Abstract: Provided are methods of treatment comprising administering to a subject, in need thereof, a therapeutically effective amount of activated stem cells to the affected tissue or organ. The methods described herein are treatment modalities employing mesenchymal stem cells (MSC) in the treatment of mammals, as well as MSC purification and formulation methods including the “activation” or “preconditioning” of stem cells.

Abstract: Provided are methods of treatment comprising administering to a subject in need thereof a therapeutically effective amount of encapsulated cells to an affected tissue or organ.

Abstract: Methods and systems are provided for the isolation, characterization, cryopreservation and banking of human germline stem cells and gonadal tissue. Also disclosed are methods for the transplanting of the cryopreserved cells to repopulate a sterile reproductive organ.