Patents by Inventor Joerg WIRTHS

Joerg WIRTHS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the hydrolysis of quinolonecarboxylic esters
    Patent number: 11332444
    Abstract: Quinolonecarboxylic esters of the general formula (II) are hydrolyzed to quinolonecarboxylic acids of the general formula (I): The method comprises the step A): A) reacting compounds of the formula (II) with a mixture comprising acetic acid, sulfuric acid and water In step A), ?30 to ?40 mol of acetic acid, ?0.3 to ?1 mol of sulfuric acid and ?0.9 to ?2.5 mol of water are used per mole of compounds of the formula (II). The method is particularly suitable for the synthesis of the intermediate (I) in the synthesis of pradofloxacin.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: May 17, 2022
    Assignee: Bayer Animal Health GmbH
    Inventors: Peter Fey, Mathias Berwe, Joerg Wirths, Ralf Wischnat, Markus Longerich, Antje Dietzel
  • METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS
    Publication number: 20210078950
    Abstract: Quinolonecarboxylic esters of the general formula (II) are hydrolyzed to quinolonecarboxylic acids of the general formula (I): The method comprises the step A): A) reacting compounds of the formula (II) with a mixture comprising acetic acid, sulfuric acid and water In step A), ?30 to ?40 mol of acetic acid, ?0.3 to ?1 mol of sulfuric acid and ?0.9 to ?2.5 mol of water are used per mole of compounds of the formula (II). The method is particularly suitable for the synthesis of the intermediate (I) in the synthesis of pradofloxacin.
    Type: Application
    Filed: April 18, 2019
    Publication date: March 18, 2021
    Inventors: Peter FEY, Mathias BERWE, Joerg WIRTHS, Raif WISCHNAT, Markus LONGERICH, Antje DIETZEL