Abstract: The invention concerns compounds of general formula (I) (wherein R and R? represent an alkyl radical or an aryl group and R? is hydrogen or a CO—R1 group wherein R1 is an alkyl radical or an aryl group; and the dimers formed by the disulphide bond from one and/or the other of the two sulphur atoms of the compounds of general formula (I); and the corresponding thiazolidin forms), the methods for preparing them and uses thereof. More particularly, it concerns the use of said compounds as antioxidant agents, in particular for preparing medicines designed to increase the intracellular and/or extracellular level of glutathione (GSH).

Abstract: The invention concerns a process for preparing compounds of general formula (I) wherein R and R? represent an alkyl radical or an aryl group; and R? is hydrogen or a CO—R1 group wherein R1 is an alkyl radical or an aryl group; and wherein these compounds are or not in the thiazolidine form; by protecting the N-acyl-L-cysteine to form an intermediate compound; and then by coupling said intermediate compound with S-acylcysteamine hydrochloride or with thiazolidine.

Abstract: The invention concerns a process for preparing compounds of general formula (I) 1

Abstract: Compounds having the general formula (I), ##STR1## wherein X and Y represent individually H or --NO, at least one of them being a group-NO, n is 0, 1 or 2, R represents hydrogen, an aliphatic, cycloaliphatic, cycloaliphatic-alkyl, aryl or aralkyl radical, or a group of formula, ##STR2## wherein R.sub.1 is a lower alkyl radical or an aryl, all these radicals being optionally substituted. The present invention also relates to the compounds hereabove defined in the form of mixtures of their position isomers. Furthermore, the present invention discloses processes for preparing such compounds, as well as compositions, useful particularly in anticancerous chemotherapy, containing at least one of said compounds as an active principle.

Abstract: A pharmaceutical composition effective in the protection of normal tissues against radiation induced damage comprising administration a compound of the formulaR.sub.1 --CO--NR.sub.3 --/A/--S--R.sub.2in which R.sub.1 is a radical corresponding to an amino acid R.sub.1 --COOH, /A/ is a C.sub.2 or C.sub.3 alkylene radical which can be substituted with a C.sub.1 to C.sub.3 alkyl radical, or with a hydroxy or hydroxycarbonyl radical or a --COR radical where R is an amino or --NH--CH.sub.2 --CO.sub.2 H radical, R.sub.2 is an acyl radical which protects the thiol group and which liberates the thiol group in vivo, R.sub.3 is a hydrogen, and also the salts of this compound with pharmaceutically acceptable acids.

Abstract: The invention relates to new chemical compounds.The compounds according to the invention are compounds of the following formula ##STR1## in which one of the substituents A and B is hydrogen and the other is the radical -N.dbd.O.These compounds are suitable for use as medicaments.

Abstract: The invention relates to new chemical compounds.The compounds according to the invention are compounds of the following formula ##STR1## in which one of the substituents A and B is hydrogen and the other is the radical --N.dbd.O.These compounds are suitable for use as medicaments.