Patents by Inventor Johan Botterman

Johan Botterman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7893325
    Abstract: The invention relates to fungal disease resistance, in particular to resistance to blackleg disease caused by Leptosphaeria maculans. Provided are Brassica plants and seeds comprising a fragment of chromosome 8 of a wild B. rapa accession in their genome, wherein this fragment comprises a blackleg resistance locus. Further provided are molecular markers linked to the blackleg resistance locus and methods of using the markers. Brassica plants and seeds with stacked blackleg resistance loci are also provided.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: February 22, 2011
    Assignee: Bayer BioScience N.V.
    Inventors: Elke Diederichsen, Benjamin Laga, Johan Botterman
  • Patent number: 7501559
    Abstract: Plants made resistant to insects by transforming their nuclear genome with two or more DNA sequences, each encoding a different non-competitively binding B. thuringiensis protoxin or insecticidal part thereof, preferably the toxin thereof.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: March 10, 2009
    Assignee: Bayer BioScience N.V.
    Inventors: Herman Van Mellaert, Johan Botterman, Jeroen Van Rie, Henk Joos
  • Publication number: 20070150983
    Abstract: Plants made resistant to insects by transforming their nuclear genome with two or more DNA sequences, each encoding a different non-competitively binding B. thuringiensis protoxin or insecticidal part thereof, preferably the toxin thereof.
    Type: Application
    Filed: November 9, 2006
    Publication date: June 28, 2007
    Applicant: Bayer BioScience, N.V.
    Inventors: Herman Van Mellaert, Johan Botterman, Jeroen Van Rie, Henk Joos
  • Patent number: 7112665
    Abstract: The invention relates to a DNA fragment containing a determined gene, the expression of which inhibits the antibiotic and herbicidal effects of Bialaphos and related products. It also relates to recombinant vectors, containing such DNA fragment, which enable this protective gene to be introduced and expressed into cells and plant cells.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: September 26, 2006
    Assignees: Bayer BioScience N.V., Biogen, Inc.
    Inventors: Jan Leemans, Johan Botterman, Marc De Block, Charles Thompson, Rao Mouva
  • Publication number: 20050142122
    Abstract: The invention relates to fungal disease resistance, in particular to resistance to blackleg disease caused by Leptosphaeria maculans. Provided are Brassica plants and seeds comprising a fragment of chromosome 8 of a wild B. rapa accession in their genome, wherein this fragment comprises a blackleg resistance locus. Further provided are molecular markers linked to the blackleg resistance locus and methods of using the markers. Brassica plants and seeds with stacked blackleg resistance loci are also provided.
    Type: Application
    Filed: December 23, 2004
    Publication date: June 30, 2005
    Inventors: Elke Diederichsen, Benjamin Laga, Johan Botterman
  • Patent number: 6855873
    Abstract: Plants made resistant to insects by transforming their nuclear genome with two or more DNA sequences, each encoding a different non-competitively binding B. thuringiensis protoxin or insecticidal part thereof, preferably the toxin thereof.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: February 15, 2005
    Assignee: Bayer BioScience, N.V.
    Inventors: Herman Van Mellaert, Johan Botterman, Jeroen Van Rie, Henk Joos
  • Patent number: 6797861
    Abstract: “The present invention relates to DNA sequences, comprising nucleic acid fragments encoding dehiscence zone-selective proteins, particularly cell wall hydrolases such as polygalacturonases, and their use for modifying dehiscence properties in plants, more particularly pod dehiscence properties in Brassica napus.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: September 28, 2004
    Assignee: Bayer BioScience NV
    Inventors: Peter Ulvskov, Robin Child, Henri Van Onckelen, Els Prinsen, Bernhard Borkhardt, Lilli Sander, Morten Petersen, Gert Bundgard Poulsen, Johan Botterman
  • Publication number: 20040181825
    Abstract: Plants made resistant to insects by transforming their nuclear genome with two or more DNA sequences, each encoding a different non-competitively binding B. thuringiensis protoxin or insecticidal part thereof, preferably the toxin thereof.
    Type: Application
    Filed: March 26, 2004
    Publication date: September 16, 2004
    Applicant: Bayer BioScience N.V.
    Inventors: Herman Van Mellaert, Johan Botterman, Jeroen Van Rie, Henk Joos
  • Publication number: 20020184660
    Abstract: A plant is provided which contains at least one dehiscence zone (DZ)-selective chimeric gene incorporated in the nuclear genome of its cells, wherein said DZ-selective chimeric gene comprises the following operably linked DNA fragments:
    Type: Application
    Filed: May 21, 2002
    Publication date: December 5, 2002
    Applicant: Plant Genetic Systems, N.V.
    Inventors: Peter Ulvskov, Robin Child, Henri Van Onckelen, Els Prinsen, Bernhard Borkhardt, Lilli Sander, Morten Petersen, Gert Bundgard Poulsen, Johan Botterman
  • Patent number: 6420628
    Abstract: A plant is provided which contains at least one dehiscence zone (DZ)-selective chimeric gene incorporated in the nuclear genome of its cells, wherein said DZ-selective chimeric gene comprises the following operably linked DNA fragments: a) a transcribed DNA region encoding: 1) a RNA which, when produced in cells of a particular DZ of the plant, prevents, inhibits or reduces the expression in DZ cells of an endogenous gene of the plant encoding a cell wall hydrolase, particularly an endopolygalacturonase, or, 2) a protein or polypeptide, which when produced in DZ cells, kills or disables them or interferes with their normal metabolism, physiology or development; b) a plant expressible promoter which directs expression of transcribed DNA region at least in DZ cells, provided that if transcribed DNA region encodes a protein or polypeptide, or encodes an antisense RNA or ribozyme directed to a sense RNA encoded by an endogenous gene that is expressed in plant in cells other than DZ cells, plant expressible promot
    Type: Grant
    Filed: September 28, 1998
    Date of Patent: July 16, 2002
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Peter Ulvskov, Robin Child, Henri Van Onckelen, Els Prinsen, Bernhard Borkhardt, Lilli Sander, Morten Petersen, Gert Bundgard Poulsen, Johan Botterman
  • Patent number: 6344602
    Abstract: A plant having in the nuclear genome of its cells foreign DNA comprising i) a male-sterility gene comprising a male-sterility DNA encoding a sterility RNA, protein or polypeptide which, when produced or overproduced in a stamen cell of the plant, significantly disturbs the metabolism, functioning and/or development of the stamen cell, and, a sterility promoter directing expression of the male-sterility DNA selectively in specific stamen cells of said plant, the male-sterility DNA being in the same transcriptional unit as, and under the control of, the sterility promoter, and ii) a coregulating gene comprising a coregulating DNA encoding a coregulating RNA, protein or polypeptide which, when produced in plant cells wherein said sterility RNA, protein or polypeptide is produced, prevents the activity of said sterility RNA, protein or polypeptide, and a coregulating promoter which is selected from the group consisting of a promoter directing expression of said coregulating DNA in non-stamen cells of said plant,
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: February 5, 2002
    Assignee: Aventis CropScience N.V.
    Inventors: Frank Michiels, Johan Botterman, Marc Cornelissen
  • Patent number: 6172281
    Abstract: Plants made resistant to insects by transforming their nuclear genome with two or more DNA sequences, each encoding a different non-competitively binding B. thuringiensis protoxin or insecticidal part thereof, preferably the toxin thereof.
    Type: Grant
    Filed: October 22, 1998
    Date of Patent: January 9, 2001
    Assignee: Aventis CropScience N.V.
    Inventors: Herman Van Mellaert, Johan Botterman, Jeroen Van Rie, Henk Joos
  • Patent number: 6025546
    Abstract: A plant having in the nuclear genome of its cells foreign DNA comprisinga male-sterility gene comprising:a male-sterility DNA encoding a sterility RNA, protein or polypeptide which, when produced or overproduced in a stamen cell of the plant, significantly disturbs the metabolism, functioning and/or development of the stamen cell, and,a sterility promoter directing expression of the male-sterility DNA selectively in specific stamen cells of said plant, the male-sterility DNA being in the same transcriptional unit as, and under the control of, the sterility promoter, anda coregulating gene comprising:a coregulating DNA encoding a coregulating RNA, protein or polypeptide which is capable, when produced in plant cells wherein said sterility RNA, protein or polypeptide is produced, of sufficiently preventing the activity of said sterility RNA, protein or polypeptide,whereby said coregulating DNA is in a transcriptional unit which is different from the transcriptional unit of said sterility DNA.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: February 15, 2000
    Assignee: Plant Genetic System, N.V.
    Inventors: Frank Michiels, Johan Botterman, Marc Cornelissen
  • Patent number: 5908970
    Abstract: Plants made resistant to insects by transforming their nuclear genome with two or more DNA sequences, each encoding a different non-competitively binding B. thuringiensis protoxin or insecticidal part thereof, preferably the toxin thereof.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 1, 1999
    Assignee: Plant Genetic Systems N.V.
    Inventors: Herman Van Mellaert, Johan Botterman, Jeroen Van Rie, Henk Joos
  • Patent number: 5866784
    Abstract: Plants made resistant to insects by transforming their nuclear genome with two or more DNA sequences, each encoding a different non-competitively binding B. thuringiensis protoxin or insecticidal part thereof, preferably the toxin thereof.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: February 2, 1999
    Assignee: Plant Genetic Systems N.V.
    Inventors: Herman Van Mellaert, Johan Botterman, Jeroen Van Rie, Henk Joos
  • Patent number: 5648477
    Abstract: The invention relates to a DNA fragment containing a determined gene, the expression of which inhibits the antibiotic and herbicidal effects of Bialaphos and related products.It also relates to recombinant vectors, containing such DNA fragment, which enable this protective gene to be introduced and expressed into cells and plant cells.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 15, 1997
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Jan Leemans, Johan Botterman, Charles Thompson, Rao Mouva
  • Patent number: 5646024
    Abstract: The invention relates to a DNA fragment containing a determined gene, the expression of which inhibits the antibiotic and herbicidal effects of Bialaphos and related products.It also relates to recombinant vectors, containing such DNA fragment, which enable this protective gene to be introduced and expressed into cells and plant cells.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: July 8, 1997
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Jan Leemans, Johan Botterman, Marc De Block, Charles Thompson, Rao Mouva
  • Patent number: 5561236
    Abstract: The invention relates to a DNA fragment containing a determined gene, the expression of which inhibits the antibiotic and herbicidal effects of Bialaphos and related products.It also relates to recombinant vectors, containing such DNA fragment, which enable this protective gene to be introduced and expressed into cells and plant cells.
    Type: Grant
    Filed: May 17, 1990
    Date of Patent: October 1, 1996
    Assignees: Plant Genetic Systems, Biogen, Inc.
    Inventors: Jan Leemans, Johan Botterman, Marc De Block, Charles Thompson, Rao Mouva
  • Patent number: 5460963
    Abstract: A plant cell transformed with all or part of a Bacillus thuringiensis gene coding for either a 130 or 132 kDa protoxin against Lepidoptera, preferably with a part of the gene coding just for the respective 62 or 60 kDa trypsin-digestion product of the protoxin. A plant, regenerated from the transformed cell, is resistant to Lepidoptera.
    Type: Grant
    Filed: September 24, 1992
    Date of Patent: October 24, 1995
    Assignee: Plant Genetic Systems, N.V.
    Inventors: Johan Botterman, Marnix Peferoen, Herman Hofte, Henk Joos
  • Patent number: RE44962
    Abstract: The invention relates to a DNA fragment containing a determined gene, the expression of which inhibits the antibiotic and herbicidal effects of Bialaphos and related products. It also relates to recombinant vectors, containing such DNA fragment, which enable this protective gene to be introduced and expressed into cells and plant cells.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: June 24, 2014
    Assignees: Bayer Cropscience N.V., Biogen Idec MA Inc.
    Inventors: Jan Leemans, Johan Botterman, Marc De Block, Charles Thompson, Rao Mouva