Patents by Inventor Joelle Le

Joelle Le has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Compounds
    Publication number: 20110183973
    Abstract: The invention is directed to certain novel compounds directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
    Type: Application
    Filed: June 3, 2009
    Publication date: July 28, 2011
    Inventors: Ian Robert Baldwin, Kenneth David Down, Paul Faulder, Simon Gaines, Julie Nicole Hamblin, Paul Spencer Jones, Joelle Le, Nigel James Parr, Timothy John Ritchie, John Edward Robinson, Juliet Kay Simpson, Christian Alan Paul Smethurst
  • BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES
    Publication number: 20110178063
    Abstract: The invention is directed to certain novel compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
    Type: Application
    Filed: June 3, 2009
    Publication date: July 21, 2011
    Applicant: GLAXO GROUP LIMITED
    Inventors: Ian Robert Baldwin, Kenneth David Down, Paul Faulder, Simon Gaines, Julie Nicole Hamblin, Joelle Le, Christopher James Lunniss, Nigel James Parr, Timothy John Ritchie, John Edward Robinson, Juliet Kay Simpson, Christian Alan Paul Smethurst
  • Novel Compounds
    Publication number: 20110118246
    Abstract: The invention is directed to to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
    Type: Application
    Filed: June 3, 2009
    Publication date: May 19, 2011
    Inventors: Ian Robert Baldwin, Kenneth David Down, Paul Faulder, Simon Gaines, Julie Nicole Hamblin, Joelle Le, Christopher James Lunniss, Nigel James Parr, Timothy John Ritchie, Juliet Kay Simpson, Christian Alan Paul Smethurst
  • 4-CARBOXAMIDE INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF P13-KINASES
    Publication number: 20110112070
    Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of P13-kinase activity.
    Type: Application
    Filed: June 3, 2009
    Publication date: May 12, 2011
    Inventors: Ian Robert Baldwin, Kenneth David Down, Paul Faulder, Simon Gaines, Julie Nicole Hamblin, Katherine Louise Jones, Joelle Le, Christopher James Lunniss, Nigel James Parr, Timothy John Ritchie, Christian Alan Paul Smethurst, Yoshiaki Washio
  • NOVEL COMPOUNDS
    Publication number: 20100280029
    Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.
    Type: Application
    Filed: April 28, 2010
    Publication date: November 4, 2010
    Inventors: Julie Nicole HAMBLIN, Paul Spencer Jones, Suzanne Elaine Keeling, Joelle Le, Charlotte Jane Mitchell, Nigel James Parr
  • NOVEL COMPOUNDS
    Publication number: 20100280045
    Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular Pl3-kinase activity.
    Type: Application
    Filed: April 28, 2010
    Publication date: November 4, 2010
    Inventors: Julie Nicole HAMBLIN, Paul Spencer Jones, Suzanne Elaine Keeling, Joelle Le, Nigel James Parr
  • Pyrazolo[1,5-a]pyrimidine derivatives
    Patent number: 7667036
    Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent MAPKAP-K2 inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for MAPKAP-K2 mediated disorder, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
    Type: Grant
    Filed: August 12, 2005
    Date of Patent: February 23, 2010
    Assignee: Teijin Pharma Limited
    Inventors: Tomomi Kosugi, Minoru Imai, Hiroaki Makino, Mika Takakuwa, Gen Unoki, Kenichiro Kataoka, Dale Robert Mitchell, Donald James Simpson, Clifford John Harris, Joelle Le, Yuko Yamakoshi
  • Pyrazolo[1,5-A] pyrimidine derivatives
    Patent number: 7557110
    Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent kinase inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for a protein kinase mediated disorder in which kinase is implicated, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
    Type: Grant
    Filed: March 1, 2004
    Date of Patent: July 7, 2009
    Assignee: Teijin Pharma Limited
    Inventors: Kenichiro Kataoka, Naotaka Suzuki, Tomomi Kosugi, Minoru Imai, Hiroaki Makino, Mika Takakuwa, Gen Unoki, Aiko Fujino, Yasuhiro Oue, Yuko Yamakoshi, Satoshi Sugiura, Robert Dale Mitchell, James Donald Simpson, John Clifford Harris, Joelle Le
  • Antiviral 2-Carboxy-Thiophene Compounds
    Publication number: 20090136448
    Abstract: Anti-viral agents of compounds of Formula (I): wherein A, R1, R2 and R3 are as defined in the specification, processes for their preparation and their use in HCV treatment are provided.
    Type: Application
    Filed: December 20, 2006
    Publication date: May 28, 2009
    Inventors: John Andrew Corfield, Richard Martin Grimes, David Harrison, Charles David Hartley, Peter David Howes, Joelle Le, Malcolm Lees Meeson, Jacqueline Elizabeth Mordaunt, Pritom Shah, Martin John Slater, Gemma Victoria White
  • Pharmaceutically active 4,6-disubstituted aminopyrimidine derivatives as modulators of protein kinases
    Publication number: 20070191344
    Abstract: The present invention relates to 4,6-disubstituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, and pharmaceutical compositions containing at least one of said 4,6-di substituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: September 15, 2004
    Publication date: August 16, 2007
    Inventors: Axel Choidas, Alexander Backes, Matt Cotten, Ola Engkvist, Beatrice Felber, Achim Freisleben, Klaus Godl, Zoltan Greff, Peter Habenberger, Doris Hafenbradl, Christian Hartung, Thomas Herget, Edmund Hoppe, Bert Klebl, Andrea Missio, Gerhard Muller, Wilfried Schwab, Birgit Zech, Jose Bravo, John Harris, Joelle Le, Jackie Macritchie, Vladimir Savic, Brad Sherborne, Don Simpson
  • Pyrazolo[1,5-A] pyrimidine derivatives
    Publication number: 20060189632
    Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent kinase inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for a protein kinase mediated disorder in which kinase is implicated, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
    Type: Application
    Filed: March 1, 2004
    Publication date: August 24, 2006
    Inventors: Kenichiro Kataoka, Naotaka Suzuki, Tomomi Kosugi, Minoru Imai, Hiroaki Makino, Mika Takakuwa, Gen Unoki, Aiko Fujino, Yasuhiro Oue, Yuko Yamakoshi, Satoshi Sugiura, Robert Mitchell, James Simpson, John Harris, Joelle Le
  • Pyrazolo[1,5-a]pyrimidine derivatives
    Publication number: 20060135514
    Abstract: The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent MAPKAP-K2 inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for MAPKAP-K2 mediated disorder, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
    Type: Application
    Filed: August 12, 2005
    Publication date: June 22, 2006
    Inventors: Tomomi Kosugi, Minoru Imai, Hiroaki Makino, Mika Takakuwa, Gen Unoki, Kenichiro Kataoka, Dale Mitchell, Donald Simpson, Clifford Harris, Joelle Le, Yuko Yamakoshi