Patents by Inventor Joerg Friedrich

Joerg Friedrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240302376
    Abstract: The invention generally relates to the field of individualized medicine. It is a kind of liquid biopsy for individualizing and monitoring treatment in patients with tumors and for diagnosis of tumors. The invention relates to a method for identifying and characterizing subpopulations (subgroups) of circulating tumor cells (CTCs) in a population of CTCs in a biological sample, preferably in a blood sample of the patient. The invention also relates to the quantification of the respective subgroups of CTCs in the population of CTCs in the biological sample. The invention further relates to the use of the method for diagnosis and monitoring of tumors, decisions relating to treatment, surveillance of treatment and prognosis, in particular for all kinds of solid tumors. The invention further relates to the use of the identified CTC subgroups as biomarkers for diagnosis, prognosis and therapeutic treatment.
    Type: Application
    Filed: July 5, 2023
    Publication date: September 12, 2024
    Inventors: Andreas-Claudius HOFFMANN, Joerg Friedrich SCHLAAK
  • Publication number: 20210389328
    Abstract: The invention generally relates to the field of individualized medicine. It is a kind of liquid biopsy for individualizing and monitoring treatment in patients with tumors and for diagnosis of tumors. The invention relates to a method for identifying and characterizing subpopulations (subgroups) of circulating tumor cells (CTCs) in a population of CTCs in a biological sample, preferably in a blood sample of the patient. The invention also relates to the quantification of the respective subgroups of CTCs in the population of CTCs in the biological sample. The invention further relates to the use of the method for diagnosis and monitoring of tumors, decisions relating to treatment, surveillance of treatment and prognosis, in particular for all kinds of solid tumors. The invention further relates to the use of the identified CTC subgroups as biomarkers for diagnosis, prognosis and therapeutic treatment.
    Type: Application
    Filed: January 11, 2021
    Publication date: December 16, 2021
    Inventors: Andreas-Claudius Hoffmann, Joerg Friedrich Schlaak
  • Patent number: 10960846
    Abstract: An inflator as well as a method of manufacturing an inflator, a module including an inflator and an airbag module. In an inflator, especially for a protective device in a vehicle, comprising plural components a sealant is applied in the area of abutting components, especially a sealant which adheres to both abutting components.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: March 30, 2021
    Assignee: ZF AIRBAG GERMANY GMBH
    Inventors: Sebastian Bierwirth, Achim Hofmann, Hans-Peter Neumayer, Dieter Spitzenberger, Franz Fuerstenberger, Hannes Nuiding, Dieter Leier, Georg Schoenhuber, Joerg Friedrich
  • Publication number: 20200238945
    Abstract: An inflator as well as a method of manufacturing an inflator, a module including an inflator and an airbag module. In an inflator, especially for a protective device in a vehicle, comprising plural components a sealant is applied in the area of abutting components, especially a sealant which adheres to both abutting components.
    Type: Application
    Filed: February 21, 2020
    Publication date: July 30, 2020
    Inventors: Sebastian Bierwirth, Achim Hofmann, Hans-Peter Neumayer, Dieter Spitzenberger, Franz Fuerstenberger, Hannes Nuiding, Dieter Leier, Georg Schoenhuber, Joerg Friedrich
  • Patent number: 10589709
    Abstract: An inflator as well as a method of manufacturing an inflator, a module including an inflator and an airbag module. In an inflator, especially for a protective device in a vehicle, comprising plural components a sealant is applied in the area of abutting components, especially a sealant which adheres to both abutting components.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: March 17, 2020
    Assignee: TRW AIRBAG SYSTEMS GMBH
    Inventors: Sebastian Bierwirth, Achim Hofmann, Hans-Peter Neumayer, Dieter Spitzenberger, Franz Fuerstenberger, Hannes Nuiding, Dieter Leier, Georg Schoenhuber, Joerg Friedrich
  • Patent number: 10160862
    Abstract: The invention relates to a process for producing a titanium dioxide pigment obtainable by the sulfate process with a narrow particle size distribution, the pigment itself, and the use of said pigments in coatings and printing inks.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: December 25, 2018
    Assignee: Kronos International, Inc.
    Inventors: Volker Juergens, Siegfried Bluemel, Achim Abdin, Joerg Friedrich, Volker Schmitt
  • Patent number: 9909011
    Abstract: A method for coating the surface of inorganic solid particles in an aqueous suspension, particularly for coating titanium dioxide with SiO2 includes: a) disagglomeration of the solid particles contained in aqueous suspension, b) addition of a water-soluble precursor of the coating substance to the suspension, c) immediately following step b) homogenization of the suspension, where the temperature and pH value of the suspension do not change significantly in steps a) to c), d) feeding the slurry into a tank and precipitation of the coating substance onto the particle surface and, optionally, application of further coatings, and e) separation of the solid particles from the suspension. The method produces to a highly homogeneous and continuous skin on the particle surface, and to less separately precipitated coating substance.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: March 6, 2018
    Assignee: Kronos International, Inc.
    Inventors: Heiko Frahm, Joerg Friedrich, Mark Kaminski, Erwin Schmeier, Lydia Drews-Nicolai, Volker Juergens
  • Publication number: 20170341617
    Abstract: An inflator as well as a method of manufacturing an inflator, a module including an inflator and an airbag module. In an inflator, especially for a protective device in a vehicle, comprising plural components a sealant is applied in the area of abutting components, especially a sealant which adheres to both abutting components.
    Type: Application
    Filed: August 15, 2017
    Publication date: November 30, 2017
    Inventors: Sebastian Bierwirth, Achim Hofmann, Hans-Peter Neumayer, Dieter Spitzenberger, Franz Fuerstenberger, Hannes Nuiding, Dieter Leier, Georg Schoenhuber, Joerg Friedrich
  • Publication number: 20170210906
    Abstract: The invention relates to a process for producing a titanium dioxide pigment obtainable by the sulfate process with a narrow particle size distribution, the pigment itself, and the use of said pigments in coatings and printing inks.
    Type: Application
    Filed: January 20, 2017
    Publication date: July 27, 2017
    Inventors: Volker Juergens, Siegfried Bluemel, Achim Abdin, Joerg Friedrich, Volker Schmitt
  • Patent number: 9539560
    Abstract: A method for manufacturing a photocatalyst, based on titanium dioxide containing carbon or metal, in a pulsation reactor, where a raw material mixture, consisting of nanoparticulate titanium oxyhydrate and an aqueous solution or suspension, containing at least one organic, carbon-containing compound or metal ions, is fed into the pulsating hot-gas stream of the pulsation reactor and the titanium dioxide particles containing carbon or metal are formed. The hot-gas stream has a temperature of ?450° C. following addition of the material and contains an excess of oxygen. In contrast to the known manufacturing methods, the method according to the invention allows reproducibly good product qualities to be achieved.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: January 10, 2017
    Assignee: Kronos International, Inc.
    Inventors: Joerg Friedrich, Raimund Meifert
  • Publication number: 20160038916
    Abstract: A method for manufacturing a photocatalyst, based on titanium dioxide containing carbon or metal, in a pulsation reactor, where a raw material mixture, consisting of nanoparticulate titanium oxyhydrate and an aqueous solution or suspension, containing at least one organic, carbon-containing compound or metal ions, is fed into the pulsating hot-gas stream of the pulsation reactor and the titanium dioxide particles containing carbon or metal are formed. The hot-gas stream has a temperature of ?450° C. following addition of the material and contains an excess of oxygen. In contrast to the known manufacturing methods, the method according to the invention allows reproducibly good product qualities to be achieved.
    Type: Application
    Filed: August 6, 2015
    Publication date: February 11, 2016
    Inventors: Joerg Friedrich, Raimund Meifert
  • Publication number: 20160016529
    Abstract: An inflator as well as a method of manufacturing an inflator, a module including an inflator and an airbag module. In an inflator, especially for a protective device. In a vehicle, comprising plural components a sealant is applied in the area of abutting components, especially a sealant which adheres to both abutting components.
    Type: Application
    Filed: August 25, 2015
    Publication date: January 21, 2016
    Inventors: Sebastian Bierwirth, Achim Hofmann, Hans-Peter Neumayer, Dieter Spitzenberger, Franz Fuerstenberger, Hannes Nuiding, Dieter Leier, Georg Schoenhuber, Joerg Friedrich
  • Patent number: 9139156
    Abstract: An inflator as well as a method of manufacturing an inflator, a module including an inflator and an airbag module. In an inflator, especially for a protective device in a vehicle, comprising plural components a sealant is applied in the area of abutting components, especially a sealant which adheres to both abutting components.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: September 22, 2015
    Assignee: TRW AIRBAG SYSTEMS GMBH
    Inventors: Sebastian Bierwirth, Achim Hofmann, Hans-Peter Neumayer, Dieter Spitzenberger, Franz Fuerstenberger, Hannes Nuiding, Dieter Leier, Georg Schoenhuber, Joerg Friedrich
  • Publication number: 20150147761
    Abstract: The invention relates to specific marker proteins (biomarkers) for Hepatocellular carcinoma (HCC). The invention relates to a method for the diagnostic study of biological samples of a human for Hepatocellular carcinoma, the sample being studied for one or more proteins as a marker for Hepatocellular carcinoma, a concentration of the proteins which is elevated or decreased in relation to the healthy state indicating the presence of Hepatocellular carcinoma, a diagnostic test kit and a method of screening compounds effective in HCC.
    Type: Application
    Filed: June 20, 2013
    Publication date: May 28, 2015
    Inventors: Helmut E. Meyer, Barbara Sitek, Dominik A. Megger, Thilo Bracht, Hideo Andreas Baba, Joerg Friedrich Schlaak, Frank Weber
  • Publication number: 20110101651
    Abstract: An inflator as well as a method of manufacturing an inflator, a module including an inflator and an airbag module. In an inflator, especially for a protective device in a vehicle, comprising plural components a sealant is applied in the area of abutting components, especially a sealant which adheres to both abutting components.
    Type: Application
    Filed: September 29, 2009
    Publication date: May 5, 2011
    Inventors: Sebastian Bierwirth, Achim Hofmann, Hans-Peter Neumayer, Dieter Spitzenberger, Franz Fuerstenberger, Hannes Nuiding, Dieter Leier, Georg Schoenhuber, Joerg Friedrich
  • Publication number: 20110076251
    Abstract: This invention relates to the treatment of hepatitis infections or hepatitis diseases, in particular hepatitis C. The invention more particularly relates to the use of an inhibitor and/or repressor of a nucleic acid molecule, especially gene, which is related to the proliferation and/or replication of hepatitis viruses, in particular hepatitis C viruses, in order to produce a medicament for preventing and/or curing hepatitis, in particular hepatitis C, as well as a pharmaceutical composition, preferably for preventing or treating hepatitis C diseases, said composition containing the repressor and/or inhibitor.
    Type: Application
    Filed: March 12, 2009
    Publication date: March 31, 2011
    Inventor: Joerg Friedrich Schlaak
  • Publication number: 20090297852
    Abstract: A method for coating the surface of inorganic solid particles in an aqueous suspension, particularly for coating titanium dioxide with SiO2 includes: a) disagglomeration of the solid particles contained in aqueous suspension, b) addition of a water-soluble precursor of the coating substance to the suspension, c) immediately following step b) homogenization of the suspension, where the temperature and pH value of the suspension do not change significantly in steps a) to c), d) feeding the slurry into a tank and precipitation of the coating substance onto the particle surface and, optionally, application of further coatings, and e) separation of the solid particles from the suspension. The method produces to a highly homogeneous and continuous skin on the particle surface, and to less separately precipitated coating substance.
    Type: Application
    Filed: May 27, 2009
    Publication date: December 3, 2009
    Inventors: Heiko Frahm, Joerg Friedrich, Mark Kaminski, Erwin Schmeier, Lydia Drews-Nicolai, Volker Juergens
  • Publication number: 20090148364
    Abstract: A method for reprocessing cyclone dust occurring during the carbochlorination of titaniferous raw materials, which essentially consists of titanium dioxide, coke and other inert metal oxides, such as silicon dioxide, and for returning a coke-rich and/or a TiO2-rich fraction to the chlorination reactor includes: preparing an aqueous suspension of the cyclone dust; separating a coke-rich fraction (1) from the aqueous suspension by flotation; adding hydrofluoric acid to the remaining suspension; and separating a TiO2-rich fraction (2) by flotation from the remaining suspension.
    Type: Application
    Filed: November 13, 2008
    Publication date: June 11, 2009
    Inventors: Heiko Frahm, Joerg Friedrich, Dirk Floeder
  • Patent number: 7527272
    Abstract: A chuck is described, in particular for a hammer drill or chisel hammer, having a chuck body having an insertion opening for holding a tool shank, and a locking element for axially locking the tool shank in the insertion opening, the locking element being movable between a locked position and an unlocked position, and having an arresting pin, mounted in the locking element and radially displaceable between an arresting position and a release position, which axially arrests the locking element in its arresting position and axially releases it in its release position.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: May 5, 2009
    Assignee: Robert Bosch GmbH
    Inventors: Karl Frauhammer, Manfred Hellbach, Heinz Schnerring, Joerg Friedrich, Andreas Strasser, Michael Mayer, Werner Huser
  • Publication number: 20080282927
    Abstract: A gas generator has a propellant charge and an early ignition device held loosely in the propellant charge. The early ignition device consists of an early ignition charge and an enclosure surrounding the early ignition charge. The enclosure is at least one foil wrapped around the early ignition charge. The outer edges of the foil, lying one over another, are connected with each other to close the enclosure.
    Type: Application
    Filed: May 1, 2008
    Publication date: November 20, 2008
    Inventors: Georg Schoenhuber, Franz Fuerstenberger, Hans-Peter Neumayer, Joerg Friedrich, Helmut Schranner