Patents by Inventor Joel R. Haynes

Joel R. Haynes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adjuvanted genetic vaccines
    Patent number: 7223739
    Abstract: Reagents useful in nucleic acid immunization techniques are described. More particularly, adjuvanted genetic vaccine compositions are described, as are methods of using those compositions for inducing an enhanced immune response against a selected antigen.
    Type: Grant
    Filed: November 3, 1999
    Date of Patent: May 29, 2007
    Assignee: Powderject Vaccines, Inc.
    Inventors: Joel R. Haynes, Georg Widera, James T. Fuller, Timothy Shipley, Deborah Fuller, Mary Wu
  • Cationic lipid-mediated enhancement of nucleic acid immunization of cats
    Patent number: 6770282
    Abstract: The present invention relates to a method to introduce a nucleic acid molecule into a felid by administration of a nucleic acid-cationic lipid complex composition. The method includes the step of administering to the felid, by a parenteral route, a nucleic acid-cationic lipid complex to elicit and/or enhance an immune response. In one embodiment, this method enhances the immune response in a felid compared to a method in which a naked DNA vaccine is administered to a felid. Also provided is a method to deliver a nucleic acid to a felid. This method comprises parenterally administering to the felid a composition that includes a nucleic acid molecule complexed with a cationic lipid.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: August 3, 2004
    Assignee: Heska Corporation
    Inventors: Joel R. Haynes, Ramani S. Wonderling, Dan T. Stinchcomb
  • Nucleic acid adjuvants
    Publication number: 20030162733
    Abstract: Recombinant nucleic acid molecules are described. The molecules have two nucleic acid sequences, wherein the first nucleic acid sequence is a truncated A subunit coding region obtained or derived from a bacterial ADP-ribosylating exotoxin, and the second nucleic acid sequence is a truncated B subunit coding region. Vectors and compositions containing these molecules are also described. Methods for enhancing an immune response against an antigen of interest using these recombinant nucleic acid molecules and compositions are also described.
    Type: Application
    Filed: November 26, 2001
    Publication date: August 28, 2003
    Inventors: Joel R. Haynes, Joshua Arrington
  • Nucleic acid immunization
    Publication number: 20020165176
    Abstract: Recombinant nucleic acid molecules are described. The molecules have a sequence or sequences encoding an influenza virus M2 antigen. Vectors and compositions containing these molecules are also described. Methods for eliciting an immune response using these molecules and compositions are also described.
    Type: Application
    Filed: April 30, 2001
    Publication date: November 7, 2002
    Inventors: Joel R. Haynes, Michael D. Macklin, Lendon G. Payne
  • Genetic induction of anti-viral immune response and genetic vaccine for filovirus
    Patent number: 6200959
    Abstract: An approach to genetic vaccine methodology is described. A genetic construction encoding antigenic determinants of a filovirus is transfected into cells of the vaccinated individuals using a particle acceleration protocol so as to express the viral antigens in healthy cells to produce an immune response to those antigens.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: March 13, 2001
    Assignee: PowerJect Vaccines Inc.
    Inventors: Joel R. Haynes, Connie S. Schmaljohn, Deborah L. Fuller, Alan Schmaljohn, Peter B. Jahrling