. The inner diameter of the distal tubular member may be greater than the outer diameter of the proximal tubular member. A stiffening member may be slidably disposed within the proximal tubular member.

Abstract: Guide extension catheters and methods of manufacturing and using guide extension catheters are disclosed. An example guide extension catheter may include a distal sheath having a proximal opening, a distal opening, and a central lumen extending therebetween. The guide extension catheter may also include a proximal shaft having an outer diameter smaller than an outer diameter of the distal sheath, the proximal shaft including a distal opening. The guide extension catheter may also include a coupling member for securing the distal sheath to the proximal shaft. The coupling member may include a distal portion attached to the distal sheath and a proximal portion disposed within the distal opening of the proximal shaft.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include an elongate tubular member having a proximal region, a distal region, and a slot formed in the tubular member between the proximal region and the distal region. The proximal region of the tubular member may be configured to shift between a first configuration and a collapsed configuration. The guide extension catheter may also include an elongate shaft for shifting the proximal region between the first configuration and the collapsed configuration.

Abstract: A rotational atherectomy device advanceable over a guidewire. The rotational atherectomy device includes a drive shaft rotatably extending through an outer tubular member to rotate a cutting member positioned at a distal end thereof. The rotational atherectomy device further includes an insert positioned within the cutting member for frictional contact with the guidewire.

Abstract: A rotational atherectomy device including a drive shaft rotatably extending through an outer tubular member to rotate a cutting member positioned at a distal end thereof. The rotational atherectomy device further includes an elongate penetrator extendable distal of the cutting member a predetermined maximum distance and configured to stabilize the cutting member as the cutting member engages an occlusion to control the trajectory and advancement of the cutting member through the occlusion.

Abstract: A deliver assist device for use in combination with a guide catheter includes an elongate proximal shaft and a flexible distal section that extends distally from the elongate proximal shaft. The flexible distal section includes at least a first portion having a first flexibility and a second portion having a second flexibility. A lumen configured to accommodate a guidewire extending therethrough extends through the flexible distal section. A tapered distal tip extends distally from the flexible distal section.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include an elongate tubular member having a proximal region, a distal region, and a slot formed in the tubular member between the proximal region and the distal region. The proximal region of the tubular member may be configured to shift between a first configuration and a collapsed configuration. The guide extension catheter may also include an elongate shaft for shifting the proximal region between the first configuration and the collapsed configuration.

Abstract: Guide extension catheters and methods of manufacturing and using guide extension catheters are disclosed. An example guide extension catheter may include a distal sheath having a proximal opening, a distal opening, and a central lumen extending therebetween. The guide extension catheter may also include a proximal shaft having an outer diameter smaller than an outer diameter of the distal sheath, the proximal shaft including a distal opening. The guide extension catheter may also include a coupling member for securing the distal sheath to the proximal shaft. The coupling member may include a distal portion attached to the distal sheath and a proximal portion disposed within the distal opening of the proximal shaft.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a proximal shaft having a first outer diameter. A distal sheath may be attached to the proximal shaft and may have a second outer diameter greater than the first outer diameter. A trackable tip member may be attached to the distal sheath and extending distally therefrom. The trackable tip member may define a guidewire lumen therein.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a proximal member having a proximal outer diameter. A removable stiffening member may be disposed adjacent to the proximal member. A distal sheath member may be attached to the proximal member. The distal sheath member may have a distal outer diameter greater than the proximal outer diameter.

Abstract: An intravascular filter can capture and eliminate emboli. In particular, an intravascular filter may include a plurality of filter legs extending from an apical head. The filter legs may be configured to capture emboli. A drug reservoir that includes or contains a therapeutic drug can be disposed near the apical head. The therapeutic drug, such as a thrombolytic or anti-coagulatory drug, may be eluted in response to a captured emboli.

Abstract: A catheter for stage-delivering a vena cava filter within a body lumen is disclosed. The catheter may comprise an elongated tubular member having a proximal section, a distal section, and an inner lumen configured to receive an intravascular filter. One or more notches or slits radially disposed about the distal end of the catheter may be utilized to stage-deploy the filter within the body. Several grooves or indentations disposed along an inner surface of the catheter may also be employed.

Abstract: A filter device positionable within a blood vessel for trapping emboli in the vessel, the filter device having a head and a plurality of divergent legs each secured at a first end to the head; each leg having one or more hooks at a second end. The hooks can include an expandable and contractible sleeve or hook that provides securing means for the legs and which also allows for easy removal of the filter device.

Abstract: Blood clot filters having self-centering capabilities when placed in a blood vessel are disclosed. A blood clot device in accordance with an exemplary embodiment of the present invention may include a number filter legs formed at least in part of a shape-memory material configured to transform from a centering configuration to a filtering when deployed in the body. An attachment section on the distal section of each filter leg is configured to pierce and secure the filter to the vessel wall at a first location. A bend region may be heat set into the shape-memory material to provide a second contact location along the vessel wall to aid in centering the filter within the vessel. The bend region can be formed by heating the shape-memory material above its final austenite temperature (Af), and then shaping the filter leg to form a pad that abuts the vessel wall during deployment.

Abstract: Improved methods and apparatus for capturing emboli and subsequently removing or immobilizing the captured emboli are described. Emboli can be captured within a blood vessel and can be withdrawn to a position exterior to the blood vessel. Some filters can remain within a blood vessel yet direct emboli to a position exterior to the blood vessel.