Patents by Inventor JOHANNA TSCHOP

JOHANNA TSCHOP has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for cell expansion
    Patent number: 9845455
    Abstract: The present invention relates to a method for cell expansion. More closely, it relates to a method for expansion of cells, such as mesenchymal stem cells, on microcarriers in a plastic bag bioreactor. The invention enables expansion to therapeutic amounts of stem cells. The method comprises the following steps: a) addition of cells in cell culture medium and microcarriers to a plastic bag container; b) allowing the cells to adhere to the microcarriers while the container is kept substantially still; c) addition of further cell culture medium once the cells have adhered; d) culturing the cells under gentle and constant agitation; e) increase the surface area for continued culturing; and f) final harvesting of cells by an active detachment and separation step.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: December 19, 2017
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Cecilia Anneren, Christian Kaisermayer, Mats Lundgren, Johanna Tschop, Therese Lundstrom, Ann-Christin Magnusson, Gerald Blueml
  • METHOD FOR CELL EXPANSION
    Publication number: 20130236970
    Abstract: The present invention relates to a method for cell expansion. More closely, it relates to a method for expansion of cells, such as mesenchymal stem cells, on microcarriers in a plastic bag bioreactor. The invention enables expansion to therapeutic amounts of stem cells. The method comprises the following steps: a) addition of cells in cell culture medium and microcarriers to a plastic bag container; b) allowing the cells to adhere to the microcarriers while the container is kept substantially still; c) addition of further cell culture medium once the cells have adhered; d) culturing the cells under gentle and constant agitation; e) increase the surface area for continued culturing; and f) final harvesting of cells by an active detachment and separation step.
    Type: Application
    Filed: April 19, 2013
    Publication date: September 12, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: CECILIA ANNEREN, CHRISTIAN KAISERMAYER, MATS LUNDGREN, JOHANNA TSCHOP, THERESE LUNDSTROM, ANN-CHRISTIN MAGNUSSON, GERALD BLUEML