Patents by Inventor Johanna MAYERHOFER

Johanna MAYERHOFER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FULL LENGTH KINASE ACTIVITY-CONFORMATION REPORTER
    Publication number: 20220137060
    Abstract: The present invention provides a reporter for a protein fragment complementation assay characterized in that the reporter is a fused protein comprising a first fragment, a second fragment and a protein kinase sequence section, wherein the first fragment and the second fragment are derived from different sections of the same split protein, and wherein the protein kinase sequence section intervenes between the first fragment and the second fragment and wherein the kinase sequence section comprises a kinase domain sequence and one or more regulatory sequence(s). Further the invention provides polynucleotides and cells encoding for the reporter as well as methods of conducting a protein fragment complementation assay with the reporter according to the invention.
    Type: Application
    Filed: December 20, 2021
    Publication date: May 5, 2022
    Inventors: Eduard STEFAN, Johanna MAYERHOFER
  • Full length kinase activity-conformation reporter
    Patent number: 11237173
    Abstract: The present invention provides a reporter for a protein fragment complementation assay characterized in that the reporter is a fused protein comprising a first fragment, a second fragment and a protein kinase sequence section, wherein the first fragment and the second fragment are derived from different sections of the same split protein, and wherein the protein kinase sequence section intervenes between the first fragment and the second fragment and wherein the kinase sequence section comprises a kinase domain sequence and one or more regulatory sequence(s). Further the invention provides polynucleotides and cells encoding for the reporter as well as methods of conducting a protein fragment complementation assay with the reporter according to the invention.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: February 1, 2022
    Assignee: UNIVERSITAT INNSBRUCK
    Inventors: Eduard Stefan, Johanna Mayerhofer
  • FULL LENGTH KINASE ACTIVITY-CONFORMATION REPORTER
    Publication number: 20200033355
    Abstract: The present invention provides a reporter for a protein fragment complementation assay characterized in that the reporter is a fused protein comprising a first fragment, a second fragment and a protein kinase sequence section, wherein the first fragment and the second fragment are derived from different sections of the same split protein, and wherein the protein kinase sequence section intervenes between the first fragment and the second fragment and wherein the kinase sequence section comprises a kinase domain sequence and one or more regulatory sequence(s). Further the invention provides polynucleotides and cells encoding for the reporter as well as methods of conducting a protein fragment complementation assay with the reporter according to the invention.
    Type: Application
    Filed: September 29, 2017
    Publication date: January 30, 2020
    Inventors: Eduard STEFAN, Johanna MAYERHOFER