Abstract: A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively wetting a membrane within the device, making the membrane permeable and allowing transport of a drug across the membrane and into the passageway wall or body tissue.

Abstract: A microporous polyetheretherketone (PEEK) membrane in the form of films and hollow fibers formed without sulfonating the PEEK polymer. Solid fibers and articles are also claimed. A method of making membranes, fibers and articles from solutions of PEEK in non-sulfonating acid solvents in claimed. Solvents include methane sulfonic acid and trifluoromethane sulfonic acid. Sulfuric acid may be used as a diluent in non-sulfonating amounts. PEEK membranes are used as supports for composite ultrafiltration and reverse osmosis membranes. A method of making membranes, fibers, and articles is also described.

Abstract: A reverse osmosis membrane having improved rejection of sulfuric acid and/or isopropanol is described. The membrane is prepared by treating a crosslinked, polyamide discriminating layer with a compatible oxidizing reagent, such as peracetic acid, periodic acid or chloramine, whereby the passage through the treated membrane of sulfuric acid in a 2 percent aqueous solution at a transmembrane pressure of 400 psi is reduced by at least 30 percent.