Abstract: Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.

Abstract: Compounds of Formula (IA) and Formula (IB) are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.

Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.

Abstract: Devices having a magnet disposed thereon are disclosed. The devices are operatively configured for suspending and displaying articles, such as tags, signage, clothing, and baseball caps containing ferrous elements.

Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.

Abstract: Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.

Abstract: Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.

Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.

Abstract: Compounds of Formulae I-1 to I-9 are disclosed, which are modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders.

Abstract: Devices are disclosed having a magnet disposed thereon, operatively configured for retaining a ferrous element thereagainst.

Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.

Abstract: The present invention relates to compounds, including compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: The present invention relates to compounds, including compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: A fire safety fluid flow device for engagement with a Schrader valve including a sliding valve a housing having a fluid path therethrough and a pressing member. The pressing member presses against the sliding valve of the Schrader valve when engaged therewith to allow fluid flow through the Schrader valve. The pressing member continues to maintain the sliding valve in an open position when the device is below a predetermined temperature and connected to the Schrader valve. The pressing member is configured to no longer press against the sliding valve of the Schrader valve at and above the predetermined temperature to allow the sliding valve of the Schrader valve to thereby stop fluid flow through the Schrader valve.

Abstract: A cooking apparatus for preparing food includes a vessel, a burner, an electrically controllable valve, a thermocouple and a thermally actuated switch. The vessel is configured for containing a fluid and the burner is positioned for providing a gas flame to the vessel. The valve is coupled between the burner and a gas source and the thermocouple is positioned to sense a temperature of the flame provided by the burner. The thermally actuated switch is serially coupled between the valve and the thermocouple. The switch provides a conduction path between the valve and the thermocouple, when a temperature sensed by the thermal switch is less than a predetermined temperature. The switch is integrally mounted to the vessel to sense a temperature of the fluid contained within the vessel.