Abstract: A method and an arrangement are disclosed for modeling a mechatronic system in a motor vehicle in the context of an object-based ordering concept as a mapping in the unified modeling language. The elements of the CARTRONIC® with components and envelopes as their classes or objects and orders (with feedback), inquiries (with hint) and requests as their communication relationship are presented based on examples together with the essential rules from the overall control rules. A mapping requirement in the UML elements is shown for these modeling elements.

Abstract: A method is provided for repopulating degenerated of immunetolerant mice which lack mature B and T lymphocytes with xenogenic mammalian hepatocytes, particularly primate hepatocytes to generate chimeric mice. In addition, a method of generating a human hepatitis virus-infected chimeric mouse is provided. A preferred xenogenic primate hepatocyte is derived from human, chimpanzee or baboon. These chimeric mice are useful in the investigation of host and viral mechanisms determining hepadnaviral persistence and hepatocarcinogenesis. Methods for monitoring the development of hepatitis and hepatocellular carcinoma as well as methods for testing and screening anti-viral and anti-cancer compounds with this model system are also provided.

Abstract: A method is provided for repopulating degenerated of immunetolerant mice which lack mature B and T lymphocytes with xenogenic mammalian hepatocytes, particularly primate hepatocytes to generate chimeric mice. In addition, a method of generating a human hepatitis virus-infected chimeric mouse is provided. A preferred xenogenic primate hepatocyte is derived from human, chimpanzee or baboon. These chimeric mice are useful in the investigation of host and viral mechanisms determining hepadnaviral persistence and hepatocarcinogenesis. Methods for monitoring the development of hepatitis and hepatocellular carcinoma as well as methods for testing and screening anti-viral and anti-cancer compounds with this model system are also provided.

Abstract: A method and an arrangement are disclosed for modeling a mechatronic system in a motor vehicle in the context of an object-based ordering concept as a mapping in the unified modeling language. The elements of the CARTRONIC® with components and envelopes as their classes or objects and orders (with feedback), inquiries (with hint) and requests as their communication relationship are presented based on examples together with the essential rules from the overall control rules. A mapping requirement in the UML elements is shown for these modeling elements.

Abstract: The present invention relates to administration forms having a relatively long gastric residence time, in the preparation of which mixtures of polymers containing lactam groups and polymers containing carboxyl groups are used, and which are distinguished both by marked swelling properties and by high dimensional stability in the swollen state.

Abstract: Substituted triols are prepared by reducing appropriately substituted carboxylic esters. The substituted triols can be used as active substances in medicaments.