Patents by Inventor Johan Kajanus

Johan Kajanus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CERTAIN 3-AZABICYCLO[3.1.0]HEXANES AS GLP-1 RECEPTOR MODULATORS
    Publication number: 20250066338
    Abstract: There are disclosed certain 3-azabicyclo[3.1.0]hexanes, and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are GLP-1 receptor modulators and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disease and metabolic conditions, for example Type 2 diabetes.
    Type: Application
    Filed: December 15, 2022
    Publication date: February 27, 2025
    Inventors: Magnus POLLA, Joakim BERGMAN, Johan SUNDELL, Jonas BRÅNALT, Johan KAJANUS, Ekaterina RATKOVA, Magnus JOHANSSON
  • CERTAIN 3-AZABICYCLO[3.1.0]HEXANES AS GLP-1 RECEPTOR MODULATORS
    Publication number: 20250042882
    Abstract: There are disclosed certain 3-azabicyclo[3.1.0]hexanes, and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are GLP-1 receptor modulators and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disease and metabolic conditions, for example Type 2 diabetes.
    Type: Application
    Filed: December 15, 2022
    Publication date: February 6, 2025
    Inventors: Magnus POLLA, Joakim BERGMAN, Johan SUNDELL, Jonas BRÅNALT, Johan KAJANUS, Ekaterina RATKOVA, Magnus JOHANSSON
  • CERTAIN 2,5-DIAZABICYCLO[4.2.0]OCTANES AS GLP-1 RECEPTOR MODULATORS
    Publication number: 20240417393
    Abstract: There are disclosed certain 2,5-diazabicyclo[4.2.0]octanes of formula (I), and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are GLP-1 receptor modulators and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disease and metabolic conditions, for example Type 2 diabetes.
    Type: Application
    Filed: October 4, 2022
    Publication date: December 19, 2024
    Inventors: Magnus POLLA, Joakim BERGMAN, Johan SUNDELL, Jonas BRÅNALT, Ekaterina RATKOVA, Johan KAJANUS, Magnus JOHANSSON
  • Benzoxazinone amides as mineralocorticoid receptor modulators
    Patent number: 10017502
    Abstract: Disclosed are certain derivatives of benzoxazinone amides of formula (I), or pharmaceutically acceptable salts thereof, (Formula (I)) that act as mineralocorticoid (MR) receptor modulators that may reduce oxidative stress in endothelium and hence improve vascular function, to methods for their potential therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: July 10, 2018
    Assignee: AstraZeneca AB
    Inventors: Gavin O'Mahony, Michael Kossenjans, Karl Edman, Johan Kajanus, Carl Anders Hogner, Philip Cornwall, Andrew Turner
  • BENZOXAZINONE AMIDES AS MINERALOCORTICOID RECEPTOR MODULATORS
    Publication number: 20170217945
    Abstract: Disclosed are certain derivatives of benzoxazinone amides of formula (I), or pharmaceutically acceptable salts thereof, (Formula (I)) that act as mineralocorticoid (MR) receptor modulators that may reduce oxidative stress in endothelium and hence improve vascular function, to methods for their potential therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.
    Type: Application
    Filed: June 26, 2015
    Publication date: August 3, 2017
    Applicant: AstraZeneca AB
    Inventors: Gavin O'Mahony, Michael Kossenjans, Karl Edman, Johan Kajanus, Carl Anders Hogner, Philip Cornwall, Andrew Turner
  • Benzoxazinone amides as mineralocorticoid receptor modulators
    Patent number: 9394291
    Abstract: Disclosed are certain derivatives of benzoxazinone amides of formula (I), or pharmaceutically acceptable salts thereof, that act as mineralocorticoid (MR) receptor modulators that may reduce oxidative stress in endothelium and hence improve vascular function, to methods for their potential therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: July 19, 2016
    Assignee: AstraZeneca AB
    Inventors: Gavin O'Mahony, Michael Kossenjans, Karl Edman, Johan Kajanus, Karl Anders Hogner, Philip Cornwall, Andrew Turner
  • BENZOXAZINONE AMIDES AS MINERALOCORTICOID RECEPTOR MODULATORS
    Publication number: 20150376170
    Abstract: Disclosed are certain derivatives of benzoxazinone amides of formula (I), or pharmaceutically acceptable salts thereof, that act as mineralocorticoid (MR) receptor modulators that may reduce oxidative stress in endothelium and hence improve vascular function, to methods for their potential therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.
    Type: Application
    Filed: June 29, 2015
    Publication date: December 31, 2015
    Applicant: ASTRAZENECA AB
    Inventors: Gavin O'MAHONY, Michael KOSSENJANS, Karl EDMAN, Johan KAJANUS, Karl Anders HOGNER, Philip CORNWALL, Andrew TURNER
  • Oxabispidine compounds for the treatment of cardiac arrhythmias
    Patent number: 7928225
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R41 to R46, X, Y and Z have meanings given in the description, which compounds are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: April 19, 2011
    Assignee: AstraZeneca AB
    Inventors: Annika Björe, David Cladingboel, Gareth Ensor, Adam Herring, Johan Kajanus, Robert Lundqvist, Christina Olsson, Carl-Gustav Sigfridsson, Gert Strandlund
  • Isoindoline Derivatives For The Treatment Of Arrhythmias
    Publication number: 20100298392
    Abstract: There is provided compounds of formula I, wherein R1 to R7 have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Application
    Filed: July 12, 2007
    Publication date: November 25, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Annika Bjore, Jonas Bostrom, Ojvind Davidsson, Hans Emtenas, Ulrik Gran, Tommy Iliefski, Johan Kajanus, Roine Olsson, Lars Sandberg, Gert Strandlund, Johan Sundell, Zhong-Qing Yuan
  • Oxabispidine compounds and their use in the treatment of cardiac arrhythmias
    Patent number: 7648985
    Abstract: There is provided compounds of formula (I), wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: June 13, 2005
    Date of Patent: January 19, 2010
    Assignee: AstraZeneca AB
    Inventors: Annika Bjore, Ulrik Gran, Peter Bonn, Johan Kajanus, Christina Olsson, Fritiof Ponten
  • Novel Oxabispidine Compounds And Their Use In The Treatment Of Cardiac Arrhythmias
    Publication number: 20090270383
    Abstract: There is provided compounds of formula (I), wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Application
    Filed: July 6, 2009
    Publication date: October 29, 2009
    Applicant: AstraZeneca AB
    Inventors: Annika Bjore, Peter Bonn, Ulrik Gran, Johan Kajanus, Christina Olsson, Fritiof Ponten
  • New Oxabispidine Compounds For The Treatment Of Cardiac Arrhythmias
    Publication number: 20090054422
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R41 to R46, X, Y and Z have meanings given in the description, which compounds are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Application
    Filed: June 12, 2006
    Publication date: February 26, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Annika Bjore, David Cladingboel, Gareth Ensor, Adam Herring, Johan Kajanus, Robert Lundqvist, Christina Olsson, Carl-Gustav Sigfridsson, Gert Strandlund
  • Novel Oxabispidine Compounds and Their Use in the Treatment of Cardiac Arrhythmias
    Publication number: 20090005558
    Abstract: There is provided compounds of formula (I), wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Application
    Filed: June 13, 2005
    Publication date: January 1, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Annika Bjore, Peter Bonn, Ulrik Gran, Johan Kajanus, Christina Olsson, Fritiof Ponten
  • NEW COMPOUNDS I/418
    Publication number: 20080015237
    Abstract: There is provided compounds of formula I, wherein R1 to R7 have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Application
    Filed: July 11, 2007
    Publication date: January 17, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Annika Bjore, Jonas Bostrom, Ojvind Davidsson, Hans Emtenas, Ulrik Gran, Tommy Iliefski, Johan Kajanus, Roine Olsson, Gert Strandlund, Johan Sundell, Zhong-Qing Yuan, Lars Sandberg