Abstract: The present invention stems from the finding that two genes designated R2R1 and R2R2, play important roles in tissue development and cancer biology. In particular, the inventors have discovered that these two genes are expressed in pulmonary cells and are required for late branching morphogenesis of pulmonary epithelium and endothelium and support the development/maintenance of the refined three dimensional architecture of the lung. These genes are essential in the squamous differentiation program and development/maintenance of the progenitor (Krt14 expressing) cell pool. Moreover, the inventors have identified crucial roles for these genes in cancer biology, particularly processes associated with the acquisition of an immortal and metastatic phenotype (including cancer progression and metastasis) and pulmonary and cardiac development. Accordingly, the invention provides compounds and methods for use in the treatment of cardiac and pulmonary diseases and well as in cancer.

Abstract: In a Distributed Node Concensus Protocol (DNCP) network, a first device publishes node data comprising data, a data identifier and a sequence number, provides the node data to requesting devices in the DNCP network, receives acknowledgements of reception of the node data from the requesting devices, each acknowledgement comprising the data identifier and the sequence number of the node data, and, for the node data, finds the smallest sequence number among the received acknowledgements and determines that the node data has propagated through the network in case the smallest sequence number is at least equal to the sequence number of the node data. Upon determination that the data has propagated the network, the first device can perform an action that requires the data to have propagated through the network.

Abstract: The present invention stems from the finding that two genes designated R2R1 and R2R2, play important roles in tissue development and cancer biology. In particular, the inventors have discovered that these two genes are expressed in pulmonary cells and are required for late branching morphogenesis of pulmonary epithelium and endothelium and support the development/maintenance of the refined three dimensional architecture of the lung. These genes are essential in the squamous differentiation program and development/maintenance of the progenitor (Krt14 expressing) cell pool. Moreover, the inventors have identified crucial roles for these genes in cancer biology, particularly processes associated with the acquisition of an immortal and metastatic phenotype (including cancer progression and metastasis) and pulmonary and cardiac development. Accordingly, the invention provides compounds and methods for use in the treatment of cardiac and pulmonary diseases and well as in cancer.

Abstract: A file creation method comprising: creating file content at a particular location and time using a portable device; and obtaining data from wireless communication devices detectable by the portable device at the particular location and time thereby to obtain a set of data. The set of data identifies or enables identification of the wireless communication devices. The method further comprises associating the set of data and time with the file content to enable subsequent analysis to determine the particular location using a time-dependent database.

Abstract: The present invention stems from the finding that two genes designated R2R1 and R2R2, play important roles in tissue development and cancer biology. In particular, the inventors have discovered that these two genes are expressed in pulmonary cells and are required for late branching morphogenesis of pulmonary epithelium and endothelium and support the development/maintenance of the refined three dimensional architecture of the lung. These genes are essential in the squamous differentiation program and development/maintenance of the progenitor (Krt14 expressing) cell pool. Moreover, the inventors have identified crucial roles for these genes in cancer biology, particularly processes associated with the acquisition of an immortal and metastatic phenotype (including cancer progression and metastasis) and pulmonary and cardiac development. Accordingly, the invention provides compounds and methods for use in the treatment of cardiac and pulmonary diseases and well as in cancer.

Abstract: EPG data regarding programs and their scheduled times are structured and/or transmitted in such a way that program and schedule records are interleaved. This scheme allows better handling by receiving devices such as embedded devices (i.e. LCD remote controls), because a more efficient reception and storage of transmitted data is possible. In particular, the receiving device can read, parse and store the downloaded EPG data on the fly as it is being received (it can start reading, parsing and storing before the complete reception of data id finished). At any time when the device would have to stop storing EPG data into persistent storage, (almost) all of the data that was stored can actually be used.

Abstract: A method of acquiring a received spread spectrum signal comprises receiving a spread spectrum signal, analyzing the received signal to detect interference within the received signal, and adapting the baseband processing of the received signal to reduce power consumption during periods of detected interference. This allows the GPS processing resources to be focussed on areas of signal where there is little or no interference, and this is possible without modification to the source of interference. The interference is detected from an analysis of the received signal, and in particular before the baseband digital signal processing.

Abstract: A method of creating an image file and a digital camera for the same. The method comprised the steps of: (i) generating and storing image data corresponding to a photo or video clip; (ii) sampling received GPS signals and storing the resultant GPS signal samples (hereafter “raw GPS data”); and (iii) creating a single file containing both the image data and the raw GPS data.

Abstract: A camera includes a satellite positioning system. The camera comprises a camera lens (32) having a focal axis (36), a satellite receiver for receiving data samples of satellite broadcast and a satellite system antenna (38). The satellite system antenna (38) has a gain in the direction of the lens axis which is greater than the gain in all directions perpendicular to the lens axis.

Abstract: A file creation method comprising:creating file content at a particular location and time using a portable device; and obtaining data from wireless communication devices detectable by the portable device at the particular location and time thereby to obtain a set of data. The set of data identifies or enables identification of the wireless communication devices. The method further comprises associating the set of data and time with the file content to enable subsequent analysis to determine the particular location using a time-dependent database.

Abstract: A method of processing signals from a satellite positioning system. The method comprises using a processing method dependent on one or more parameters of a first trigger signal in addition to its timing. The processing method may comprise controlling how data is captured and stored and/or how data is subsequently processed.

Abstract: A camera includes a satellite positioning system. The camera comprises a camera lens (32) having a focal axis (36), a satellite receiver for receiving data samples of satellite broadcast and a satellite system antenna (38). The satellite system antenna (38) has a gain in the direction of the lens axis which is greater than the gain in all directions perpendicular to the lens axis.

Abstract: A method of acquiring a received spread spectrum signal comprises receiving a spread spectrum signal, analysing the received signal to detect interference within the received signal, and adapting the baseband processing of the received signal to reduce power consumption during periods of detected interference. This allows the GPS processing resources to be focussed on areas of signal where there is little or no interference, and this is possible without modification to the source of interference. The interference is detected from an analysis of the received signal, and in particular before the baseband digital signal processing.

Abstract: A method of determining a location of an event of interest by processing signals from a satellite positioning system. The method comprises receiving recorded blocks of data samples of a satellite broadcast including blocks recorded at the approximate location of the event of interest, each block including one or more timestamps generated within a first portable device at which the samples were recorded; receiving a time of occurrence of the event recorded independently of the samples; comparing the timestamps and the time of occurrence to identify at least one block corresponding to the event; and processing the data samples of the identified at least one block to derive position information approximating the location of the event.

Abstract: A method of determining a location of an event of interest by processing signals from a satellite positioning system. The method comprises receiving recorded blocks of data samples of a satellite broadcast including blocks recorded at the approximate location of the event of interest, each block including one or more timestamps generated within a first portable device at which the samples were recorded; receiving a time of occurrence of the event recorded independently of the samples; comparing the timestamps and the time of occurrence to identify at least one block corresponding to the event; and processing the data samples of the identified at least one block to derive position information approximating the location of the event.

Abstract: The present invention relates generally to therapy and diagnosis of depression. In particular this invention relates to the polypeptides as well as to the polynucleotides encoding these polypeptides, wherein said polypeptides are shown to play a central role in mediating the endocrine response to corticotropin releasing hormone. These polypeptides and polynucleotides are useful in the diagnosis, treatment and/or prevention of depression.

Abstract: A method of creating an image file and a digital camera for the same.

Abstract: EPG data regarding programs and their scheduled times are structured and/or transmitted in such a way that program and schedule records are interleaved. This scheme allows better handling by receiving devices such as embedded devices (i.e. LCD remote controls), because a more efficient reception and storage of transmitted data is possible. In particular, the receiving device can read, parse and store the downloaded EPG data on the fly as it is being received (it can start reading, parsing and storing before the complete reception of data id finished). At any time when the device would have to stop storing EPG data into persistent storage, (almost) all of the data that was stored can actually be used.

Abstract: The method is used to provide a software package for installation in a user station (US) without revealing the contents of the software package. The method includes the steps of encoding a readable source version (PACK.SOURCE) of the software package following a predefined encoding algorithm thereby generating an encoded software package (PACK.ENC) and delivering the encoded software package (PACK.ENC) from a provider station (PS) to the user station. In order to install the encoded software package (PACK.ENC) at the user station (US) the method further includes the step of providing, either together with the encoded software package (PACK.ENC) or separately, a basis software package (BASIS) for combined decoding and compiling of the encoded software package (PACK.ENC). The basis software package (BASIS) includes software to perform the combined decoding and compiling thereby generating a compiled software package (PACK.COMP).

Abstract: To allocate a number of data elements to a set of carriers, the carriers are divided into N subsets of carriers according to a predetermined carrier criterion whilst the data elements are classified into N groups of data elements according to a predetermined data criterion, N being an integer greater than one. The predetermined data and carrier criterion have a relation on the basis of which the N subsets of carriers are associated one by one to the N groups of data elements. The data elements classified in such a group are then allowed to be modulated only on carriers which form part of the subset associated with this group. In addition, for each subset of carriers and related group of data elements, the distribution is obtained by means of information from subset dependent `required SNR (Signal to Noise Ratio) per data element`-tables and previously carried out SNR measurements for each carrier.