Patents by Inventor Johann Posch
Johann Posch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240100140Abstract: The disclosure provides synthetic (e.g. recombinant) pneumococcal saccharide comprising one or more repeat unit(s) ?4)-?-D-Glcp-(1?3)-[[?-L-Rhap-(1?2)]-[Gro-(2?P?3)]-?-D-Galp-(1?4)]-?-L-Rhap-(1?. Also provided are conjugates comprising a ?4)-?-D-Glcp-(1?3)-[[?-L-Rhap-(1?2)]-[Gro-(2?P?3)]-?-D-Galp-(1?4)]-?-L-Rhap-(1?, immunogenic compositions, vaccines and their use in preventing or treating infection by Streptococcus pneumoniae.Type: ApplicationFiled: April 6, 2023Publication date: March 28, 2024Applicant: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Amirreza FARIDMOAYER, Rainer FOLLADOR, Stefan Jochen KEMMLER, Michael Thomas KOWARIK, Gerd Martin LIPOWSKY, Gerald Johann POSCH, Fabio SERVENTI
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Publication number: 20230293657Abstract: The present invention relates to the field of immunogenic compositions and vaccines, their manufacture, host cells which can be used in their manufacture and the use of such immunogenic compositions and vaccines in medicine. More particularly, it relates to Klebsiella pneumoniae O-antigens, conjugates comprising a K. pneumoniae O-antigen, host cells suitable for their production and immunogenic compositions or vaccines containing at least one Klebsiella pneumoniae O-antigen.Type: ApplicationFiled: June 17, 2021Publication date: September 21, 2023Inventors: Maria Paula CARRANZA SANDMEIER, Rainer FOLLADOR, Veronica Gambillara FONCK, Stefan Jochen KEMMLER, Patricia Martin KILLIAS, Michael Thomas KOWARIK, Gerd Martin LIPOWSKY, Gerald Johann POSCH, Fabio SERVENTI, Dominique Nicolas SIRENA
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Publication number: 20230226175Abstract: The present invention relates to the field of modified proteins, immunogenic compositions and vaccines comprising the modified proteins, their manufacture and the use of such compositions in medicine. More particularly, it relates to a modified EPA (Exotoxin A of Pseudomonas aeruginosa) protein. The modified EPA can be used as a carrier protein for other antigens, particularly saccharide antigens or other antigens lacking T cell epitopes.Type: ApplicationFiled: June 17, 2021Publication date: July 20, 2023Inventors: Stefan Jochen KEMMLER, Christian LIZAK, Gerald Johann POSCH, Julien Laurent QUEBATTE
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Patent number: 11654190Abstract: The disclosure provides synthetic (e.g. recombinant) pneumococcal saccharide comprising one or more repeat unit(s) ?4)-?-D-Glcp-(1?3)-[[?-L-Rhap-(1?2)]-[Gro-(2?P?3)]-?-D-Galp-(1?4)]-?-L-Rhap-(1?. Also provided are conjugates comprising a ?4)-?-D-Glcp-(1?3)-[[?-L-Rhap-(1?2)]-[Gro-(2?P?3)]-?-D-Galp-(1?4)]-?-L-Rhap-(1?, immunogenic compositions, vaccines and their use in preventing or treating infection by Streptococcus pneumoniae.Type: GrantFiled: July 17, 2018Date of Patent: May 23, 2023Assignee: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Amirreza Faridmoayer, Rainer Follador, Stefan Jochen Kemmler, Michael Thomas Kowarik, Gerd Martin Lipowsky, Gerald Johann Posch, Fabio Serventi
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Publication number: 20230060184Abstract: The disclosure provides synthetic (e.g. recombinant) pneumococcal saccharides comprising one or more repeat unit(s) ?4)-?-D-Glcp-(1?4)-[Gro-(2?P?3)]-?-D-Galp-(1?4)-?-L-Rhap-(1?. Also provided are conjugates comprising a ?4)-?-D-Glcp-(1?4)-[Gro-(2?P?3)]-?-D-Galp-(1?4)-?-L-Rhap-(1?, immunogenic compositions, vaccines and their use in preventing or treating infection by Streptococcus pneumoniae.Type: ApplicationFiled: May 31, 2022Publication date: March 2, 2023Applicant: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Amirreza FARIDMOAYER, Rainer FOLLADOR, Stefan Jochen KEMMLER, Michael Thomas KOWARIK, Gerald Johann POSCH, Fabio SERVENTI
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Patent number: 11376314Abstract: The disclosure provides synthetic (e.g. recombinant) pneumococcal saccharides comprising one or more repeat unit(s) ?4)-?-D-Glcp-(1?4)-[Gro-(2?P?3)]-?-D-Galp-(1?4)-?-L-Rhap-(1?. Also provided are conjugates comprising a ?4)-?-D-Glcp-(1?4)-[Gro-(2?P?3)]-?-D-Galp-(1?4)-?-L-Rhap-(1?, immunogenic compositions, vaccines and their use in preventing or treating infection by Streptococcus pneumoniae.Type: GrantFiled: July 17, 2018Date of Patent: July 5, 2022Inventors: Amirreza Faridmoayer, Rainer Follador, Stefan Jochen Kemmler, Michael Thomas Kowarik, Gerald Johann Posch, Fabio Serventi
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Publication number: 20220054632Abstract: Carrier proteins modified to incorporate one or more pilin glycotags and applications thereof for O-linked glycosylation are provided. In particular, a modified carrier protein comprising a carrier protein that comprises at least one GlycoTag, wherein the at least one GlycoTag is a Neisseria gonorrhoeae PglL GlycoTag (NgGlycoTag), Neisseria lactamica PglL GlycoTag (NlGlycoTag), or Neisseria shayeganii GlycoTag (NsGlycoTag), or combinations thereof is provided, together with nucleic acids and vectors encoding the modified carrier protein, host cells comprising these modofoed carrier proteins or nucleic acids encoding them, bioconjugates, methods of making bioconjugates and uses of the bioconjugates.Type: ApplicationFiled: December 11, 2019Publication date: February 24, 2022Applicant: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Rainer FOLLADOR, Stefan Jochen KEMMLER, Michael Thomas KOWARIK, Gerald Johann POSCH
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Publication number: 20200188502Abstract: The disclosure provides synthetic (e.g. recombinant) pneumococcal saccharides comprising one or more repeat unit(s) ?4)-?-D-Glcp-(1?4)-[Gro-(2?P?3)]-?-D-Galp-(1?4)-?-L-Rhap-(1?. Also provided are conjugates comprising a ?4)-?-D-Glcp-(1?4)-[Gro-(2?P?3)]-?-D-Galp-(1?4)-?-L-Rhap-(1?, immunogenic compositions, vaccines and their use in preventing or treating infection by Streptococcus pneumoniae.Type: ApplicationFiled: July 17, 2018Publication date: June 18, 2020Applicant: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Amirreza FARIDMOAYER, Rainer FOLLADOR, Stefan Jochen KEMMLER, Michael Thomas KOWARIK, Gerald Johann POSCH, Fabio SERVENTI
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Publication number: 20200179505Abstract: The disclosure provides synthetic (e.g. recombinant) pneumococcal saccharide comprising one or more repeat unit(s)?4)-?-D-Glcp-(1?3)-[[?-L-Rhap-(1?2)]-[Gro-(2?P?3)]-?-D-Galp-(1?4)]-?-L-Rhap-(1?.Also provided are conjugates comprising a ?4)-?-D-Glcp-(1?3)-[[?-L-Rhap-(1?2)]-[Gro-(2?P?3)]-?-D-Galp-(1?4)]-?-L-Rhap-(1?, immunogenic compositions, vaccines and their use in preventing or treating infection by Streptococcus pneumoniae.Type: ApplicationFiled: July 17, 2018Publication date: June 11, 2020Applicant: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Amirreza FARIDMOAYER, Rainer FOLLADOR, Stefan Jochen KEMMLER, Michael Thomas KOWARIK, Gerd Martin LIPOWSKY, Gerald Johann POSCH, Fabio SERVENTI
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Patent number: 6658490Abstract: The present invention provides a method and system for multi-threaded processing that is an improvement over conventional systems. The system of the present invention comprises multiple threads of execution, multiple apartments, shared data, and a concurrency management component. The threads of execution run independently and each occupy one apartment. The apartments contain objects that have methods to perform operations. The shared data contains data that is accessible by all threads within the process. The concurrency management mechanism performs processing so that the multiple threads can execute concurrently in a reliable and robust manner. In an alternative system of the present invention, the threads are separate from the apartments and the threads execute within the apartments to perform processing. After performing the processing, the thread exits the apartment so that the apartment may be occupied by another thread.Type: GrantFiled: June 8, 1999Date of Patent: December 2, 2003Assignee: Microsoft CorporationInventors: Antonty S. Williams, Alexander A. Mitchell, Robert G. Atkinson, C. Douglas Hodges, Johann Posch, Craig H Wittenberg
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Patent number: 6401099Abstract: An object-oriented framework unifies retrieval and browsing of data locally and from remote computer networks. The framework includes a class of monikers that operate on behalf of a client program to asynchronously bind or retrieve data referenced by a name without blocking execution of the client. This allows the client to provide responsive user interaction including when remotely retrieving data.Type: GrantFiled: December 6, 1996Date of Patent: June 4, 2002Assignee: Microsoft CorporationInventors: Srinivasa R. Koppolu, Johann Posch, Victor Stone, Antony S. Williams
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Patent number: 6182108Abstract: The present invention provides a method and system for multi-threaded processing that is an improvement over conventional systems. The system of the present invention comprises multiple threads of execution, multiple apartments, shared data, and a concurrency management component. The threads of execution run independently and each occupy one apartment. The apartments contain objects that have methods to perform operations. The shared data contains data that is accessible by all threads within the process. The concurrency management mechanism performs processing so that the multiple threads can execute concurrently in a reliable and robust manner. In an alternative system of the present invention, the threads are separate from the apartments and the threads execute within the apartments to perform processing. After performing the processing, the thread exits the apartment so that the apartment may be occupied by another thread.Type: GrantFiled: January 31, 1995Date of Patent: January 30, 2001Assignee: Microsoft CorporationInventors: Antonty S. Williams, Alexander A. Mitchell, Robert G. Atkinson, C. Douglas Hodges, Johann Posch, Craig H. Wittenberg
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Patent number: 5675796Abstract: An improved mechanism for communicating between computer programs is provided. In a preferred embodiment of the present invention, a computer system has a source computer program, a destination computer program and a communication mechanism for sending a communication from the source computer program to the destination computer program. The communication mechanism contains a concurrency management mechanism for handling events when a communication is pending. The source computer program sends a communication to the destination computer program using the communication mechanism. While the remote communication is pending, the concurrency management mechanism of the preferred embodiment provides concurrency management. The source computer program then receives a reply to the communication from the destination computer program.Type: GrantFiled: August 16, 1996Date of Patent: October 7, 1997Assignee: Microsoft CorporationInventors: Clark Douglas Hodges, Antony S. Williams, Johann Posch