Patents by Inventor Johanna Bobrow

Johanna Bobrow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210062128
    Abstract: An in vitro tissue plate may include a well plate, a fluidic plate disposed on a bottom surface of the well plate, and a media manifold disposed on a bottom surface of the fluidic plate. The well plate may have at least two wells, including a tissue well and a waste well. The fluid plate may include a fluid channel extending between and fluidly connecting the tissue well to the waste well. The media manifold may include a one or more media outlets fluidly connected to the fluid channel. A tissue layer may be deposited in the tissue well. The tissue layer may include human cells such as neurovascular cells.
    Type: Application
    Filed: June 26, 2020
    Publication date: March 4, 2021
    Applicant: Massachusetts Institute of Technology
    Inventors: Johanna Bobrow, Todd Thorsen, David Walsh, Christina Zook
  • Patent number: 8062846
    Abstract: An apparatus for preparing a nucleic acid component of a sample for amplification includes a porous support having an agent that deactivates a nucleic acid amplification inhibitor component of the sample. The apparatus further includes a housing with an opening and defining an interior. The interior of the housing is in fluid communication with the porous support, and at least a portion of a fluid directed through the opening is directed through at least a portion of the porous support. The apparatus also includes a magnetic substrate for separating nucleic acid from a sample.
    Type: Grant
    Filed: May 18, 2007
    Date of Patent: November 22, 2011
    Assignees: Massachusetts Institute of Technology, Smiths Detection-Edgewood, Inc.
    Inventors: Laura T. Bortolin, Lalitha Parameswaran, James Harper, Johanna Bobrow, Mark A. Hollis, Drew Chapman Brown, Eric Scott Clasen, John Calvin Schmidt
  • Publication number: 20080131949
    Abstract: A method for preparing a nucleic acid component of a sample for amplification includes contacting the sample with a porous support that deactivates a nucleic acid amplification inhibitor component of the sample and directing a fluid through the porous support, whereby the nucleic acid component of the sample is directed through at least a portion of the porous support and is separated from the support, thereby preparing the nucleic acid component for amplification. The sample is separated from raw sample components through means that include a magnetic substrate. An apparatus suitable for conducting the method of the invention also is described.
    Type: Application
    Filed: May 18, 2007
    Publication date: June 5, 2008
    Inventors: Laura T. Bortolin, Lalitha Parameswaran, James Harper, Johanna Bobrow, Mark A. Hollis, Drew Chapman Brown, Eric Scott Clasen, John Calvin Schmidt
  • Patent number: 7217513
    Abstract: A method for preparing a nucleic acid component of a sample for amplification includes contacting the sample with a porous support that deactivates a nucleic acid amplification inhibitor component of the sample and directing a fluid through the porous support, whereby the nucleic acid component of the sample is directed through at least a portion of the porous support and is separated from the support, thereby preparing the nucleic acid component for amplification.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: May 15, 2007
    Assignee: Massachusetts Institute of Technology
    Inventors: Lalitha Parameswaran, Albert Young, Laura T. Bortolin, Mark A. Hollis, James Harper, Johanna Bobrow
  • Publication number: 20040126783
    Abstract: A method for preparing a nucleic acid component of a sample for amplification includes contacting the sample with a porous support that deactivates a nucleic acid amplification inhibitor component of the sample and directing a fluid through the porous support, whereby the nucleic acid component of the sample is directed through at least a portion of the porous support and is separated from the support, thereby preparing the nucleic acid component for amplification. The sample is separated from raw sample components through means that include a magnetic substrate. An apparatus suitable for conducting the method of the invention also is described.
    Type: Application
    Filed: July 10, 2003
    Publication date: July 1, 2004
    Applicants: Massachusetts Institute of Technology, Smiths Detection-Edgewood, Inc.,
    Inventors: Laura T. Bortolin, Lalitha Parameswaran, James Harper, Johanna Bobrow, Mark A. Hollis, Drew Chapman Brown, Eric Scott Clasen, John Calvin Schmidt
  • Publication number: 20030129614
    Abstract: A method for preparing a nucleic acid component of a sample for amplification includes contacting the sample with a porous support that deactivates a nucleic acid amplification inhibitor component of the sample and directing a fluid through the porous support, whereby the nucleic acid component of the sample is directed through at least a portion of the porous support and is separated from the support, thereby preparing the nucleic acid component for amplification.
    Type: Application
    Filed: July 10, 2002
    Publication date: July 10, 2003
    Applicant: Massachusetts Institute of Technology
    Inventors: Lalitha Parameswaran, Albert Young, Laura T. Bortolin, Mark A. Hollis, James Harper, Johanna Bobrow