Patents by Inventor Johan P. M. Sanders

Johan P. M. Sanders has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transformed industrial bacillus strains and methods for making and using them
    Patent number: 5624829
    Abstract: Novel methods and novel industrial unicellular microorganism strains, particularly industrial Bacillus strains, are provided for enhanced production of endogenous and exogenous polypeptides. Cloning vehicles containing the gene expressing the polypeptide of interest are introduced into a compatible host. Transformed hosts harboring the introduced vehicle in a stable way by integration of the vehicle into the host cells chromosome are selected. Efficient transfer of the vehicle containing the gene of interest is achieved with the resulting industrial strain transformants being effective, stable producers of the desired polypeptide product.
    Type: Grant
    Filed: December 21, 1992
    Date of Patent: April 29, 1997
    Assignee: Gist-Brocades, B.V.
    Inventors: Johan P. M. Sanders, Johannes A. van den Berg, Peter M. Andreoli, Yvonne J. Vos, Jan H. van Ee, Leo J. S. M. Mulleners
  • Molecular cloning and expression in industrial Bacillus species
    Patent number: 5238833
    Abstract: Novel methods and novel industrial unicellular microorganism strains, particularly industrial Bacillus strains, are provided for enhanced production of endogenous and exogenous polypeptides. Cloning vehicles containing the gene expressing the polypeptide of interest are introduced into a compatible host. Transformed hosts harboring the introduced vehicle in a stable way by integration of the vehicle into the host cells chromosome are selected Efficient transfer of the vehicle containing the gene of interest is achieved, with the resulting industrial strain transformants being effective, stable producers of the desired polypeptide product.
    Type: Grant
    Filed: May 13, 1991
    Date of Patent: August 24, 1993
    Assignee: Gist-brocades, NV
    Inventors: Johan P. M. Sanders, Johannes A. Van Den Berg, Peter M. Andreoli, Yvonne J. Vos, Jan H. Van EE, Leo J. S. M. Mulleners
  • Process for the preparation of oligosaccharides-containing products from biomass
    Patent number: 4677198
    Abstract: Process for the preparation of oligosaccharides-containing products from biomass involving the use of hydrochloric acid for partly hydrolyzing biomass to easily fermentable oligosaccharides-containing products and easy recovery of the hydrochloric acid and the oligosaccharides containing products. The oligosaccharides-containing products themselves and use of the latter for the preparation of useful products like ethanol and penicillin by fermentation.
    Type: Grant
    Filed: November 15, 1984
    Date of Patent: June 30, 1987
    Assignee: Gist-Brocades N.V.
    Inventors: Paul E. Linnett, Johan P. M. Sanders
  • Plasmid and its use
    Patent number: 4460688
    Abstract: Plasmid conferring resistance to streptomycin (Sm.sup.R) and neomycin (Neo.sup.R) upon its host (e.g. a Bacillus, Staphylococcus or Escherichia coli) and which after having taken up a foreign DNA fragment at one of its restriction sites with loss of its Sm.sup.R or Neo.sup.R phenotype, is still capable of replicating and expressing genetic information in its host.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: July 17, 1984
    Assignee: Gist Brocades NV
    Inventors: Johan P. M. Sanders, Andrew J. P. Docherty
  • Plasmid and its use
    Patent number: 4430434
    Abstract: Plasmid conferring resistance to streptomycin (Sm.sup.R) and neomycin (Neo.sup.R) upon its host (e.g. a Bacillus, Staphylococcus or Escherichia coli) and which after having taken up a foreign DNA fragment at one of its restriction sites with loss of its Sm.sup.R or Neo.sup.R phenotype, is still capable of replicating and expressing genetic information in its host.
    Type: Grant
    Filed: May 7, 1980
    Date of Patent: February 7, 1984
    Assignee: Gist Brocades NV
    Inventors: Johan P. M. Sanders, Andrew J. P. Docherty