Patents by Inventor Johan D. Oslob

Johan D. Oslob has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF CELLULAR ADHESION
    Publication number: 20210145824
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1-R4, n, p, A, B, D, E, L and AR1 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1).
    Type: Application
    Filed: July 27, 2020
    Publication date: May 20, 2021
    Applicant: NOVARTIS PHARMACEUTICALS CORPORATION
    Inventors: Wang SHEN, Kenneth BARR, Johan D. OSLOB, Min ZHONG
  • MODULATORS OF CELLULAR ADHESION
    Publication number: 20190134022
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1-R4, n, p, A, B, D, E, L and AR1 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1).
    Type: Application
    Filed: October 26, 2018
    Publication date: May 9, 2019
    Applicant: SARcode Bioscience Inc.
    Inventors: Wang SHEN, Kenneth BARR, Johan D. OSLOB, Min ZHONG
  • Heterocyclic modulators of lipid synthesis and combinations thereof
    Patent number: 10226449
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: March 12, 2019
    Assignee: 3-V Biosciences, Inc.
    Inventors: Timothy Sean Heuer, Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Gregory Duke, Yamini Ohol-Gupta, Marie O'Farrell
  • Heterocyclic modulators of lipid synthesis
    Patent number: 10189822
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: January 29, 2019
    Assignee: 3-V Biosciences, Inc.
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Gregory Duke, Yamini Ohol-Gupta, Timothy Sean Heuer, Marie O'Farrell
  • Modulators of cellular adhesion
    Patent number: 10124000
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1-R4, n, p, A, B, D, E, L and AR1 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1).
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: November 13, 2018
    Assignee: SARCODE BIOSCIENCE INC.
    Inventors: Wang Shen, Kenneth Barr, Johan D. Oslob, Min Zhong
  • Heterocyclic modulators of lipid synthesis
    Patent number: 10118913
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: November 6, 2018
    Assignee: 3-V Biosciences, Inc.
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Allan S. Wagman
  • Heterocyclic modulators of lipid synthesis
    Patent number: 10053450
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.
    Type: Grant
    Filed: July 5, 2016
    Date of Patent: August 21, 2018
    Assignee: 3-V Biosciences, Inc.
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Allan S. Wagman
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20180222892
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.
    Type: Application
    Filed: March 30, 2018
    Publication date: August 9, 2018
    Inventors: Johan D. OSLOB, Robert S. MCDOWELL, Russell JOHNSON, Hanbiao YANG, Marc EVANCHIK, Cristiana A. ZAHARIA, Haiying CAI, Lily W. HU, Allan S. WAGMAN
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20180079746
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders.
    Type: Application
    Filed: March 15, 2016
    Publication date: March 22, 2018
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Gregory Duke, Yamini Ohol-Gupta, Timothy Sean Heuer, Marie O'Farrell
  • Heterocyclic modulators of lipid synthesis
    Patent number: 9809591
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: November 7, 2017
    Assignee: 3-V Biosciences, Inc.
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu
  • Heterocyclic modulators of lipid synthesis
    Patent number: 9624173
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: April 18, 2017
    Assignee: 3-V Biosciences, Inc.
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS AND COMBINATIONS THEREOF
    Publication number: 20160338998
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.
    Type: Application
    Filed: December 19, 2014
    Publication date: November 24, 2016
    Applicant: 3-V Biosciences, Inc.
    Inventors: Timothy Sean Heuer, Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Gregory Duke, Yamini Ohol, Marie O'Farrell
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20160311803
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.
    Type: Application
    Filed: July 5, 2016
    Publication date: October 27, 2016
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Allan S. Wagman
  • Heterocyclic modulators of lipid synthesis
    Patent number: 9428502
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: August 30, 2016
    Assignee: 3-V Biosciences, Inc.
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Allan S. Wagman
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20160102091
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders.
    Type: Application
    Filed: October 5, 2015
    Publication date: April 14, 2016
    Applicant: 3-V BIOSCIENCES, INC.
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu
  • MODULATORS OF CELLULAR ADHESION
    Publication number: 20160074381
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1-R4, n, p, A, B, D, E, L and AR1 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1).
    Type: Application
    Filed: November 12, 2015
    Publication date: March 17, 2016
    Applicant: SARcode Bioscience Inc.
    Inventors: Wang SHEN, Kenneth BARR, Johan D. OSLOB, Min ZHONG
  • Modulators of cellular adhesion
    Patent number: 9248126
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1-R4, n, p, A, B, D, E, L and AR1 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1).
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: February 2, 2016
    Assignee: SARCODE BIOSCIENCE INC.
    Inventors: Wang Shen, Kenneth Barr, Johan D. Oslob, Min Zhong
  • Modulators of cellular adhesion
    Patent number: 9216174
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1-R4, n, p, A, B, D, E, L and AR1 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1).
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: December 22, 2015
    Assignee: SARCODE BIOSCIENCE INC.
    Inventors: Wang Shen, Kenneth Barr, Johan D. Oslob, Min Zhong
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20150259292
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatits C infection, cancer and metabolic disorders.
    Type: Application
    Filed: March 19, 2015
    Publication date: September 17, 2015
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20150210688
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.
    Type: Application
    Filed: December 31, 2014
    Publication date: July 30, 2015
    Inventors: Johan D. OSLOB, Robert S. MCDOWELL, Russell JOHNSON, Hanbiao YANG, Mark EVANCHIK, Cristiana A. ZAHARIA, Haiying CAI, Lily W. HU