Abstract: The disclosure relates to a method for producing three-dimensional cell cluster on an inorganic cell culture platform comprising three-dimensional structures, preferably fractal structures. Such three-dimensional structures are useful for culturing cells and tissues, preferably in three dimensions. Such three-dimensional structures are useful for inducing differentiation, preferably of non-embryonic stem cells. In particular, such three-dimensional (3D) structures are useful for culturing primary tissue cells.

Abstract: A hair cutting device includes a hair cutting device body and an interchangeable comb unit for defining a hair length after cutting. The hair cutting device body further includes a comb interface for releasable attachment of the comb unit to the hair cutting device body, and a hair length indicator operatively coupled to the comb interface for indicating the hair length to a user. The interchangeable comb unit includes a comb identification member for identifying a hair length associated with the comb unit, and the comb interface includes a comb recognition arrangement being electrically coupled to the hair length indicator. The comb recognition arrangement is configured to sense the comb identification member when the comb unit is connected to the hair cutting device body, and to provide an electronic signal indicative of the hair length associated with the comb unit to the hair length indicator.

Abstract: A method of manufacturing a plurality of through-holes (132) in a layer of material by subjecting the layer to directional dry etching to provide through-holes (132) in the layer of material; For batch-wise production, the method comprises after a step of providing a layer of first material (220) on base material and before the step of directional dry etching, providing a plurality of holes at the central locations of pits (210), etching base material at the central locations of the pits (210) so as to form a cavity (280) with an aperture (281), depositing a second layer of material (240) on the base material in the cavity (280), and subjecting the second layer of material (240) in the cavity (280) to said step of directional dry etching using the aperture (281) as the opening (141) of a shadow mask.

Abstract: A method of manufacturing a plurality of through-holes (132) in a layer of material by subjecting the layer to directional dry etching to provide through-holes (132) in the layer of material; For batch-wise production, the method comprises after a step of providing a layer of first material (220) on base material and before the step of directional dry etching, providing a plurality of holes at the central locations of pits (210), etching base material at the central locations of the pits (210) so as to form a cavity (280) with an aperture (281), depositing a second layer of material (240) on the base material in the cavity (280), and subjecting the second layer of material (240) in the cavity (280) to said step of directional dry etching using the aperture (281) as the opening (141) of a shadow mask.

Abstract: The present invention provides a microneedle, comprising a shaft of a monocrystalline material having at least three walls which are formed by a crystal plane of the monocrystalline material; and a tip connected to an end of the shaft comprising at least three walls which are formed by a crystal plane of the material. The material is preferably silicon. Two of the walls of the tip are formed by the same crystal planes as two walls of the shaft. These two walls are formed by a <111> crystal plane. Preferably, three walls of the tip are formed by a <111> crystal plane.

Abstract: A hair cutting device includes a hair cutting device body and an interchangeable comb unit for defining a hair length after cutting. The hair cutting device body further includes a comb interface for releasable attachment of the comb unit to the hair cutting device body, and a hair length indicator operatively coupled to the comb interface for indicating the hair length to a user. The interchangeable comb unit includes a comb identification member for identifying a hair length associated with the comb unit, and the comb interface includes a comb recognition arrangement being electrically coupled to the hair length indicator. The comb recognition arrangement is configured to sense the comb identification member when the comb unit is connected to the hair cutting device body, and to provide an electronic signal indicative of the hair length associated with the comb unit to the hair length indicator.

Abstract: The invention relates to a method for making a 3D nanostructure having a nanosubstructure, comprising the steps of: i) providing a mold comprising at least one sharp concave corner; ii) conformational depositing at least one structural material in the sharp concave corner; iii) isotropically removing structural material; iv) depositing at least one other structural material; v) removing earlier deposited structural material; vi) forming a nanosubstructure; and vii) removing the mold thereby providing the 3D nanostructure having the nanosubstructure.

Abstract: A hair cutting device includes a hair cutting device body and an interchangeable comb unit for defining a hair length after cutting. The hair cutting device body further includes a comb interface for releasable attachment of the comb unit to the hair cutting device body, and a hair length indicator operatively coupled to the comb interface for indicating the hair length to a user. The interchangeable comb unit includes a comb identification member for identifying a hair length associated with the comb unit, and the comb interface includes a comb recognition arrangement being electrically coupled to the hair length indicator. The comb recognition arrangement is configured to sense the comb identification member when the comb unit is connected to the hair cutting device body, and to provide an electronic signal indicative of the hair length associated with the comb unit to the hair length indicator.

Abstract: The invention relates to a method for making a 3D nanostructure having a nanosubstructure, comprising the steps of: i) providing a mold comprising at least one sharp concave corner; ii) conformational depositing at least one structural material in the sharp concave corner; iii) isotropically removing structural material; iv) depositing at least one other structural material; v) removing earlier deposited structural material; vi) forming a nanosubstructure; and vii) removing the mold thereby providing the 3D nanostructure having the nanosubstructure.

Abstract: The invention relates to a method for making a 3D nanostructure having a nanosubstructure, comprising the steps of: i) providing a mold comprising at least one sharp concave corner; ii) conformational depositing at least one structural material in the sharp concave corner; iii) isotropically removing structural material; iv) depositing at least one other structural material; v) removing earlier deposited structural material; vi) forming a nanosubstructure; and vii) removing the mold thereby providing the 3D nanostructure having the nanosubstructure.

Abstract: A hair cutting device (1) comprising a hair cutting device body (3); and an interchangeable comb unit (2) for defining a hair length after cutting. The hair cutting device body (3) further comprises a comb interface for releasable attachment of the comb unit (2) to the hair cutting device body (3); a hair length indicator (7) operatively coupled to the comb interface for indicating the hair length to a user. The interchangeable comb unit (2) comprises a comb identification member (11; 13) identifying a hair length associated with the comb unit (2); and the comb interface comprises a comb recognition arrangement (10; 14a-b) being electrically coupled to the hair length indicator (7). The comb recognition arrangement (10; 14a-b) is configured to sense the comb identification member (11; 13) when the comb unit (2) is connected to the hair cutting device body (3), and to provide an electronic signal indicative of the hair length associated with the comb unit (2) to the hair length indicator (7).

Abstract: The present invention provides a microneedle, comprising a shaft of a monocrystalline material having at least three was which are formed by a crystal plane of the monocrystalline material; and a tip connected to an end of the shaft comprising at least three walls which are formed by a crystal plane of the material. The material is preferably silicon. Two of the walls of the tip are formed by the same crystal planes as two walls of the shaft. These two walls are formed by a <111> crystal plane. Preferably, three walls of the tip are formed by a <111> crystal plane.

Abstract: Abstract: The invention relates to a method for making a 3D nanostructure having a nanosubstructure, comprising the steps of: i) providing a mold comprising at least one sharp concave corner; ii) conformational depositing at least one structural material in the sharp concave corner; iii) isotropically removing structural material; iv) depositing at least one other structural material; v) removing earlier deposited structural material; vi) forming a nanosubstructure; and vii) removing the mold thereby providing the 3D nanostructure having the nanosubstructure.