Patents by Inventor Johan Garssen

Johan Garssen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150164931
    Abstract: We describe a composition comprising a non-digestible oligosaccharide for the treatment, prevention or alleviation of a trichothecene mycotoxin exposure associated condition. The non-digestible oligosaccharide may comprise a galactooligosaccharide and/or fructooligosaccharide. The non-digestible oligosaccharide may comprise a short chain galacto-oligosaccharide (scGOS) and/or short chain fructooligosaccharide (scFOS). The trichothecene mycotoxin exposure associated condition may be associated with exposure to deoxynivalenol.
    Type: Application
    Filed: May 17, 2013
    Publication date: June 18, 2015
    Applicant: N.V. Nutricia
    Inventors: Johan Garssen, Hermiena Christina Schoterman, Johanna Fink-Gremmels, Saskia Braber
  • Publication number: 20150080334
    Abstract: There is provided compositions and methods for enhancing an immune system and/or preventing an immune system related disorder in a mammalian subject, the composition comprising a non-digestible oligosaccharide which is to be administered to a female who is breast-feeding the mammalian subject.
    Type: Application
    Filed: February 10, 2012
    Publication date: March 19, 2015
    Applicant: N.V. NUTRICIA
    Inventors: Johan Garssen, Astrid Hogenkamp, Elisabeth Catharina Adriana Maria Van Esch, Leon Matthieu Johannes Knippels
  • Publication number: 20140335129
    Abstract: Compositions and methods for providing infant nutrition with partially hydrolysed proteins and non-digestible oligosaccharides for use in induction of oral tolerance against native dietary proteins.
    Type: Application
    Filed: July 21, 2014
    Publication date: November 13, 2014
    Inventors: Léon Mathieu Johannes Knippels, Elisabeth Catharina Adriana Maria van Esch, Johan Garssen
  • Publication number: 20140303067
    Abstract: The present invention provides a method for the treatment of eosinophilicesophagitis comprising administering non-digestible oligosaccharides.
    Type: Application
    Filed: October 6, 2011
    Publication date: October 9, 2014
    Inventors: Johan Garssen, Christophe Dupont, Catharina Theresia Knipping
  • Publication number: 20140296179
    Abstract: The present invention provides a method and composition for the treatment and/or prevention of infection, said method comprising orally administering a composition to a mammal, said composition comprising a galactose containing indigestible oligosaccharide and immunoglobulin from the milk or colostrum of hyperimmunized cows.
    Type: Application
    Filed: March 5, 2014
    Publication date: October 2, 2014
    Applicant: N.V. NUTRICIA
    Inventors: Günther BOEHM, Laura M'RABET, Bernd STAHL, Johan GARSSEN, Antony William SCAMMELL, Raymonde Peter PEETERS
  • Patent number: 8729123
    Abstract: The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and to a corresponding composition. Said composition comprises a n-3 polyunsaturated fatty acid fraction containing at least 0.1 wt % docosahexaenoic acid (DHA) based on total weight of the lipid, at least 0.01 wt % n-3 docosapentaenoic acid (DPAn-3) based on total weight of the lipid, and at least 0.01 wt. % eicosapentaenoic acid (EPA) based on total weight of the lipid, wherein the sum of DHA, DPAn-3 and EPA is below 1 wt. % of total lipid.
    Type: Grant
    Filed: October 3, 2011
    Date of Patent: May 20, 2014
    Assignee: N.V. Nutricia
    Inventors: Bernd Stahl, Gunther Boehm, Christopher Beermann, Johan Garssen
  • Patent number: 8580316
    Abstract: A nutritional or pharmaceutical composition comprising fat, protein, carbohydrate, whey and casein is provided. The composition has a weight ratio of casein to whey between 1:1 to 1:2.4 and comprises: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids selected from docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and 2 to 12 grams indigestible oligosaccharides having a degree of polymerisation of 2 to 100 per 100 gram dry weight of the composition. Methods of treatment by administering the composition are also provided.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: November 12, 2013
    Assignee: N. V. Nutricia
    Inventors: Günther Boehm, Christopher Beermann, Bernd Stahl, Laura M'Rabet, Johan Garssen
  • Patent number: 8557794
    Abstract: The present invention relates to a method for enhancing the immune system and the treatment and/or prevention of immune system related disorders in a mammal, particularly newborns, said method comprising the administration of acid oligosaccharide and neutral oligosaccharide. Food compositions suitable for use in the above method are also provided.
    Type: Grant
    Filed: October 25, 2004
    Date of Patent: October 15, 2013
    Assignee: N.V. Nutricia
    Inventors: Bernd Stahl, Laura M'Rabet, Arjan Paul Vos, Johan Garssen, Günther Boehm
  • Publication number: 20130143799
    Abstract: Compositions and methods for providing infant nutrition with partially hydrolysed proteins and non-digestible oligosaccharides for use in induction of oral tolerance against native dietary proteins.
    Type: Application
    Filed: June 1, 2011
    Publication date: June 6, 2013
    Inventors: Léon Mathieu Johannes Knippels, Elisabeth Catharina Adriana Maria Van Esch, Johan Garssen
  • Publication number: 20130136769
    Abstract: Compositions and methods for providing infant nutrition with partially hydrolysed proteins and non-digestible oligosaccharides for use in induction of oral tolerance against native dietary proteins.
    Type: Application
    Filed: June 1, 2011
    Publication date: May 30, 2013
    Inventors: Léon Mathieu Johannes Knippels, Elisabeth Catharina Adriana Maria Van Esch, Johan Garssen
  • Publication number: 20130102560
    Abstract: The present invention provides a method and composition for the treatment and/or prevention of infection, said method comprising orally administering a composition to a mammal, said composition comprising a galactose containing indigestible oligosaccharide and immunoglobulin from the milk or colostrum of hyperimmunized cows.
    Type: Application
    Filed: September 14, 2012
    Publication date: April 25, 2013
    Inventors: Günther Boehm, Laura M'Rabet, Bernd Stahl, Johan Garssen, Antony William Scammell, Raymonde Peter Peeters
  • Patent number: 8277835
    Abstract: The present invention provides a method and composition for the treatment and/or prevention of infection, said method comprising orally administering a composition to a mammal, said composition comprising a galactose containing indigestible oligosaccharide and immunoglobulin from the milk or colostrum of hyperimmunized cows.
    Type: Grant
    Filed: August 24, 2005
    Date of Patent: October 2, 2012
    Assignee: N. V. Nutricia
    Inventors: Günther Boehm, Laura M'Rabet, Bernd Stahl, Johan Garssen, Antony William Scammell, Raymonde Peter Peeters
  • Publication number: 20120195975
    Abstract: A nutritional or pharmaceutical composition comprising fat, protein, carbohydrate, whey and casein is provided. The composition has a weight ratio of casein to whey between 1:1 to 1:2.4 and comprises: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids selected from docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and f) 2 to 12 grams indigestible oligosaccharides having a degree of polymerisation of 2 to 100 per 100 gram dry weight of the composition. Methods of treatment by administering the composition are also provided.
    Type: Application
    Filed: January 27, 2012
    Publication date: August 2, 2012
    Inventors: Günther Boehm, Christopher Beermann, Bernd Stahl, Laura M'Rabet, Johan Garssen
  • Publication number: 20120178674
    Abstract: Nutritional compositions with fucosyllactose and betagalactooligosaccharides for use in stimulation of the immune system. The composition is suitable for infants.
    Type: Application
    Filed: July 12, 2010
    Publication date: July 12, 2012
    Inventors: Bernd Stahl, Alma Jildou Nauta, Johan Garssen, Eric Samain, Sophie Drouillard
  • Publication number: 20120177691
    Abstract: The invention concerns nutritional compositions with fucosyllactose for use in stimulation of NK cells. The composition is suitable for infants.
    Type: Application
    Filed: July 12, 2010
    Publication date: July 12, 2012
    Inventors: Bernd Stahl, Alma Jildou Nauta, Johan Garssen, Eric Samain, Sophie Drouillard
  • Publication number: 20120122813
    Abstract: The present invention relates to oligosaccharide mixtures and their use in the treatment and/or prevention of infections, and in particular, for reducing the severity of childhood infection or in the treatment and/or prevention of childhood infection.
    Type: Application
    Filed: January 13, 2012
    Publication date: May 17, 2012
    Applicant: N.V. Nutricia
    Inventors: Belinda POTAPPEL-VAN 'T LAND, Johan GARSSEN, Gunther BOEHM, Bernd STAHL
  • Patent number: 8114441
    Abstract: A nutritional or pharmaceutical composition containing a fat component, a protein component and a carbohydrate component and comprising whey and casein. The composition has a weight ratio of casein to whey is 1:1 to 1:2.4 and that the composition contains: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids. The long chain polyunsaturated fatty acid being docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and f) 2 to 12 grams indigestible oligosaccharides having a degree of polymerization of 2 to 100 per 100 gram dry weight of the composition. The composition reduces—among others—the risks attached to feeding whey dominant infant formula.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: February 14, 2012
    Assignee: N.V. Nutricia
    Inventors: Günther Boehm, Christopher Beermann, Bernd Stahl, Laura M'rabet, Johan Garssen
  • Publication number: 20120027885
    Abstract: The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and to a corresponding composition. Said composition comprises a n-3 polyunsaturated fatty acid fraction containing at least 0.1 wt % docosahexaenoic acid (DHA) based on total weight of the lipid, at least 0.01 wt % n-3 docosapentaenoic acid (DPAn-3) based on total weight of the lipid, and at least 0.01 wt. % eicosapentaenoic acid (EPA) based on total weight of the lipid, wherein the sum of DHA, DPAn-3 and EPA is below 1 wt. % of total lipid.
    Type: Application
    Filed: October 3, 2011
    Publication date: February 2, 2012
    Applicant: N.V. NUTRICIA
    Inventors: Bernd STAHL, Günther BOEHM, Christopher BEERMANN, Johan GARSSEN
  • Patent number: 8053471
    Abstract: The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and to a corresponding composition. Said composition comprises a n-3 polyunsaturated fatty acid fraction containing at least 0.1 wt docosahexaenoic acid (DHA) based on total weight of the lipid, at least 0.01 wt % n-3 docosapentaenoic acid (DPAn-3) based on total weight of the lipid, and at least 0.01 wt. % eicosapentaenoic acid (EPA) based on total weight of the lipid, wherein the sum of DHA, DPAn-3 and EPA is below 1 wt. % of total lipid.
    Type: Grant
    Filed: November 11, 2005
    Date of Patent: November 8, 2011
    Assignee: N.V. Nutricia
    Inventors: Bernd Stahl, Günther Boehm, Christopher Beermann, Johan Garssen
  • Publication number: 20110182934
    Abstract: Disclosed is a nutritional composition comprising a combination of non-digestible oligosaccharides and a product obtained by incubating an aqueous substrate by bifidobacteria and optionally a product obtained by incubating an aqueous substrate by S. thermophilus. Said combination synergistically improves the immune system by stimulating the Th1 response, and/or decreasing the Th2 response, improving the vaccination response, improving the resistance against infections and/or decreasing allergy.
    Type: Application
    Filed: June 12, 2009
    Publication date: July 28, 2011
    Inventors: Belinda Potappel-van 'T Land, Leon Matthieu Johannes Knippels, Alma Jildou Nauta, Johan Garssen