Patents by Inventor Johannes A. M. van der Heyden

Johannes A. M. van der Heyden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bibyclic heteroacrylpiperazine derivatives having psychotropic activity, and pharmaceutical compositions containing these derivatives
    Patent number: 5424313
    Abstract: The invention relates to new compositions with pyschotropic activity which comprise a compound of formula 1 of the formula sheet as the active substance. The compounds of formula 1 are for the greater part new compounds. The invention therefore also relates to these new compounds and to the preparation thereof in a manner known for the synthesis of analogous compounds.
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: June 13, 1995
    Assignee: Duphar International Research B.V.
    Inventors: Jan Hartog, Berend Olivier, Ineke Van Wijngaarden, Cornelis G. Kruse, Johannes A. M. Van Der Heyden, Dirkje A. Van Dalen-Van Der AA
  • Aryl-substituted (N-piperidinyl)methyl- and (N-piperidinyl) methylazoles having antipsychotic properties
    Patent number: 4874770
    Abstract: The invention relates to new aryl-substituted (N-piperidinyl)methyl- and (N-piperazinyl)methylazoles having interesting pharmacological, notably antipsychotic, properties.The compounds may be prepared in a manner known for the synthesis of analogous compounds and be processed to compositions according to known methods.
    Type: Grant
    Filed: July 1, 1988
    Date of Patent: October 17, 1989
    Assignee: Duphar International Research B.V.
    Inventors: Ineke Van Wijngaarden, Cornelis Kruse, Johannes A. M. Van Der Heyden, Martinus T. M. Tulp
  • Phenyl, Pyrrolidin-2-yl substituted pyrroles having antipsychotic properties
    Patent number: 4791132
    Abstract: The invention relates to a group of new phenyl, pyrrolidin-2-yl substituted 5-ring heterocyclic compounds of the formula ##STR1## wherein A is an unsaturated heterocyclic 5-ring having at least one nitrogen or oxygen atom in the ring, with the proviso that the phenyl substituent is in a meta-position with respect to the 2-pyrrolidinyl substituent.The compounds have interesting pharmacological, notably antipsychotic properties.
    Type: Grant
    Filed: September 9, 1987
    Date of Patent: December 13, 1988
    Assignee: Duphar International Research B.V.
    Inventors: Ineke Van Wijngaarden, Cornelis G. Kruse, Roelof Van Hes, Johannes A. M. Van Der Heyden
  • Method of treating psychotropic conditions employing substituted piperazine compounds
    Patent number: 4782061
    Abstract: The invention relates to a group of new bicyclic heteroarylpiperazine derivatives of formula 1. It was found that these compounds have interesting psychotropic in particular anti-psychotic properties.The compounds can be prepared according to methods known for the synthesis of analogous compounds.
    Type: Grant
    Filed: December 18, 1985
    Date of Patent: November 1, 1988
    Assignee: Duphar International Research B.V.
    Inventors: Cornelis G. Kruse, Johannes A. M. van der Heyden, Ineke van Wijngaarden, Jan Hartog, Berend Olivier
  • Phenyl-substituted (N-piperazinyl) methylazoles for treating affections in the central nervous system
    Patent number: 4772604
    Abstract: The invention relates to new aryl-substituted (N-piperidinyl)methyl- and (N-piperazinyl)methylazoles having interesting pharmacological, notably antipsychotic, properties.The compounds may be prepared in a manner known for the synthesis of analogous compounds and be processed to compositions according to known methods.
    Type: Grant
    Filed: February 24, 1987
    Date of Patent: September 20, 1988
    Assignee: Duphar International Research B.V.
    Inventors: Ineke van Wijngaarden, Cornelis G. Kruse, Johannes A. M. van der Heyden, Martinus T. M. Tulp