Abstract: One embodiment is a biochip having an array of biosensors for quantitative determination of protein-protein and/or antibody-antigen interactions. The array comprises at least two biosensors formed on a substrate. The biosensors can be used to detect either the same or different analytes. The biosensors may be acoustical transducers operated in the thickness shear mode of vibration, wherein the density, viscosity, and elasticity at the sensor interface can be ascertained. Additionally, a series of fluidic channels are etched to the same depth as the biosensors. The fluidic channels serve to efficiently deliver the sample to the biosensors. One or more biochips can be housed within an enclosure.

Abstract: A medical device introduction system is adapted to be at least partially insertable into an interior body region of a patient. The system includes a medical imager including a body member having a handle, an elongate member extending from the handle, an imaging device carried at a distal portion of the elongate member, and an introducer enclosing the elongate member. A manipulator is configured for imparting displacement of the introducer to form an angled end portion to define a line of sight extending from the angled end portion. The manipulator is further configured for altering the line of sight to increase a viewing angle of the imaging device.

Abstract: A medical device introduction system is adapted to be at least partially insertable into an interior body region of a patient. The system includes a medical imager including a body member having a handle, an elongate member extending from the handle, an imaging device carried at a distal portion of the elongate member, and an introducer enclosing the elongate member. A manipulator is configured for imparting displacement of the introducer to form an angled end portion to define a line of sight extending from the angled end portion. The manipulator is further configured for altering the line of sight to increase a viewing angle of the imaging device.

Abstract: One embodiment is a biochip having an array of biosensors for quantitative determination of protein-protein and/or antibody-antigen interactions. The array comprises at least two biosensors formed on a substrate. The biosensors can be used to detect either the same or different analytes. The biosensors may be acoustical transducers operated in the thickness shear mode of vibration, wherein the density, viscosity, and elasticity at the sensor interface can be ascertained. Additionally, a series of fluidic channels are etched to the same depth as the biosensors. The fluidic channels serve to efficiently deliver the sample to the biosensors. One or more biochips can be housed within an enclosure.