Abstract: In Positron Emission Tomography, a time window (260) and an energy window (225) are dynamically adjusted, based on an attenuation map, count rate, clinical application, discrimination tailoring, and/or offline discrimination tailoring. Detected radiation events are filtered using the dynamically adjusted energy and time windows into scattered events, random events, and true events. The true events are input to image reconstruction, correction, and error analysis.

Abstract: A system and method are provided to automatically assess a confidence in imaging data based on a proposed diagnostic task or treatment decision, by determining one or more imaging quality indicators relating to the imaging data corresponding to a confidence of the proposed diagnostic task or treatment decision, comparing those imaging quality indicators with confidence benchmark values, and determining a confidence value indicative of the confidence in the imaging data for purposes of performing the proposed diagnostic task or making the proposed treatment decision.

Abstract: The subject disclosure presents systems and methods for separating colors in an image by automatically and adaptively adjusting reference vectors based on information specific to the assay being imaged, resulting in an optimized unmixing process that provides stain information that is physically and physiologically plausible. The reference vectors are optimized iteratively, based on minimizing non-negative color contributions, background contributions, high-frequencies in color channels specific to background or unwanted fluorescence, signals from known immunohistochemical markers, and pairs of stains known to carry physiologically independent information. Adjustments to the reference vectors may be allowed within a range that is predetermined based on measuring colors from multiple input images.

Abstract: A method comprises: acquiring imaging data using a tomographic radiological imaging apparatus (10); updating a calibration (42, 52) based on current information about the imaging apparatus; calibrating the imaging data using the up-to-date calibration; and reconstructing the calibrated imaging data to generate an image. The updating may be based on a current state of an idle or parked imaging modality that is not used in acquiring the imaging data, or on a measurement acquired together with the imaging data, or on the imaging data itself. For cone-beam computed tomography (CBCT) imaging data, the updating may comprise determining an intensity scale based upon intensity of at least one air pixel measured during the acquiring of the CBCT imaging data and updating an air scan template (60) by the intensity scale.

Abstract: When correcting for artifacts on an attenuation map caused by an artifact source in a computed tomography image, nuclear images are reconstructed two or more times, each time using a different correction technique or uncorrected attenuation data. Corresponding voxels in the reconstructed images are compared to identify local areas that change, i.e., are fragile and therefore low-confidence, and areas that do not vary or exhibit little variance among the plurality of reconstructed images and are thus accorded a higher confidence. The reconstructed nuclear image is overlaid with color encoding indicative of the amount of confidence accorded to each voxel value obtained by attenuation-corrected tomographic reconstruction.

Abstract: A method includes obtaining both first inflow and first perfusion metrics for non-healthy tissue of interest, obtaining both second inflow and second perfusion metrics for healthy tissue of interest, and concurrently presenting both the first flow and perfusion metrics for the non-healthy tissue of interest and both the second flow and perfusion metrics for the healthy tissue of interest.

Abstract: An x-ray computed tomography system (14) includes a gantry (15), a plurality of elements (18), and one or more processors (28). The gantry (15) moves to different orientations and generates x-ray data which includes image projection data at a plurality of the orientations. The plurality of elements (18) connect to the gantry and cause x-ray attenuation of the generated projection data. The one or more processors (28) are programmed to receive (60) the generated x-ray data and decompose (62) the received image projection data into indications of relative positions of the plurality of elements at different orientations of the gantry.

Abstract: Despite intense research activities in the field of computer-aided diagnosis methods of computer vision, automated classification or comparable algorithmic solutions are not regularly used and even less regularly trusted by physicians. According to an exemplary embodiment of the present invention, a confidence interval of the performed diagnosis is visualized and a standardized feedback mechanism is provided which allows for an interactive improvement of the method.

Abstract: A medical imaging system includes a data store (16) of re-construction procedures, a selector (24), a reconstructor (14), a fuser (28), and a display (22). The data store (16) of reconstruction procedures identifies a plurality of reconstruction procedures. The selector (24) selects at least two reconstruction procedures from the data store of reconstruction procedures based on a received input, each reconstruction procedure optimized for one or more image characteristics. The reconstructor (14) concurrently performs the selected at least two reconstruction procedures, each reconstruction procedure generates at least one image (26) from the at least one data store of imaging data (12). The fuser (28) fuses the at least two generated medical images to create a medical diagnostic image which includes characteristics from each generated image (26). The display (22) displays the medical diagnostic image.

Abstract: A system includes a perfusion information determiner (124) that determines perfusion information based on a combination of pre-perfusion scan image data and perfusion scan image data.

Abstract: In Positron Emission Tomography, a time window (260) and an energy window (225) are dynamically adjusted, based on an attenuation map, count rate, clinical application, discrimination tailoring, and/or offline discrimination tailoring. Detected radiation events are filtered using the dynamically adjusted energy and time windows into scattered events, random events, and true events. The true events are input to image reconstruction, correction, and error analysis.

Abstract: A hybrid imaging system including a first imaging system configured to acquire low resolution anatomical data of a first field of view of an anatomical structure. A second imaging system is configured to acquire functional data of the first field of view of the anatomical structure. A reconstruction processor is configured to reconstruct the functional data based on attenuation data into an attenuation corrected image. In response to the attenuation corrected image showing regions of interest, with the first imaging system or another imaging system acquiring high resolution data of one or more portions of the first field of view containing the regions of interest. The reconstruction processor reconstructs the high resolution anatomical data into one or more high resolution images of the regions of interest.

Abstract: A nuclear imaging apparatus (8) acquires nuclear imaging data comprising events wherein each event records at least spatial localization information and a timestamp for a nuclear decay event. An event-preserving image reconstruction module (22) reconstructs the nuclear imaging data using an event-preserving reconstruction algorithm to generate an image represented as an event-preserving reconstructed image dataset (ID) comprising for each event the timestamp and at least one spatial voxel assignment. One or more structures are identified in the image and independent motion compensation is performed for each structure. In one approach, an events group is identified corresponding to the structure comprising events assigned to the structure by the event-preserving reconstructed image dataset; a time binning of the events of each events group is optimized based on a motion profile for the structure; time bin images are generated; and the structure is spatially registered in the time bin images.

Abstract: A method includes determining, via a processor, functional information about tissue of interest in image data for a functional image acquisition based on reference information generated based on non-tissue of interest.

Abstract: A method comprises: acquiring imaging data using a tomographic radiological imaging apparatus (10); updating a calibration (42, 52) based on current information about the imaging apparatus; calibrating the imaging data using the up-to-date calibration; and reconstructing the calibrated imaging data to generate an image. The updating may be based on a current state of an idle or parked imaging modality that is not used in acquiring the imaging data, or on a measurement acquired together with the imaging data, or on the imaging data itself. For cone-beam computed tomography (CBCT) imaging data, the updating may comprise determining an intensity scale based upon intensity of at least one air pixel measured during the acquiring of the CBCT imaging data and updating an air scan template (60) by the intensity scale.

Abstract: The invention relates to a rotational X-ray device (100), for example a CT scanner, for generating phase contrast images of an object (1). In a particular embodiment of the device (100), a plurality of X-ray sources (11), an X-ray detector (30), and an analyzer grating (G2) are attached to a rotatable gantry (20), while a ring-shaped phase grating (G1) is stationary. The X-ray sources are disposed such that X-rays first pass an object under study before traversing the phase grating (G1) and subsequently the analyzer grating (G2). This is achieved by either shifting the X-ray sources axially with respect to the ring-shaped phase grating (G1) or by disposing the X-ray sources in the interior of the ring. Moreover, the phase grating (G1) and the analyzer (G2) shall have spatially varying relative phase (and/or periodicity), for example realized by line grids that are tilted with respect to each other.

Abstract: Scattered radiation has non-intuitive properties. A signalling system (28) is presented which provides a perceptible signal (34) being indicative of a predicted or measured spatial distribution of scattered radiation. An embodiment provides for easy assessment of the individual risk of scattered radiation exposure for personnel working in an environment exposed to scattered radiation. A method for predicting a distribution of scattered radiation takes into account at least one object related parameter (18) and at least one radiation related parameter (22) and, in response hereto, predicts a distribution of scattered radiation.

Abstract: When correcting for artifacts on an attenuation map caused by an artifact source in a computed tomography image, nuclear images are reconstructed two or more times, each time using a different correction technique or uncorrected attenuation data. Corresponding voxels in the reconstructed images are compared to identify local areas that change, i.e., are fragile and therefore low-confidence, and areas that do not vary or exhibit little variance among the plurality of reconstructed images and are thus accorded a higher confidence. The reconstructed nuclear image is overlaid with color encoding indicative of the amount of confidence accorded to each voxel value obtained by attenuation-corrected tomographic reconstruction.

Abstract: A method includes displaying at least one of projection data or reconstructed image data having visually observable artifacts, wherein the at least one of the projection data or the reconstructed image data corresponds to an imaging examination of an object or subject and displaying, concurrently with the at least one of the projection data or the reconstructed image data, sample images with known artifacts. The method further includes identifying one or more of the sample images having artifacts similar to the visually observable artifacts in the at least one of the projection data or the reconstructed image data. The method further includes displaying information about the identified one or more of the sample images, wherein the information includes information related to mitigating the visually observable artifacts.

Abstract: A method for acquiring X-ray image data of an imaging volume is disclosed, the method using a detector and a distributed X-ray source structure having a plurality of single source elements, which are uniformly distributed with a common pitch to each other, the method comprises moving the distributed X-ray source structure and/or the detector with respect to the imaging volume, importantly, the maximum moving distance dmax of the distributed X-ray source structure during the acquisition of the X-ray image data is limited to the length lp of the pitch. Emitting of X-rays from the distributed X-ray source structure and generating a plurality of signals in response to the X-rays incident upon the detector are executed during the movement.