Patents by Inventor Johannes A. Schumacher

Johannes A. Schumacher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080268464
    Abstract: A process and device are disclosed to determine the activity of enzymes in liquids in a largely automatic manner. The device for carrying out this process has a column (1) with a chromatographic carrier for treating a measurement sample. The carrier is mixed with a substance capable of binding to an enzyme inhibitor present in the measurement sample and that corresponds to at least one enzyme. A measurement sample supply (2) is associated to one end of the column (1). A valve/pump arrangement (7, 11, 14, 15) for filling at least one test tube (5) with a carrier and at least part of the measurement sample is connected downstream of the column (1), in the flow direction of the measurement sample. The carrier is dissociated into cleavage products by the action of the enzyme. The rise in concentration per unit of time of at least one of the cleavage products of the carrier is sensed during an incubation time.
    Type: Application
    Filed: April 25, 2008
    Publication date: October 30, 2008
    Inventors: Johannes Schumacher, Bernd Werle
  • Publication number: 20030087426
    Abstract: A process and device are disclosed to determine the activity of enzymes in liquids in a largely automatic manner. The device for carrying out this process has a column (1) with a chromatographic carrier for treating a measurement sample. The carrier is mixed with a substance capable of binding to an enzyme inhibitor present in the measurement sample and that corresponds to at least one enzyme. A measurement sample supply (2) is associated to one end of the column (1). A valve/pump arrangement (7, 11, 14, 15) for filling at least one test tube (5) with a carrier and at least part of the measurement sample is connected downstream of the column (1), in the flow direction of the measurement sample. The carrier is dissociated into cleavage products by the action of the enzyme. The rise in concentration per unit of time of at least one of the cleavage products of the carrier is sensed during an incubation time.
    Type: Application
    Filed: December 19, 2002
    Publication date: May 8, 2003
    Inventors: Johannes Schumacher, Bernd Werle
  • Publication number: 20010034057
    Abstract: A process and device are disclosed to determine the activity of enzymes in liquids in a largely automatic manner. The device for carrying out this process has a column with an chromatographic carrier for treating a measurement sample. The carrier is mixed with a substance capable of binding to an enzyme inhibitor present in the measurement sample and that corresponds to at least one enzyme. A measurement sample supply is associated to one end of the column. A valve/pump arrangement for filling at least one test tube with a carrier and at least part of the measurement sample is connected downstream of the column, in the flow direction of the measurement sample. The carrier is dissociated into cleavage products by the action of the enzyme. The rise in concentration per unit of time of at least one of the cleavage products of the carrier is sensed during an incubation time.
    Type: Application
    Filed: January 3, 2001
    Publication date: October 25, 2001
    Inventors: Johannes Schumacher, Bernd Werle
  • Patent number: 6171851
    Abstract: A process and device are disclosed to determine the activity of enzymes in liquids in a largely automatic manner. The device for carrying out this process has a column with an chromatographic carrier for treating a measurement sample. The carrier is mixed with a substance capable of binding to an enzyme inhibitor present in the measurement sample and that corresponds to at least one enzyme. A measurement sample supply is associated to one end of the column. A valve/pump arrangement for filling at least one test tube with a carrier and at least part of the measurement sample is connected downstream of the column, in the flow direction of the measurement sample. The carrier is dissociated into cleavage products by the action of the enzyme. The rise in concentration per unit of time of at least one of the cleavage products of the carrier is sensed during an incubation time.
    Type: Grant
    Filed: May 21, 1999
    Date of Patent: January 9, 2001
    Inventors: Johannes Schumacher, Bernd Werle
  • Patent number: 5935846
    Abstract: A process and device are disclosed to determine the activity of enzymes in liquids in a largely automatic manner. The device for carrying out this process has a column with an chromatographic carrier for treating a measurement sample. The carrier is mixed with a substance capable of binding to an enzyme inhibitor present in the measurement sample and that corresponds to at least one enzyme. A measurement sample supply is associated to one end of the column. A valve/pump arrangement for filling at least one test tube with a carrier and at least part of the measurement sample is connected downstream of the column, in the flow direction of the measurement sample. The carrier is dissociated into cleavage products by the action of the enzyme. The rise in concentration per unit of time of at least one of the cleavage products of the carrier is sensed during an incubation time.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: August 10, 1999
    Inventors: Johannes Schumacher, Bernd Werle
  • Patent number: 5559288
    Abstract: A volume sensor for liquids comprising a measuring chamber in which toothed meter wheels mesh with one another and are mounted on stationary pivots. Flow paths are formed in at least one of the measuring-chamber end walls and are separated by a web in the pivot plane, the edges of which are substantially symmetrical with the pivot plane. The tooth spaces of the meter wheels, at least on the side facing the flow paths, are formed with a recess which extends radially inwards compared with the root circle and is symmetrical in respect to the tooth space. The web is constructed so that whenever a tooth space of the two meter wheels is in the centre position in the pivot plane, the edges of the web substantially coincide in shape with the neighbouring flanks of the teeth adjacent the tooth space so that the latter is cut off from the flow paths in the end walls. The flow paths allow the liquid pressure to be reduced before the tooth space is closed off.
    Type: Grant
    Filed: December 7, 1995
    Date of Patent: September 24, 1996
    Assignee: VSE Schweisstechnik GmbH
    Inventor: Johannes A. Schumacher
  • Patent number: 4425789
    Abstract: A monitoring system for hydraulic pipelines and/or actuating devices including a volume flow sensor having a toothed rotor similar to that in a toothed rotor motor by which movements of the toothed rotor can be sensed by no-contact detectors which emit electrical pulses in respect of discrete quantities of oil displaced by and equal to the volume of a tooth of the toothed rotor. The system also includes a device by which the pulses are processed with respect to the direction of flow through the volume flow sensor and to the pulse frequency. The system also includes an indicator indicative of current operating conditions and a counter by which, after a limiting frequency has been exceeded, the pulses are counted and upon reaching a specified pre-assigned number of pulses that succeed one another during a period of uninterrupted counting a signal of leakiness is generated.
    Type: Grant
    Filed: October 9, 1981
    Date of Patent: January 17, 1984
    Assignee: Kracht Pumpen- und Motorenfabrik GmbH & Co. KG
    Inventors: Borislav Andreev, Johannes A. Schumacher