Patents by Inventor Johan F. M. Gijsbers

Johan F. M. Gijsbers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040073099
    Abstract: Medical disorders with a neurological origin may be treated by modifying the ion concentration of brain fluid in the brain of a patient. The ion concentration of the fluid of the brain may be modified by delivering fluid to the brain, the ion concentration of the delivered fluid being such as to cause the ion concentration in the brain to be modified. The method may include replacing brain fluid, and may include replacing such fluid with fluid previously extracted from the brain. Epilepsy and other neurological disorders that are affected by the electrical potential difference between intracellular fluid and extra-cellular fluid and therefore the cell membrane potentials, and therefore the thresholds for the communication between brain cells can be controlled by re-circulating extra cellular brain fluid after the fluid has been treated to alter its ion concentrations.
    Type: Application
    Filed: August 20, 2003
    Publication date: April 15, 2004
    Applicant: Medtronic, Inc.
    Inventors: Johan F.M. Gijsbers, Frans L.H. Gielen
  • Patent number: 6709426
    Abstract: Epilepsy and other neurological disorders that are affected by the electrical potential difference between intracellular fluid and extra-cellular fluid and therefore the cell membrane potentials, and therefore the thresholds for the communication between brain cells can be controlled by re-circulating extra-cellular brain fluid after the fluid has been treated to alter its ion concentrations. A computer-controlled pump can precisely control the extraction and delivery of brain fluid after the ion concentration of the fluid is appropriately adjusted, e.g. guided by the Goldmann equation. Well-known techniques for modifying ion concentrations can be used to raise or lower ion concentrations as needed.
    Type: Grant
    Filed: June 18, 2002
    Date of Patent: March 23, 2004
    Assignee: Medtronic, Inc.
    Inventors: Johan F. M. Gijsbers, Frans L. H. Gielen
  • Patent number: 6551301
    Abstract: Epilepsy and other neurological disorders that are affected by the electrical potential difference between intracellular fluid and extra-cellular fluid and therefore the cell membrane potentials, and therefore the thresholds for the communication between brain cells can be controlled by re-circulating extra-cellular brain fluid after the fluid has been treated to alter its ion concentrations. A computer-controlled pump can precisely control the extraction and delivery of brain fluid after the ion concentration of the fluid is appropriately adjusted, e.g. guided by the Goldmann equation. Well-known techniques for modifying ion concentrations can be used to raise or lower ion concentrations as needed.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: April 22, 2003
    Assignee: Medtronic Inc.
    Inventors: Johan F. M. Gijsbers, Frans L. H. Gielen
  • Publication number: 20020161350
    Abstract: Epilepsy and other neurological disorders that are affected by the electrical potential difference between intracellular fluid and extra-cellular fluid and therefore the cell membrane potentials, and therefore the thresholds for the communication between brain cells can be controlled by re-circulating extra-cellular brain fluid after the fluid has been treated to alter its ion concentrations. A computer-controlled pump can precisely control the extraction and delivery of brain fluid after the ion concentration of the fluid is appropriately adjusted, e.g. guided by the Goldmann equation. Well-known techniques for modifying ion concentrations can be used to raise or lower ion concentrations as needed.
    Type: Application
    Filed: June 18, 2002
    Publication date: October 31, 2002
    Applicant: Medtronic, Incorporated
    Inventors: Johan F.M. Gijsbers, Frans L.H. Gielen
  • Publication number: 20020128589
    Abstract: Epilepsy and other neurological disorders that are affected by the electrical potential difference between intracellular fluid and extra-cellular fluid and therefore the cell membrane potentials, and therefore the thresholds for the communication between brain cells can be controlled by re-circulating extra-cellular brain fluid after the fluid has been treated to alter its ion concentrations. A computer-controlled pump can precisely control the extraction and delivery of brain fluid after the ion concentration of the fluid is appropriately adjusted, e.g. guided by the Goldmann equation. Well-known techniques for modifying ion concentrations can be used to raise or lower ion concentrations as needed.
    Type: Application
    Filed: May 8, 2002
    Publication date: September 12, 2002
    Applicant: Medtronic, Inc.
    Inventors: Johan F.M. Gijsbers, Frans L.H. Gielen
  • Patent number: 6447500
    Abstract: Epilepsy and other neurological disorders that are affected by the electrical potential difference between intracellular fluid and extra-cellular fluid and therefore the cell membrane potentials, and therefore the thresholds for the communication between brain cells can be controlled by re-circulating extra-cellular brain fluid after the fluid has been treated to alter its ion concentrations. A computer-controlled pump can precisely control the extraction and delivery of brain fluid after the ion concentration of the fluid is appropriately adjusted, e.g. guided by the Goldmann equation. Well-known techniques for modifying ion concentrations can be used to raise or lower ion concentrations as needed.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: September 10, 2002
    Assignee: Medtronic, Inc.
    Inventors: Johan F. M. Gijsbers, Frans L. H. Gielen