Patents by Inventor Johanna Sigl

Johanna Sigl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Means and methods for diagnosing heart failure in a subject
    Patent number: 10393762
    Abstract: The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing heart failure in a subject, a method for identifying whether a subject is in need for a therapy of heart failure or a method for determining whether a heart failure therapy is successful. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: August 27, 2019
    Assignees: METANOMICS GMBH, Ruprecht-Karls-Universitaet Heidelberg
    Inventors: Jens Fuhrmann, Regina Reszka, Juergen Kastler, Kristina Busch, Edgar Leibold, Hugo Katus, Norbert Frey, Johanna Sigl, Tanja Weis
  • Means and Methods for Determining a Clearance Normalized Amount of a Metabolite Disease Biomarker in a Sample
    Publication number: 20160047829
    Abstract: The present invention relates to a method for determining a clearance normalized amount of a metabolite disease biomarker in a sample including the steps of (a) determining the amount of the disease biomarker in at least a first type of sample of a subject suspected to suffer from the disease, (b) determining the amount of a kidney function biomarker which correlates with the glomerular filtration rate (GFR) in the said at least first type of sample, and (c) determining a clearance normalized amount for the metabolite disease biomarker by normalizing the amount determined for the metabolite disease biomarker in step (a) to the amount of the kidney function biomarker determined in step (b). Moreover, the invention also relates to a method for diagnosing a disease in a subject suspected to suffer therefrom and to a device for determining a clearance normalized amount of a metabolite disease biomarker in a sample.
    Type: Application
    Filed: October 16, 2013
    Publication date: February 18, 2016
    Applicants: Ruprecht-Karls-Universität Heidelberg, Metanomics GmbH
    Inventors: Jens Fuhrmann, Jenny Fischer, Regina Reszka, Hugo A Katus, Nobert Frey, Johanna Sigl, Tanja Weis