Patents by Inventor Joerg Berghausen

Joerg Berghausen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Salt of dimethylaminomethyl-phenyl-cyclohexane and crystalline forms thereof
    Patent number: 7884247
    Abstract: Novel 3-[2-(dimethylamino)methyl-(cyclohex-1-yl)]-phenol maleate compounds corresponding to formula I and processes for preparing these compounds are provided. Pharmaceutical compositions including these compounds and methods of treating or alleviating pain with these compounds are also provided.
    Type: Grant
    Filed: July 24, 2006
    Date of Patent: February 8, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Michael Gruss, Wolfgang Hell, Martin Szelagiewicz, Joerg Berghausen, Susan Margaret De Paul, Markus Von Raumer
  • Salts of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-y1)-N?-(4-(2-methylpropyloxy)phenylmethyl)carbamide and their preparation
    Patent number: 7868176
    Abstract: Disclosed herein are salts of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy) phenylmethyl)carbamide including the citrate, fumarate, maleate, malate, phosphate, succinate, sulphate, and edisylate salts.
    Type: Grant
    Filed: September 26, 2005
    Date of Patent: January 11, 2011
    Assignee: ACADIA Pharmaceuticals, Inc.
    Inventors: Mikkel Boas Thygesen, Nathalie Schlienger, Bo-Ragnar Tolf, Fritz Blatter, Jörg Berghausen
  • Crystalline forms of Rizatriptan benzoate
    Patent number: 7777049
    Abstract: The present invention is directed to the novel polymorphic Form A and Form B of Rizatriptan benzoate, processes for the preparation thereof and pharmaceutical compositions comprising these crystalline forms.
    Type: Grant
    Filed: January 5, 2005
    Date of Patent: August 17, 2010
    Assignee: ratiopharm GmbH
    Inventors: Paul Adriaan Van Der Schaaf, Jörg Berghausen, Fritz Blatter, Martin Szelagiewicz, Ulrich Berens
  • N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
    Patent number: 7732615
    Abstract: Disclosed herein are methods for synthesizing N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)-phenylmethyl)carbamide. Also disclosed herein is the hemi-tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2 -methylpropyloxy)-phenylmethyl)carbamide and methods for obtaining the salt. Further disclosed are various crystalline forms of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)-phenylmethyl)carbamide and its hemi-tartrate salt including various polymorphs and solvates.
    Type: Grant
    Filed: September 26, 2005
    Date of Patent: June 8, 2010
    Assignee: ACADIA Pharmaceuticals Inc.
    Inventors: Mikkel Boas Thygesen, Nathalie Schlienger, Bo-Ragnar Tolf, Carl-Magnus A. Andersson, Fritz Blatter, Jörg Berghausen
  • HCl Polymorphs of 3-((2-(Dimethylamino)methyl-(cyclohex-1-yl))phenol
    Publication number: 20100076085
    Abstract: A crystalline salt of 3-[2-(dimethylamino)methyl(cyclohex-1-yl)]phenol and hydrogen chloride, preferably in a 1:1 composition, including various crystalline forms of this salt, processes for preparing the various crystalline forms of this salt, pharmaceutical compositions containing the various crystalline forms of this salt, and the use of this salt as a pharmacologically active agent in a pharmaceutical composition to treat or inhibit pain or other disorders or disease states.
    Type: Application
    Filed: November 30, 2009
    Publication date: March 25, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Michael Gruss, Andreas Fischer, Markus Kegel, Wolfgang Hell, Markus Von Raumer, Joerg Berghausen, Susan Margaret Paul
  • Cephalosporin in Crystalline Form
    Publication number: 20090192306
    Abstract: The present invention relates to cephalosporin of formula (I) in crystalline form. The compound of formula (I) in crystalline form is useful as antibiotics having potent and broad antibacterial activity; especially against methicillin resistant Staphylococci (MRSA) and Pseudomonas aeruginosa.
    Type: Application
    Filed: April 1, 2009
    Publication date: July 30, 2009
    Inventor: Joerg Berghausen
  • Cephalosporin salts in crystalline form
    Patent number: 7531650
    Abstract: The present invention relates to cephalosporin of formula (I) in crystalline form. The compound of formula (I) in crystalline form is useful as antibiotics having potent and broad antibacterial activity; especially against methicillin resistant Staphylococci (MRSA) and Pseudomonas aeruginosa.
    Type: Grant
    Filed: March 15, 2004
    Date of Patent: May 12, 2009
    Assignee: Basilea Pharmaceutica AG
    Inventor: Joerg Berghausen
  • HCI POLYMORPHS OF 3-((2-(DIMETHYLAMINO)METHYL(CYCLOHEX-1-YL)) PHENOL
    Publication number: 20080255242
    Abstract: A crystalline salt of 3-[2-(dimethylamino)methyl(cyclohex-1-yl)] phenol and hydrogen chloride, preferably in a 1:1 composition, including various crystalline forms of this salt, processes for preparing the various crystalline forms of this salt, pharmaceutical compositions containing the various crystalline forms of this salt, and the use of this salt as a pharmacologically active agent in a pharmaceutical composition to treat or inhibit pain or other disorders or disease states.
    Type: Application
    Filed: January 18, 2008
    Publication date: October 16, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Michael Gruss, Andreas Fischer, Markus Kegel, Wolfgang Hell, Markus Von Raumer, Joerg Berghausen, Susan Margaret Paul
  • Salt of dimethylaminomethyl-phenyl-cyclohexane and crystalline forms thereof
    Publication number: 20070032551
    Abstract: Novel 3-[2-(dimethylamino)methyl-(cyclohex-1-yl)]-phenol fumarate compounds corresponding to formula I: and processes for preparing these compounds are provided. Pharmaceutical compositions including these compounds and methods of treating or alleviating pain with these compounds are also provided.
    Type: Application
    Filed: July 24, 2006
    Publication date: February 8, 2007
    Applicant: GRUENENTHAL GMBH
    Inventors: Michael Gruss, Wolfgang Hell, Joerg Berghausen, Martin Szelagiewicz, Markus Von Raumer, Susan De Paul
  • Salt of dimethylaminomethyl-phenyl-cyclohexane and crystalline forms thereof
    Publication number: 20070032552
    Abstract: Novel 3-[2-(dimethylamino)methyl-(cyclohex-1-yl)]-phenol maleate compounds corresponding to formula I and processes for preparing these compounds are provided. Pharmaceutical compositions including these compounds and methods of treating or alleviating pain with these compounds are also provided.
    Type: Application
    Filed: July 24, 2006
    Publication date: February 8, 2007
    Applicant: GRUENENTHAL GMBH
    Inventors: Michael Gruss, Wolfgang Hell, Martin Szelagiewicz, Joerg Berghausen, Susan De Paul, Markus Von Raumer
  • Cephalosporin in crystalline form
    Publication number: 20060167242
    Abstract: The present invention relates to cephalosporin of formula (I) in crystalline form.
    Type: Application
    Filed: March 15, 2004
    Publication date: July 27, 2006
    Inventor: Joerg Berghausen
  • Method of synthesis and isolation of solid N-desmethylclozapine and crystalline forms thereof
    Publication number: 20050282800
    Abstract: Disclosed herein are crystalline Forms A, B, C, D, and E of N-desmethylclozapine, methods of preparing the same, pharmaceutical compositions comprising the same, and methods of therapeutic treatment involving N-desmethylclozapine polymorphic forms.
    Type: Application
    Filed: March 31, 2005
    Publication date: December 22, 2005
    Inventors: Bo-Ragnar Tolf, Mikkel Thygesen, Fritz Blatter, Jörg Berghausen