Patents by Inventor Johanna R. Cruceta

Johanna R. Cruceta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Device and method for monitoring leukocyte migration
    Patent number: 7326563
    Abstract: A device for monitoring leukocyte migration is provided. The device generally includes a plurality of chambers, each chamber including a channel in which leukocyte migration mediators or endothelial cells are disposed therein. The device is fabricated in the footprint of a standard microtiter plate. The invention also provides a method of using the device to monitor leukocyte migration in the presence of physiological shear flow and therefore simulate physiological conditions of a blood vessel in vivo. The invention further provides a method of using the device to high-throughput screen a plurality of test agents.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: February 5, 2008
    Assignee: Surface Logix, Inc.
    Inventors: Enoch Kim, Johanna R. Cruceta
  • Device and method for monitoring leukocyte migration
    Publication number: 20030017582
    Abstract: A device for monitoring leukocyte migration is provided. The device generally includes a plurality of chambers, each chamber including a channel in which leukocyte migration mediators or endothelial cells are disposed therein. The device is fabricated in the footprint of a standard microtiter plate. The invention also provides a method of using the device to monitor leukocyte migration in the presence of physiological shear flow and therefore simulate physiological conditions of a blood vessel in vivo. The invention further provides a method of using the device to high-throughput screen a plurality of test agents.
    Type: Application
    Filed: September 12, 2002
    Publication date: January 23, 2003
    Inventors: Enoch Kim, Johanna R. Cruceta