Patents by Inventor Joerg Czech

Joerg Czech has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
    Patent number: 6475486
    Abstract: The present invention relates to glycosyl-etoposide prodrugs, a process for the preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates for treating cancers.
    Type: Grant
    Filed: June 30, 1999
    Date of Patent: November 5, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Cenek Kolar, Jörg Czech, Klaus Bosslet, Gerhard Seemann, Hans-Harald Sedlacek, Dieter Hoffman
  • Cytoplasmic expression of antibodies, antibody fragments and antibody fragment fusion proteins in E. coli
    Patent number: 6008023
    Abstract: The invention relates to the cytoplasmic expression of antibodies, antibody fragments and antibody fragment fusion molecules in E. coli. In particular, antibody fragment fusion molecules having an antibody moiety which is directed against tumors and an enzyme moiety which cleaves a nontoxic prodrug to give the toxic drug can be advantageously prepared in this way while retaining their respective functional properties.
    Type: Grant
    Filed: April 10, 1996
    Date of Patent: December 28, 1999
    Assignee: Hoechst Marion Roussel Deutschland GmbH
    Inventors: Martin Opper, Klaus Bosslet, Joerg Czech