Patents by Inventor Joerg Kaufmann

Joerg Kaufmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genes differentially expressed in breast cancer
    Publication number: 20020004239
    Abstract: A polynucleotide sequence as shown in SEQ ID NO:1 is associated with metastatic potential of cancer cells, especially breast cancer cells. Methods are provided for determining the risk of metastasis of a tumor, by determining whether a tissue sample from a tumor expresses a polypeptide or mRNA encoded by a polynucleotide as shown in SEQ ID NO:1. Also provided are therapeutic methods and compositions.
    Type: Application
    Filed: January 9, 2001
    Publication date: January 10, 2002
    Inventors: Joerg Kaufmann, Greg Harrowe, Christoph Reinhard, Sanmao Kang
  • cDNA molecule encoding human CIF130
    Patent number: 6303372
    Abstract: A human gene termed CIF130 and its expression products can alter the spatial or temporal patterns of mitosis or cell cycle progression of a human cell. Methods of treating disorders involving alterations in the regulation of mitosis or cell cycle progression utilize the gene and its expression product. Genes whose expression is dependent upon CIF130 expression can be identified.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: October 16, 2001
    Assignee: Chiron Corporation
    Inventor: Joerg Kaufmann
  • CIF150/hTAFII150 is necessary for cell cycle progression
    Patent number: 6174679
    Abstract: A human protein termed CIF150/hTAFII150 recognizes and selects TATA-less core promoters for cell cycle specific genes. Thus, CIF150/hTAFII150 plays an important and selective role in establishing gene expression patterns necessary for progression through the cell cycle. The CIF150/hTAFII150 gene and its expression products can be used to alter the spatial or temporal patterns of mitosis or cell cycle progression of a human cell and to treat disorders involving alterations in the regulation of mitosis or cell cycle progression.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: January 16, 2001
    Assignee: Chiron Corporation
    Inventor: Joerg Kaufmann