Patents by Inventor Joey M STUDTS

Joey M STUDTS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production host cell lines
    Patent number: 8962312
    Abstract: The invention concerns the field of cell culture technology. The invention describes production host cell lines comprising vector constructs comprising a DHFR expression cassette. Those cell lines have improved growth characteristics in comparison to DHFR-deficient or DHFR-reduced cell lines such as CHO DG44 and CHO DUKX-B11. The invention especially concerns two cell lines, a representative of each cell line is deposited with the DSMZ under the number DSM ACC2909 (CHOpper® Discovery) and DSM ACC2910 (CHOpper® Standard). The invention further concerns a method of producing proteins using the cells generated by the described method.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: February 24, 2015
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Hitto Kaufmann, Lore Florin, Eric Becker, Joey M. Studts
  • PRODUCTION HOST CELL LINES
    Publication number: 20100021911
    Abstract: The invention concerns the field of cell culture technology. The invention describes production host cell lines comprising vector constructs comprising a DHFR expression cassette. Those cell lines have improved growth characteristics in comparison to DHFR-deficient or DHFR-reduced cell lines such as CHO DG44 and CHO DUKX-B11. The invention especially concerns two cell lines, a representative of each cell line is deposited with the DSMZ under the number DSM ACC2909 (CHOpper® Discovery) and DSM ACC2910 (CHOpper® Standard). The invention further concerns a method of producing proteins using the cells generated by the described method.
    Type: Application
    Filed: July 22, 2009
    Publication date: January 28, 2010
    Applicant: BOEHRINGER INGELHEIM PHARMA GMBH & CO KG
    Inventors: Hitto KAUFMANN, Lore FLORIN, Eric BECKER, Joey M. STUDTS
  • SM-PROTEIN BASED SECRETION ENGINEERING
    Publication number: 20090247609
    Abstract: The present invention concerns the field of cell culture technology. It describes a novel method for enhancing the secretory transport of proteins in eukaryotic cells by heterologous expression of Munc18c, Sly1 or other members of the SM protein family. This method is particularly useful for the generation of optimized host cell systems with enhanced production capacity for the expression and manufacture of recombinant protein products.
    Type: Application
    Filed: December 17, 2008
    Publication date: October 1, 2009
    Inventors: Hitto KAUFMANN, Eric BECKER, Lore FLORIN, Martin FUSSENEGGER, Ren-Wang PENG, Joey M STUDTS