Patents by Inventor Joerg Bussenirs

Joerg Bussenirs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • [1H-Pyrazolo[3, 4-D]Pyrimidin-4-Yl]-Piperidine or -Piperazine Compounds as Serine-Theoronine Kinase Modulators (P70s6k, Atk1 and Atk2) for the Treatment of Immunological, Inflammatory and Proliferative Diseases
    Publication number: 20080188482
    Abstract: The invention provides compounds of formula (I) and methods for inhibition of kinases, more specifically p70S6 kinases, and more preferably p70S6, Akt-1 and Akt-2 kinases. The invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration, chemoinvasion and metabolism. Compounds of the invention inhibit, regulate and/or modulate kinase receptor signal transduction pathways related to the changes in cellular activities as mentioned above, and the invention includes compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions.
    Type: Application
    Filed: December 27, 2005
    Publication date: August 7, 2008
    Applicant: EXELIXIS, INC.
    Inventors: Ken Rice, Erick Wang Co, Moon Hwan Kim, Lynne Canne Bannen, Joerg Bussenirs, Donna Tra Le, Amy Lew Tsuhako, John Nuss, Yong Wang, Wei Xu, Rhett Ronald Klein