Abstract: Methods, systems, and devices include locating one or more target structures comprised in an eye of a patient based on processing image data of the eye of the patient, determining one or more measurements associated with an anterior portion of the eye based on the location data, and determining a presence, an absence, a progression, or a stage of a disease of the eye based on the one or more measurements. Locating the one or more target structures may be based on an output provided by a machine learning model.

Abstract: The present disclosure is directed to a system and method that detects and measures a vault of an anterior segment of an eye of a patient. The system and method locate an implanted contact lens (ICL) between a cornea and a natural lens, form a B-scan of the eye based on the received ultrasound pulses, removes background pixels, such as by binarizing and thresholding, from the B-Scan from a grayscale color palette to a black/white color palette, determines, from the resulting B-scan a fiduciary location in the anterior segment of the eye, and forms using the resulting B-scan and fiduciary location, a vault map mapping a distance between an anterior segment surface and a posterior surface of the ICL along a plurality of lines drawn perpendicular to a local surface of the anterior segment surface.

Abstract: A medical imaging method is described for establishing implant configuration by measuring the positions and orientations of its components constrained by a defined kinematic relationship between them using stereo radiography images. The method allows the determination of a patient-specific implant configuration and enables accurate measurements of the pose of implant despite significant occlusions. The measurements obtained with this method can be used to determine the relative movement of an implant component relative to other components, bone or other landmark.

Abstract: The present invention relates to a device and use of the device for detection and loosening of implants installed into a subject's host bone, the device comprising: a frame for encircling and demountably engaging a portion of the subject's appendage comprising the host bone with installed implant; and at least three-spaced apart attachments engaged with the frame, wherein each attachment is configured to house and to retractably deploy a sharp geometry component for contacting the host bone, wherein a temporary reference frame is created when the three-spaced apart attachments contact the host bone. The use of the device comprises obtaining a first pair of stereo radiographs of the implant under a first loading condition and obtaining a second pair of stereo radiographs of the implant and host bone area under the second loading condition and comparing the two radiographs to detect displacement of the implant.

Abstract: Diagnostic systems and methods for measuring and assessing spine instability are described which involve reconstruction of a dynamic three-dimensional model of a patient's spine moving through a range of motions, and optimization of the three-dimensional model to provide relative three-dimensional position and orientation data for each vertebra in the spine throughout the motion. Vertebral movement is thereby accurately measured and instability determined for presentation in a user-friendly form.

Abstract: This disclosure describes systems, methods, and apparatus for generating a 3D rendering of and quantitative analysis of biochemical MRI voxels corresponding to a tissue or organ of interest. Voxels corresponding to the tissue or organ of interest can be identified from anatomical MRI voxels and aligned with biochemical MRI voxels. The biochemical MRI voxels aligned with the tissue or organ of interest can be isolated and then provided to one or more modules for 3D rendering and quantitative analysis.

Abstract: A method for constructing a dual fluoroscopy system according to embodiments of the present invention includes providing a first c-arm and a second c-arm, each of which include an x-ray generator and an imaging device, synchronizing exposure timing of the two x-ray generators, decoupling the x-ray generators from the imaging devices and mounting them on a gantry system, aligning one x-ray generator with an imaging device and aligning the other x-ray generator with the other imaging device, and performing a calibration test to determine the dual fluoroscopy system configuration, and attaching a triggering and visualization device. An imaging system of the imaging device may be upgraded to permit faster data capture rates, according to embodiments of the present invention.